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Items: 1 to 20 of 94

1.

Mutation of conserved histidines alters tertiary structure and nanomechanics of consensus ankyrin repeats.

Lee W, Strümpfer J, Bennett V, Schulten K, Marszalek PE.

J Biol Chem. 2012 Jun 1;287(23):19115-21. doi: 10.1074/jbc.M112.365569. Epub 2012 Apr 18.

2.

Mechanical anisotropy of ankyrin repeats.

Lee W, Zeng X, Rotolo K, Yang M, Schofield CJ, Bennett V, Yang W, Marszalek PE.

Biophys J. 2012 Mar 7;102(5):1118-26. doi: 10.1016/j.bpj.2012.01.046. Epub 2012 Mar 6.

3.

The study of pH-dependent stability shows that the TPLH-mediated hydrogen-bonding network is important for the conformation and stability of human gankyrin.

Yuan C, Guo Y, Zhu L, Guo W, Mahajan A, Weghorst CM, Li J.

Biochemistry. 2013 Jul 16;52(28):4848-57. doi: 10.1021/bi4005717. Epub 2013 Jul 8.

4.

Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins.

Guo Y, Yuan C, Tian F, Huang K, Weghorst CM, Tsai MD, Li J.

J Mol Biol. 2010 May 28;399(1):168-81. doi: 10.1016/j.jmb.2010.04.010. Epub 2010 Apr 14.

5.

Low frequency of ankyrin mutations in hereditary spherocytosis: identification of three novel mutations.

Leite RC, Basseres DS, Ferreira JS, Alberto FL, Costa FF, Saad ST.

Hum Mutat. 2000 Dec;16(6):529.

PMID:
11102985
6.

Mutation and modeling analysis of the Saccharomyces cerevisiae Swi6 ankyrin repeats.

Ewaskow SP, Sidorova JM, Hendle J, Emery JC, Lycan DE, Zhang KY, Breeden LL.

Biochemistry. 1998 Mar 31;37(13):4437-50.

PMID:
9521763
7.

Mechanical unfolding of an ankyrin repeat protein.

Serquera D, Lee W, Settanni G, Marszalek PE, Paci E, Itzhaki LS.

Biophys J. 2010 Apr 7;98(7):1294-301. doi: 10.1016/j.bpj.2009.12.4287.

8.

Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship.

Yuan C, Li J, Mahajan A, Poi MJ, Byeon IJ, Tsai MD.

Biochemistry. 2004 Sep 28;43(38):12152-61.

PMID:
15379554
9.

Long-range effects and functional consequences of stabilizing mutations in the ankyrin repeat domain of IκBα.

Cervantes CF, Handley LD, Sue SC, Dyson HJ, Komives EA.

J Mol Biol. 2013 Mar 11;425(5):902-13. doi: 10.1016/j.jmb.2012.12.012. Epub 2012 Dec 26.

10.

Comparisons of the conformational stability of cyclin-dependent kinase (CDK) 4-interacting ankyrin repeat (AR) proteins.

Guo Y, Mahajan A, Yuan C, Joo SH, Weghorst CM, Tsai MD, Li J.

Biochemistry. 2009 May 19;48(19):4050-62. doi: 10.1021/bi802247p.

PMID:
19320462
11.

Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding.

Johnson CP, Gaetani M, Ortiz V, Bhasin N, Harper S, Gallagher PG, Speicher DW, Discher DE.

Blood. 2007 Apr 15;109(8):3538-43. Epub 2006 Dec 27.

12.

Single-molecule FRET reveals the native-state dynamics of the IκBα ankyrin repeat domain.

Lamboy JA, Kim H, Dembinski H, Ha T, Komives EA.

J Mol Biol. 2013 Jul 24;425(14):2578-90. doi: 10.1016/j.jmb.2013.04.015. Epub 2013 Apr 22.

13.

Characterization and further stabilization of designed ankyrin repeat proteins by combining molecular dynamics simulations and experiments.

Interlandi G, Wetzel SK, Settanni G, Plückthun A, Caflisch A.

J Mol Biol. 2008 Jan 18;375(3):837-54. Epub 2007 Sep 21.

14.
15.

Nanospring behaviour of ankyrin repeats.

Lee G, Abdi K, Jiang Y, Michaely P, Bennett V, Marszalek PE.

Nature. 2006 Mar 9;440(7081):246-9. Epub 2006 Jan 15.

PMID:
16415852
16.

Full reconstruction of a vectorial protein folding pathway by atomic force microscopy and molecular dynamics simulations.

Lee W, Zeng X, Zhou HX, Bennett V, Yang W, Marszalek PE.

J Biol Chem. 2010 Dec 3;285(49):38167-72. doi: 10.1074/jbc.M110.179697. Epub 2010 Sep 24. Erratum in: J Biol Chem. 2011 Mar 11;286(10):8708.

17.

Molecular dynamics study of the stabilities of consensus designed ankyrin repeat proteins.

Yu H, Kohl A, Binz HK, Plückthun A, Grütter MG, van Gunsteren WF.

Proteins. 2006 Nov 1;65(2):285-95.

PMID:
16948156
18.

Spectrin oligomerization is cooperatively coupled to membrane assembly: a linkage targeted by many hereditary hemolytic anemias?

Giorgi M, Cianci CD, Gallagher PG, Morrow JS.

Exp Mol Pathol. 2001 Jun;70(3):215-30.

PMID:
11418000
19.

In silico structural and functional analysis of fragments of the ankyrin repeat protein p18(INK4c).

Sklenovsý P, Otyepka M.

J Biomol Struct Dyn. 2010 Feb;27(4):521-40.

PMID:
19916573
20.

Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins.

Binz HK, Stumpp MT, Forrer P, Amstutz P, Plückthun A.

J Mol Biol. 2003 Sep 12;332(2):489-503.

PMID:
12948497

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