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Items: 1 to 20 of 87

1.

p27kip1 protein levels reflect a nexus of oncogenic signaling during cell transformation.

Miller JP, Yeh N, Hofstetter CP, Keskin D, Goldstein AS, Koff A.

J Biol Chem. 2012 Jun 8;287(24):19775-85. doi: 10.1074/jbc.M112.361972. Epub 2012 Apr 17.

2.

Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen.

Kwun HJ, Shuda M, Camacho CJ, Gamper AM, Thant M, Chang Y, Moore PS.

J Virol. 2015 Apr;89(8):4191-200. doi: 10.1128/JVI.00157-15. Epub 2015 Jan 28.

3.
4.

PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigen.

Kotadia S, Kao LR, Comerford SA, Jones RT, Hammer RE, Megraw TL.

Oncogene. 2008 Oct 23;27(49):6334-46. doi: 10.1038/onc.2008.254. Epub 2008 Jul 28.

5.

Signaling and transcriptional changes critical for transformation of human cells by simian virus 40 small tumor antigen or protein phosphatase 2A B56gamma knockdown.

Moreno CS, Ramachandran S, Ashby DG, Laycock N, Plattner CA, Chen W, Hahn WC, Pallas DC.

Cancer Res. 2004 Oct 1;64(19):6978-88.

6.

PP2A inactivation is a crucial step in triggering apoptin-induced tumor-selective cell killing.

Zimmerman R, Peng DJ, Lanz H, Zhang YH, Danen-Van Oorschot A, Qu S, Backendorf C, Noteborn M.

Cell Death Dis. 2012 Apr 5;3:e291. doi: 10.1038/cddis.2012.31.

7.
8.

The p110alpha isoform of phosphatidylinositol 3-kinase is essential for polyomavirus middle T antigen-mediated transformation.

Utermark T, Schaffhausen BS, Roberts TM, Zhao JJ.

J Virol. 2007 Jul;81(13):7069-76. Epub 2007 Apr 18.

9.

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.

Yeh E, Cunningham M, Arnold H, Chasse D, Monteith T, Ivaldi G, Hahn WC, Stukenberg PT, Shenolikar S, Uchida T, Counter CM, Nevins JR, Means AR, Sears R.

Nat Cell Biol. 2004 Apr;6(4):308-18. Epub 2004 Mar 14.

PMID:
15048125
10.

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator.

Shuda M, Kwun HJ, Feng H, Chang Y, Moore PS.

J Clin Invest. 2011 Sep;121(9):3623-34. doi: 10.1172/JCI46323. Epub 2011 Aug 15.

11.

SV40 small T antigen and PP2A phosphatase in cell transformation.

Sablina AA, Hahn WC.

Cancer Metastasis Rev. 2008 Jun;27(2):137-46. doi: 10.1007/s10555-008-9116-0. Review.

PMID:
18214640
12.
13.

Cellular targets of the SV40 small-t antigen in human cell transformation.

Skoczylas C, Fahrbach KM, Rundell K.

Cell Cycle. 2004 May;3(5):606-10. Epub 2004 May 9. Review.

PMID:
15034297
14.

SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation.

Ahuja D, Sáenz-Robles MT, Pipas JM.

Oncogene. 2005 Nov 21;24(52):7729-45. Review.

PMID:
16299533
15.

SV40 early genes induce neoplastic properties in serous borderline ovarian tumor cells.

Woo MM, Salamanca CM, Symowicz J, Stack MS, Miller DM, Leung PC, Gilks CB, Auersperg N.

Gynecol Oncol. 2008 Oct;111(1):125-31. doi: 10.1016/j.ygyno.2008.06.021. Epub 2008 Aug 3.

PMID:
18678400
16.

Modified p27 Kip1 is efficient in suppressing HER2-mediated tumorigenicity.

Yang HY, Yang H, Zhao R, Lee MH.

J Cell Biochem. 2006 May 1;98(1):128-38.

PMID:
16365885
17.

Regulation of cell adhesion by PP2A and SV40 small tumor antigen: an important link to cell transformation.

Sontag JM, Sontag E.

Cell Mol Life Sci. 2006 Dec;63(24):2979-91. Review.

PMID:
17072501
18.

SV40 early region oncoproteins and human cell transformation.

Chen W, Hahn WC.

Histol Histopathol. 2003 Apr;18(2):541-50. doi: 10.14670/HH-18.541. Review.

PMID:
12647805
19.
20.

Inactivation of p27kip1 promotes chemical hepatocarcinogenesis through enhancing inflammatory cytokine secretion and STAT3 signaling activation.

Guo J, Ma Q, Zhou X, Fan P, Shan T, Miao D.

J Cell Physiol. 2013 Oct;228(10):1967-76. doi: 10.1002/jcp.24357.

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