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Items: 1 to 20 of 108

1.

Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4.

Dapito DH, Mencin A, Gwak GY, Pradere JP, Jang MK, Mederacke I, Caviglia JM, Khiabanian H, Adeyemi A, Bataller R, Lefkowitch JH, Bower M, Friedman R, Sartor RB, Rabadan R, Schwabe RF.

Cancer Cell. 2012 Apr 17;21(4):504-16. doi: 10.1016/j.ccr.2012.02.007.

2.

Targeting gut flora to prevent progression of hepatocellular carcinoma.

Darnaud M, Faivre J, Moniaux N.

J Hepatol. 2013 Feb;58(2):385-7. doi: 10.1016/j.jhep.2012.08.019. Epub 2012 Aug 30.

3.

TLR4 Deficiency Protects against Hepatic Fibrosis and Diethylnitrosamine-Induced Pre-Carcinogenic Liver Injury in Fibrotic Liver.

Weber SN, Bohner A, Dapito DH, Schwabe RF, Lammert F.

PLoS One. 2016 Jul 8;11(7):e0158819. doi: 10.1371/journal.pone.0158819. eCollection 2016.

4.

Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents.

Yu LX, Yan HX, Liu Q, Yang W, Wu HP, Dong W, Tang L, Lin Y, He YQ, Zou SS, Wang C, Zhang HL, Cao GW, Wu MC, Wang HY.

Hepatology. 2010 Oct;52(4):1322-33. doi: 10.1002/hep.23845.

PMID:
20803560
5.

Gut-derived lipopolysaccharide promotes T-cell-mediated hepatitis in mice through Toll-like receptor 4.

Lin Y, Yu LX, Yan HX, Yang W, Tang L, Zhang HL, Liu Q, Zou SS, He YQ, Wang C, Wu MC, Wang HY.

Cancer Prev Res (Phila). 2012 Sep;5(9):1090-102. doi: 10.1158/1940-6207.CAPR-11-0364. Epub 2012 May 22.

6.

The Toll-like receptors TLR2 and TLR4 do not affect the intestinal microbiota composition in mice.

Loh G, Brodziak F, Blaut M.

Environ Microbiol. 2008 Mar;10(3):709-15. Epub 2007 Nov 25.

PMID:
18036181
7.

Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens.

Fox JG, Feng Y, Theve EJ, Raczynski AR, Fiala JL, Doernte AL, Williams M, McFaline JL, Essigmann JM, Schauer DB, Tannenbaum SR, Dedon PC, Weinman SA, Lemon SM, Fry RC, Rogers AB.

Gut. 2010 Jan;59(1):88-97. doi: 10.1136/gut.2009.183749.

8.

Toll-like receptor 4 differentially regulates epidermal growth factor-related growth factors in response to intestinal mucosal injury.

Hsu D, Fukata M, Hernandez YG, Sotolongo JP, Goo T, Maki J, Hayes LA, Ungaro RC, Chen A, Breglio KJ, Xu R, Abreu MT.

Lab Invest. 2010 Sep;90(9):1295-305. doi: 10.1038/labinvest.2010.100. Epub 2010 May 24.

9.

Profound impact of gut homeostasis on chemically-induced pro-tumorigenic inflammation and hepatocarcinogenesis in rats.

Zhang HL, Yu LX, Yang W, Tang L, Lin Y, Wu H, Zhai B, Tan YX, Shan L, Liu Q, Chen HY, Dai RY, Qiu BJ, He YQ, Wang C, Zheng LY, Li YQ, Wu FQ, Li Z, Yan HX, Wang HY.

J Hepatol. 2012 Oct;57(4):803-12. doi: 10.1016/j.jhep.2012.06.011. Epub 2012 Jun 19.

PMID:
22727732
10.

Intestinal Epithelial Toll-Like Receptor 4 Signaling Affects Epithelial Function and Colonic Microbiota and Promotes a Risk for Transmissible Colitis.

Dheer R, Santaolalla R, Davies JM, Lang JK, Phillips MC, Pastorini C, Vazquez-Pertejo MT, Abreu MT.

Infect Immun. 2016 Jan 11;84(3):798-810. doi: 10.1128/IAI.01374-15.

11.

DNA attenuates enterocyte Toll-like receptor 4-mediated intestinal mucosal injury after remote trauma.

Sodhi C, Levy R, Gill R, Neal MD, Richardson W, Branca M, Russo A, Prindle T, Billiar TR, Hackam DJ.

Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G862-73. doi: 10.1152/ajpgi.00373.2010. Epub 2011 Jan 13.

12.

Gut microbiota and probiotics in chronic liver diseases.

Cesaro C, Tiso A, Del Prete A, Cariello R, Tuccillo C, Cotticelli G, Del Vecchio Blanco C, Loguercio C.

Dig Liver Dis. 2011 Jun;43(6):431-8. doi: 10.1016/j.dld.2010.10.015. Epub 2010 Dec 16. Review.

PMID:
21163715
13.

Gut microbiota and liver diseases.

Minemura M, Shimizu Y.

World J Gastroenterol. 2015 Feb 14;21(6):1691-702. doi: 10.3748/wjg.v21.i6.1691. Review.

14.

Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis.

Neal MD, Sodhi CP, Jia H, Dyer M, Egan CE, Yazji I, Good M, Afrazi A, Marino R, Slagle D, Ma C, Branca MF, Prindle T Jr, Grant Z, Ozolek J, Hackam DJ.

J Biol Chem. 2012 Oct 26;287(44):37296-308. doi: 10.1074/jbc.M112.375881. Epub 2012 Sep 6.

15.

Role of Gut Microbiota in Liver Disease.

Brenner DA, Paik YH, Schnabl B.

J Clin Gastroenterol. 2015 Nov-Dec;49 Suppl 1:S25-7. doi: 10.1097/MCG.0000000000000391.

16.

Lactobacillus rhamnosus GG reduces hepatic TNFα production and inflammation in chronic alcohol-induced liver injury.

Wang Y, Liu Y, Kirpich I, Ma Z, Wang C, Zhang M, Suttles J, McClain C, Feng W.

J Nutr Biochem. 2013 Sep;24(9):1609-15. doi: 10.1016/j.jnutbio.2013.02.001. Epub 2013 Apr 22.

17.

Commensal microflora induce host defense and decrease bacterial translocation in burn mice through toll-like receptor 4.

Chen LW, Chang WJ, Chen PH, Hsu CM.

J Biomed Sci. 2010 Jun 12;17:48. doi: 10.1186/1423-0127-17-48.

18.

Apoptosis in stages of mouse hepatocarcinogenesis: failure to counterbalance cell proliferation and to account for strain differences in tumor susceptibility.

Bursch W, Chabicovsky M, Wastl U, Grasl-Kraupp B, Bukowska K, Taper H, Schulte-Hermann R.

Toxicol Sci. 2005 May;85(1):515-29. Epub 2005 Feb 23.

PMID:
15728704
19.

Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1.

Yang L, Inokuchi S, Roh YS, Song J, Loomba R, Park EJ, Seki E.

Gastroenterology. 2013 May;144(5):1042-1054.e4. doi: 10.1053/j.gastro.2013.01.056. Epub 2013 Feb 4.

20.

Toll-like receptor 2-mediated intestinal injury and enteric tumor necrosis factor receptor I contribute to liver fibrosis in mice.

Hartmann P, Haimerl M, Mazagova M, Brenner DA, Schnabl B.

Gastroenterology. 2012 Nov;143(5):1330-40.e1. doi: 10.1053/j.gastro.2012.07.099. Epub 2012 Jul 27.

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