Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 288


Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.

Hui B, Shi YH, Ding ZB, Zhou J, Gu CY, Peng YF, Yang H, Liu WR, Shi GM, Fan J.

Cancer. 2012 Nov 15;118(22):5560-71. doi: 10.1002/cncr.27586. Epub 2012 Apr 19.


An autophagy inhibitor enhances the inhibition of cell proliferation induced by a proteasome inhibitor in MCF-7 cells.

Yao F, Wang G, Wei W, Tu Y, Tong H, Sun S.

Mol Med Rep. 2012 Jan;5(1):84-8. doi: 10.3892/mmr.2011.590. Epub 2011 Sep 19.


Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells.

Ge PF, Zhang JZ, Wang XF, Meng FK, Li WC, Luan YX, Ling F, Luo YN.

Acta Pharmacol Sin. 2009 Jul;30(7):1046-52. doi: 10.1038/aps.2009.71.


Inhibition of autophagy enhances apoptosis induced by proteasome inhibitor bortezomib in human glioblastoma U87 and U251 cells.

Zhang X, Li W, Wang C, Leng X, Lian S, Feng J, Li J, Wang H.

Mol Cell Biochem. 2014 Jan;385(1-2):265-75. doi: 10.1007/s11010-013-1835-z. Epub 2013 Oct 9.


Effect of inhibition of the ubiquitin-proteasome system and Hsp90 on growth and survival of rhabdomyosarcoma cells in vitro.

Peron M, Bonvini P, Rosolen A.

BMC Cancer. 2012 Jun 12;12:233. doi: 10.1186/1471-2407-12-233.


Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model.

Wang C, Gao D, Guo K, Kang X, Jiang K, Sun C, Li Y, Sun L, Shu H, Jin G, Sun H, Wu W, Liu Y.

BMC Cancer. 2012 May 4;12:166. doi: 10.1186/1471-2407-12-166.


Cancerous inhibitor of protein phosphatase 2A mediates bortezomib-induced autophagy in hepatocellular carcinoma independent of proteasome.

Yu HC, Hou DR, Liu CY, Lin CS, Shiau CW, Cheng AL, Chen KF.

PLoS One. 2013;8(2):e55705. doi: 10.1371/journal.pone.0055705. Epub 2013 Feb 1.


Beclin 1 enhances proteasome inhibition-mediated cytotoxicity of thyroid cancer cells in macroautophagy-independent manner.

Zhang HY, Du ZX, Meng X, Zong ZH, Wang HQ.

J Clin Endocrinol Metab. 2013 Feb;98(2):E217-26. doi: 10.1210/jc.2012-2679. Epub 2012 Dec 21.


Effect of autophagy on multiple myeloma cell viability.

Hoang B, Benavides A, Shi Y, Frost P, Lichtenstein A.

Mol Cancer Ther. 2009 Jul;8(7):1974-84. doi: 10.1158/1535-7163.MCT-08-1177. Epub 2009 Jun 9.


Autophagy-independent enhancing effects of Beclin 1 on cytotoxicity of ovarian cancer cells mediated by proteasome inhibitors.

Liu C, Yan X, Wang HQ, Gao YY, Liu J, Hu Z, Liu D, Gao J, Lin B.

BMC Cancer. 2012 Dec 27;12:622. doi: 10.1186/1471-2407-12-622.


Antitumor effects of proteasome inhibition in anaplastic thyroid carcinoma.

Altmann A, Markert A, Askoxylakis V, Schöning T, Jesenofsky R, Eisenhut M, Haberkorn U.

J Nucl Med. 2012 Nov;53(11):1764-71. doi: 10.2967/jnumed.111.101295. Epub 2012 Oct 10.


1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.

Vanderlaag K, Su Y, Frankel AE, Burghardt RC, Barhoumi R, Chadalapaka G, Jutooru I, Safe S.

BMC Cancer. 2010 Dec 3;10:669. doi: 10.1186/1471-2407-10-669.


Bortezomib induces protective autophagy through AMP-activated protein kinase activation in cultured pancreatic and colorectal cancer cells.

Min H, Xu M, Chen ZR, Zhou JD, Huang M, Zheng K, Zou XP.

Cancer Chemother Pharmacol. 2014 Jul;74(1):167-76. doi: 10.1007/s00280-014-2451-7. Epub 2014 May 20.


Restoration of klotho expression induces apoptosis and autophagy in hepatocellular carcinoma cells.

Shu G, Xie B, Ren F, Liu DC, Zhou J, Li Q, Chen J, Yuan L, Zhou J.

Cell Oncol (Dordr). 2013 Apr;36(2):121-9. doi: 10.1007/s13402-012-0118-0. Epub 2012 Dec 18.


Down-regulation of phospho-Akt is a major molecular determinant of bortezomib-induced apoptosis in hepatocellular carcinoma cells.

Chen KF, Yeh PY, Yeh KH, Lu YS, Huang SY, Cheng AL.

Cancer Res. 2008 Aug 15;68(16):6698-707. doi: 10.1158/0008-5472.CAN-08-0257.


BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways.

Rapino F, Jung M, Fulda S.

Oncogene. 2014 Mar 27;33(13):1713-24. doi: 10.1038/onc.2013.110. Epub 2013 May 6.


Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation.

Kao C, Chao A, Tsai CL, Chuang WC, Huang WP, Chen GC, Lin CY, Wang TH, Wang HS, Lai CH.

Cell Death Dis. 2014 Nov 6;5:e1510. doi: 10.1038/cddis.2014.468.


Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.

Shimizu S, Takehara T, Hikita H, Kodama T, Tsunematsu H, Miyagi T, Hosui A, Ishida H, Tatsumi T, Kanto T, Hiramatsu N, Fujita N, Yoshimori T, Hayashi N.

Int J Cancer. 2012 Aug 1;131(3):548-57. doi: 10.1002/ijc.26374. Epub 2011 Sep 12.


Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.

Nencioni A, Wille L, Dal Bello G, Boy D, Cirmena G, Wesselborg S, Belka C, Brossart P, Patrone F, Ballestrero A.

Clin Cancer Res. 2005 Jun 1;11(11):4259-65.


Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells.

Wu WK, Wu YC, Yu L, Li ZJ, Sung JJ, Cho CH.

Biochem Biophys Res Commun. 2008 Sep 19;374(2):258-63. doi: 10.1016/j.bbrc.2008.07.031. Epub 2008 Jul 16.


Supplemental Content

Support Center