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Items: 1 to 20 of 150

3.

Structural and functional studies of FKHR-PAX3, a reciprocal fusion gene of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma.

Hu Q, Yuan Y, Wang C.

PLoS One. 2013 Jun 14;8(6):e68065. doi: 10.1371/journal.pone.0068065. Print 2013.

4.

PAX3-FKHR regulates the expression of pleiotrophin to mediate motility in alveolar rhabdomyosarcoma cells.

Liu L, Chen T.

J Can Res Updates. 2012 Jan 1;1(1). doi: 10.6000/1929-2279.2012.01.01.09.

5.
6.

Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target.

Mercado GE, Xia SJ, Zhang C, Ahn EH, Gustafson DM, Laé M, Ladanyi M, Barr FG.

Genes Chromosomes Cancer. 2008 Jun;47(6):510-20. doi: 10.1002/gcc.20554.

PMID:
18335505
7.

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3.

Fredericks WJ, Galili N, Mukhopadhyay S, Rovera G, Bennicelli J, Barr FG, Rauscher FJ 3rd.

Mol Cell Biol. 1995 Mar;15(3):1522-35.

8.

Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer.

Cao L, Yu Y, Bilke S, Walker RL, Mayeenuddin LH, Azorsa DO, Yang F, Pineda M, Helman LJ, Meltzer PS.

Cancer Res. 2010 Aug 15;70(16):6497-508. doi: 10.1158/0008-5472.CAN-10-0582. Epub 2010 Jul 27.

9.
10.

PAX3/forkhead homolog in rhabdomyosarcoma oncoprotein activates glucose transporter 4 gene expression in vivo and in vitro.

Armoni M, Quon MJ, Maor G, Avigad S, Shapiro DN, Harel C, Esposito D, Goshen Y, Yaniv I, Karnieli E.

J Clin Endocrinol Metab. 2002 Nov;87(11):5312-24.

PMID:
12414908
11.

Inducible short-term and stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression.

Tomescu O, Xia SJ, Strezlecki D, Bennicelli JL, Ginsberg J, Pawel B, Barr FG.

Lab Invest. 2004 Aug;84(8):1060-70.

12.

Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas.

Davicioni E, Finckenstein FG, Shahbazian V, Buckley JD, Triche TJ, Anderson MJ.

Cancer Res. 2006 Jul 15;66(14):6936-46.

13.

Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma.

Taulli R, Scuoppo C, Bersani F, Accornero P, Forni PE, Miretti S, Grinza A, Allegra P, Schmitt-Ney M, Crepaldi T, Ponzetto C.

Cancer Res. 2006 May 1;66(9):4742-9.

14.

Global gene expression profiling of PAX-FKHR fusion-positive alveolar and PAX-FKHR fusion-negative embryonal rhabdomyosarcomas.

Laé M, Ahn EH, Mercado GE, Chuai S, Edgar M, Pawel BR, Olshen A, Barr FG, Ladanyi M.

J Pathol. 2007 Jun;212(2):143-51.

PMID:
17471488
15.

Hormone-dependent tumor regression in vivo by an inducible transcriptional repressor directed at the PAX3-FKHR oncogene.

Ayyanathan K, Fredericks WJ, Berking C, Herlyn M, Balakrishnan C, Gunther E, Rauscher FJ 3rd.

Cancer Res. 2000 Oct 15;60(20):5803-14.

16.

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis.

Graf Finckenstein F, Shahbazian V, Davicioni E, Ren YX, Anderson MJ.

Oncogene. 2008 Mar 27;27(14):2004-14. Epub 2007 Oct 8.

PMID:
17922034
17.

Effects of PAX3-FKHR on malignant phenotypes in alveolar rhabdomyosarcoma.

Kikuchi K, Tsuchiya K, Otabe O, Gotoh T, Tamura S, Katsumi Y, Yagyu S, Tsubai-Shimizu S, Miyachi M, Iehara T, Hosoi H.

Biochem Biophys Res Commun. 2008 Jan 18;365(3):568-74. Epub 2007 Nov 20.

PMID:
18022385
18.

Genetic heterogeneity in the alveolar rhabdomyosarcoma subset without typical gene fusions.

Barr FG, Qualman SJ, Macris MH, Melnyk N, Lawlor ER, Strzelecki DM, Triche TJ, Bridge JA, Sorensen PH.

Cancer Res. 2002 Aug 15;62(16):4704-10.

19.
20.

p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment.

Hecker RM, Amstutz RA, Wachtel M, Walter D, Niggli FK, Schäfer BW.

Oncogene. 2010 Jul 8;29(27):3942-52. doi: 10.1038/onc.2010.145. Epub 2010 May 10.

PMID:
20453878

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