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Items: 1 to 20 of 215


Mind bomb 1 is required for pancreatic β-cell formation.

Horn S, Kobberup S, Jørgensen MC, Kalisz M, Klein T, Kageyama R, Gegg M, Lickert H, Lindner J, Magnuson MA, Kong YY, Serup P, Ahnfelt-Rønne J, Jensen JN.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7356-61. doi: 10.1073/pnas.1203605109. Epub 2012 Apr 23.


Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.

Fukuda A, Kawaguchi Y, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Koizumi M, Boyer DF, Fujimoto K, Doi R, Kageyama R, Wright CV, Chiba T.

J Clin Invest. 2006 Jun;116(6):1484-93. Epub 2006 May 18.


Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.

Schaffer AE, Freude KK, Nelson SB, Sander M.

Dev Cell. 2010 Jun 15;18(6):1022-9. doi: 10.1016/j.devcel.2010.05.015.


Ectopic Ptf1a expression in murine ESCs potentiates endocrine differentiation and models pancreas development in vitro.

Nair GG, Vincent RK, Odorico JS.

Stem Cells. 2014 May;32(5):1195-207. doi: 10.1002/stem.1616.


The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors.

Kim SY, Rane SG.

Development. 2011 May;138(10):1903-12. doi: 10.1242/dev.061481. Epub 2011 Apr 13.


Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment.

Qu X, Afelik S, Jensen JN, Bukys MA, Kobberup S, Schmerr M, Xiao F, Nyeng P, Veronica Albertoni M, Grapin-Botton A, Jensen J.

Dev Biol. 2013 Apr 1;376(1):1-12. doi: 10.1016/j.ydbio.2013.01.021. Epub 2013 Jan 29.


Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.

Soyer J, Flasse L, Raffelsberger W, Beucher A, Orvain C, Peers B, Ravassard P, Vermot J, Voz ML, Mellitzer G, Gradwohl G.

Development. 2010 Jan;137(2):203-12. doi: 10.1242/dev.041673.


Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism.

Ahnfelt-Rønne J, Jørgensen MC, Klinck R, Jensen JN, Füchtbauer EM, Deering T, MacDonald RJ, Wright CV, Madsen OD, Serup P.

Development. 2012 Jan;139(1):33-45. doi: 10.1242/dev.071761. Epub 2011 Nov 17.


Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration.

Ghaye AP, Bergemann D, Tarifeño-Saldivia E, Flasse LC, Von Berg V, Peers B, Voz ML, Manfroid I.

BMC Biol. 2015 Sep 2;13:70. doi: 10.1186/s12915-015-0179-4.


Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning.

Baumgartner BK, Cash G, Hansen H, Ostler S, Murtaugh LC.

Dev Biol. 2014 Jul 1;391(1):89-98. doi: 10.1016/j.ydbio.2014.03.019. Epub 2014 Apr 8.


Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish.

Kimmel RA, Onder L, Wilfinger A, Ellertsdottir E, Meyer D.

BMC Biol. 2011 Oct 31;9:75. doi: 10.1186/1741-7007-9-75.


Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.

Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG.

Genes Dev. 2006 Oct 1;20(19):2739-53.


Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells.

Burlison JS, Long Q, Fujitani Y, Wright CV, Magnuson MA.

Dev Biol. 2008 Apr 1;316(1):74-86. doi: 10.1016/j.ydbio.2008.01.011. Epub 2008 Jan 26.


Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish.

Flasse LC, Pirson JL, Stern DG, Von Berg V, Manfroid I, Peers B, Voz ML.

BMC Biol. 2013 Jul 8;11:78. doi: 10.1186/1741-7007-11-78.


Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas.

Kopinke D, Brailsford M, Shea JE, Leavitt R, Scaife CL, Murtaugh LC.

Development. 2011 Feb;138(3):431-41. doi: 10.1242/dev.053843.


NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas.

Henseleit KD, Nelson SB, Kuhlbrodt K, Hennings JC, Ericson J, Sander M.

Development. 2005 Jul;132(13):3139-49.


Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas.

Mastracci TL, Anderson KR, Papizan JB, Sussel L.

PLoS Genet. 2013;9(2):e1003278. doi: 10.1371/journal.pgen.1003278. Epub 2013 Feb 7.


Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration.

Pan FC, Bankaitis ED, Boyer D, Xu X, Van de Casteele M, Magnuson MA, Heimberg H, Wright CV.

Development. 2013 Feb;140(4):751-64. doi: 10.1242/dev.090159. Epub 2013 Jan 16.


TNF-like weak inducer of apoptosis (TWEAK) promotes beta cell neogenesis from pancreatic ductal epithelium in adult mice.

Wu F, Guo L, Jakubowski A, Su L, Li WC, Bonner-Weir S, Burkly LC.

PLoS One. 2013 Aug 26;8(8):e72132. doi: 10.1371/journal.pone.0072132. eCollection 2013.

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