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Items: 1 to 20 of 107


CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer.

Wang S, Wu X, Zhang J, Chen Y, Xu J, Xia X, He S, Qiang F, Li A, Shu Y, Røe OD, Li G, Zhou JW.

Gut. 2013 Apr;62(4):496-508. doi: 10.1136/gutjnl-2011-301522.


Prognostic significance of BRMS1 expression in human melanoma and its role in tumor angiogenesis.

Li J, Cheng Y, Tai D, Martinka M, Welch DR, Li G.

Oncogene. 2011 Feb 24;30(8):896-906. doi: 10.1038/onc.2010.470.


CHIP/Stub1 functions as a tumor suppressor and represses NF-κB-mediated signaling in colorectal cancer.

Wang Y, Ren F, Wang Y, Feng Y, Wang D, Jia B, Qiu Y, Wang S, Yu J, Sung JJ, Xu J, Zeps N, Chang Z.

Carcinogenesis. 2014 May;35(5):983-91. doi: 10.1093/carcin/bgt393.


Ubiquitin ligase CHIP induces TRAF2 proteasomal degradation and NF-κB inactivation to regulate breast cancer cell invasion.

Jang KW, Lee KH, Kim SH, Jin T, Choi EY, Jeon HJ, Kim E, Han YS, Chung JH.

J Cell Biochem. 2011 Dec;112(12):3612-20. doi: 10.1002/jcb.23292.


The ubiquitin ligase CHIP inactivates NF-κB signaling and impairs the ability of migration and invasion in gastric cancer cells.

Liu F, Zhou J, Zhou P, Chen W, Guo F.

Int J Oncol. 2015 May;46(5):2096-106. doi: 10.3892/ijo.2015.2893.


CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis.

Yang G, Rosen DG, Liu G, Yang F, Guo X, Xiao X, Xue F, Mercado-Uribe I, Huang J, Lin SH, Mills GB, Liu J.

Clin Cancer Res. 2010 Aug 1;16(15):3875-86. doi: 10.1158/1078-0432.CCR-10-0483.


Combined prognostic value of both RelA and IkappaB-alpha expression in human non-small cell lung cancer.

Zhang D, Jin X, Wang F, Wang S, Deng C, Gao Z, Guo C.

Ann Surg Oncol. 2007 Dec;14(12):3581-92.


A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis.

Nam SY, Ko YS, Jung J, Yoon J, Kim YH, Choi YJ, Park JW, Chang MS, Kim WH, Lee BL.

Br J Cancer. 2011 Jan 4;104(1):166-74. doi: 10.1038/sj.bjc.6606020.


Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival.

Xu L, Li X, Chu ES, Zhao G, Go MY, Tao Q, Jin H, Zeng Z, Sung JJ, Yu J.

Gut. 2012 Jul;61(7):977-85. doi: 10.1136/gutjnl-2011-300411.


JWA suppresses tumor angiogenesis via Sp1-activated matrix metalloproteinase-2 and its prognostic significance in human gastric cancer.

Chen Y, Huang Y, Huang Y, Xia X, Zhang J, Zhou Y, Tan Y, He S, Qiang F, Li A, Re OD, Li G, Zhou J.

Carcinogenesis. 2014 Feb;35(2):442-51. doi: 10.1093/carcin/bgt311.


Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer.

Lee BL, Lee HS, Jung J, Cho SJ, Chung HY, Kim WH, Jin YW, Kim CS, Nam SY.

Clin Cancer Res. 2005 Apr 1;11(7):2518-25.


Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients.

Li X, Cheung KF, Ma X, Tian L, Zhao J, Go MY, Shen B, Cheng AS, Ying J, Tao Q, Sung JJ, Kung HF, Yu J.

Oncogene. 2012 Jul 19;31(29):3419-30. doi: 10.1038/onc.2011.511. Erratum in: Oncogene. 2012 Jul 19;31(29):3482.


Nuclear factor-kappaB mediates angiogenesis and metastasis of human bladder cancer through the regulation of interleukin-8.

Karashima T, Sweeney P, Kamat A, Huang S, Kim SJ, Bar-Eli M, McConkey DJ, Dinney CP.

Clin Cancer Res. 2003 Jul;9(7):2786-97.


Metastatic lymph node CHIP expression is a potential prognostic marker for resected esophageal squamous cell carcinoma patients.

Wen J, Luo KJ, Hu Y, Yang H, Fu JH.

Ann Surg Oncol. 2013 May;20(5):1668-75. doi: 10.1245/s10434-012-2733-4.


Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.

Song X, Yao J, Wang F, Zhou M, Zhou Y, Wang H, Wei L, Zhao L, Li Z, Lu N, Guo Q.

Toxicol Appl Pharmacol. 2013 Sep 1;271(2):144-55. doi: 10.1016/j.taap.2013.04.031.


Carboxyl terminus of Hsp70-interacting protein regulation of osteoclast formation in mice through promotion of tumor necrosis factor receptor-associated factor 6 protein degradation.

Li S, Shu B, Zhang Y, Li J, Guo J, Wang Y, Ren F, Xiao G, Chang Z, Chen D.

Arthritis Rheumatol. 2014 Jul;66(7):1854-63. doi: 10.1002/art.38521.


CHIP is a novel tumor suppressor in pancreatic cancer through targeting EGFR.

Wang T, Yang J, Xu J, Li J, Cao Z, Zhou L, You L, Shu H, Lu Z, Li H, Li M, Zhang T, Zhao Y.

Oncotarget. 2014 Apr 15;5(7):1969-86.


TRIM59 is up-regulated in gastric tumors, promoting ubiquitination and degradation of p53.

Zhou Z, Ji Z, Wang Y, Li J, Cao H, Zhu HH, Gao WQ.

Gastroenterology. 2014 Nov;147(5):1043-54. doi: 10.1053/j.gastro.2014.07.021.

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