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Items: 1 to 20 of 119

1.

Antibodies to pathogenic epitopes on type XVII collagen cause skin fragility in a complement-dependent and -independent manner.

Natsuga K, Nishie W, Shinkuma S, Ujiie H, Nishimura M, Sawamura D, Shimizu H.

J Immunol. 2012 Jun 1;188(11):5792-9. doi: 10.4049/jimmunol.1003402. Epub 2012 Apr 20.

2.

Noncollagenous 16A domain of type XVII collagen-reactive CD4+ T cells play a pivotal role in the development of active disease in experimental bullous pemphigoid model.

Ujiie H, Shibaki A, Nishie W, Shinkuma S, Moriuchi R, Qiao H, Shimizu H.

Clin Immunol. 2012 Feb;142(2):167-75. doi: 10.1016/j.clim.2011.10.002. Epub 2011 Oct 17.

PMID:
22044750
3.

Bullous pemphigoid autoantibodies directly induce blister formation without complement activation.

Ujiie H, Sasaoka T, Izumi K, Nishie W, Shinkuma S, Natsuga K, Nakamura H, Shibaki A, Shimizu H.

J Immunol. 2014 Nov 1;193(9):4415-28. doi: 10.4049/jimmunol.1400095. Epub 2014 Sep 26.

4.

A novel active mouse model for bullous pemphigoid targeting humanized pathogenic antigen.

Ujiie H, Shibaki A, Nishie W, Sawamura D, Wang G, Tateishi Y, Li Q, Moriuchi R, Qiao H, Nakamura H, Akiyama M, Shimizu H.

J Immunol. 2010 Feb 15;184(4):2166-74. doi: 10.4049/jimmunol.0903101. Epub 2010 Jan 20.

5.

Anti-collagen XVII single-chain Fv antibody blocks the autoimmune reaction mediated by pathogenic autoantibodies in bullous pemphigoid.

Wu Y, Sun NN, Dang EL, Jin L, Liu ZF, Zhang W, Yang LT, Wang G.

J Dermatol Sci. 2013 Oct;72(1):25-31. doi: 10.1016/j.jdermsci.2013.05.010. Epub 2013 Jun 13.

PMID:
23827201
6.

What's new in bullous pemphigoid.

Ujiie H, Shibaki A, Nishie W, Shimizu H.

J Dermatol. 2010 Mar;37(3):194-204. doi: 10.1111/j.1346-8138.2009.00792.x. Review.

PMID:
20507382
7.

Epitope-Dependent Pathogenicity of Antibodies Targeting a Major Bullous Pemphigoid Autoantigen Collagen XVII/BP180.

Wada M, Nishie W, Ujiie H, Izumi K, Iwata H, Natsuga K, Nakamura H, Kitagawa Y, Shimizu H.

J Invest Dermatol. 2016 May;136(5):938-46. doi: 10.1016/j.jid.2015.11.030. Epub 2016 Jan 28.

8.

Context-Dependent Regulation of Collagen XVII Ectodomain Shedding in Skin.

Nishie W, Natsuga K, Iwata H, Izumi K, Ujiie H, Toyonaga E, Hata H, Nakamura H, Shimizu H.

Am J Pathol. 2015 May;185(5):1361-71. doi: 10.1016/j.ajpath.2015.01.012. Epub 2015 Mar 13.

PMID:
25773176
9.

Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model.

Li Q, Ujiie H, Shibaki A, Wang G, Moriuchi R, Qiao HJ, Morioka H, Shinkuma S, Natsuga K, Long HA, Nishie W, Shimizu H.

J Immunol. 2010 Dec 15;185(12):7746-55. doi: 10.4049/jimmunol.1000667. Epub 2010 Nov 12.

10.

[Novel animal models for bullous pemphigoid utilized by "humanization of autoantigen"].

Nishie W, Shimizu H.

Nihon Rinsho Meneki Gakkai Kaishi. 2009 Dec;32(6):472-7. Review. Japanese.

11.

Mouse models of autoimmune blistering diseases induced by the passive transfer of antibodies.

Nishie W.

Methods Mol Biol. 2013;961:363-9. doi: 10.1007/978-1-62703-227-8_24.

PMID:
23325657
12.

A novel humanized neonatal autoimmune blistering skin disease model induced by maternally transferred antibodies.

Nishie W, Sawamura D, Natsuga K, Shinkuma S, Goto M, Shibaki A, Ujiie H, Olasz E, Yancey KB, Shimizu H.

J Immunol. 2009 Sep 15;183(6):4088-93. doi: 10.4049/jimmunol.0800389. Epub 2009 Aug 28.

13.

Humanization of autoantigen.

Nishie W, Sawamura D, Goto M, Ito K, Shibaki A, McMillan JR, Sakai K, Nakamura H, Olasz E, Yancey KB, Akiyama M, Shimizu H.

Nat Med. 2007 Mar;13(3):378-83. Epub 2007 Feb 25.

PMID:
17322897
14.

Update on the pathogenesis of bullous pemphigoid: an autoantibody-mediated blistering disease targeting collagen XVII.

Nishie W.

J Dermatol Sci. 2014 Mar;73(3):179-86. doi: 10.1016/j.jdermsci.2013.12.001. Epub 2013 Dec 27. Review.

PMID:
24434029
15.

IgE autoantibodies against the intracellular domain of BP180.

Dresow SK, Sitaru C, Recke A, Oostingh GJ, Zillikens D, Gibbs BF.

Br J Dermatol. 2009 Feb;160(2):429-32. doi: 10.1111/j.1365-2133.2008.08858.x. Epub 2008 Sep 19.

PMID:
18808416
16.

Subepidermal blistering induced by human autoantibodies to BP180 requires innate immune players in a humanized bullous pemphigoid mouse model.

Liu Z, Sui W, Zhao M, Li Z, Li N, Thresher R, Giudice GJ, Fairley JA, Sitaru C, Zillikens D, Ning G, Marinkovich MP, Diaz LA.

J Autoimmun. 2008 Dec;31(4):331-8. doi: 10.1016/j.jaut.2008.08.009. Epub 2008 Oct 14.

17.

The flavonoid luteolin inhibits Fcγ-dependent respiratory burst in granulocytes, but not skin blistering in a new model of pemphigoid in adult mice.

Oswald E, Sesarman A, Franzke CW, Wölfle U, Bruckner-Tuderman L, Jakob T, Martin SF, Sitaru C.

PLoS One. 2012;7(2):e31066. doi: 10.1371/journal.pone.0031066. Epub 2012 Feb 6.

18.

Cloning of hamster type XVII collagen cDNA, and pathogenesis of anti-type XVII collagen antibody and complement in hamster bullous pemphigoid.

Yamamoto K, Inoue N, Masuda R, Fujimori A, Saito T, Imajoh-Ohmi S, Shinkai H, Sakiyama H.

J Invest Dermatol. 2002 Mar;118(3):485-92.

19.

Autoantibody Profile Differentiates between Inflammatory and Noninflammatory Bullous Pemphigoid.

Izumi K, Nishie W, Mai Y, Wada M, Natsuga K, Ujiie H, Iwata H, Yamagami J, Shimizu H.

J Invest Dermatol. 2016 Nov;136(11):2201-2210. doi: 10.1016/j.jid.2016.06.622. Epub 2016 Jul 14.

PMID:
27424319

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