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Items: 1 to 20 of 117

1.

Inhibition of type I interferon-mediated antiviral action in human glioma cells by the IKK inhibitors BMS-345541 and TPCA-1.

Du Z, Whitt MA, Baumann J, Garner JM, Morton CL, Davidoff AM, Pfeffer LM.

J Interferon Cytokine Res. 2012 Aug;32(8):368-77. doi: 10.1089/jir.2012.0002.

2.

Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1.

Cataldi M, Shah NR, Felt SA, Grdzelishvili VZ.

Virology. 2015 Nov;485:340-54. doi: 10.1016/j.virol.2015.08.003.

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IkappaB kinase-2-independent and -dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic.

Birrell MA, Wong S, Hardaker EL, Catley MC, McCluskie K, Collins M, Haj-Yahia S, Belvisi MG.

Mol Pharmacol. 2006 Jun;69(6):1791-800.

6.

The IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors.

Rauert-Wunderlich H, Siegmund D, Maier E, Giner T, Bargou RC, Wajant H, Stühmer T.

PLoS One. 2013;8(3):e59292. doi: 10.1371/journal.pone.0059292.

7.

Quercetin potentiates TNF-induced antiviral activity.

Ohnishi E, Bannai H.

Antiviral Res. 1993 Dec;22(4):327-31.

PMID:
8279819
8.

Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production.

Tsai J, Zhang R, Qiu W, Su Q, Naples M, Adeli K.

Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1287-98. doi: 10.1152/ajpgi.90540.2008.

9.

Antiviral activity of limitin against encephalomyocarditis virus, herpes simplex virus, and mouse hepatitis virus: diverse requirements by limitin and alpha interferon for interferon regulatory factor 1.

Kawamoto S, Oritani K, Asada H, Takahashi I, Ishikawa J, Yoshida H, Yamada M, Ishida N, Ujiie H, Masaie H, Tomiyama Y, Matsuzawa Y.

J Virol. 2003 Sep;77(17):9622-31.

10.

Activity of the selective IκB kinase inhibitor BMS-345541 against T-cell acute lymphoblastic leukemia: involvement of FOXO3a.

Buontempo F, Chiarini F, Bressanin D, Tabellini G, Melchionda F, Pession A, Fini M, Neri LM, McCubrey JA, Martelli AM.

Cell Cycle. 2012 Jul 1;11(13):2467-75. doi: 10.4161/cc.20859.

PMID:
22713244
11.

TPCA-1 is a direct dual inhibitor of STAT3 and NF-κB and regresses mutant EGFR-associated human non-small cell lung cancers.

Nan J, Du Y, Chen X, Bai Q, Wang Y, Zhang X, Zhu N, Zhang J, Hou J, Wang Q, Yang J.

Mol Cancer Ther. 2014 Mar;13(3):617-29. doi: 10.1158/1535-7163.MCT-13-0464.

12.

Histone deacetylase inhibitors potentiate vesicular stomatitis virus oncolysis in prostate cancer cells by modulating NF-κB-dependent autophagy.

Shulak L, Beljanski V, Chiang C, Dutta SM, Van Grevenynghe J, Belgnaoui SM, Nguyên TL, Di Lenardo T, Semmes OJ, Lin R, Hiscott J.

J Virol. 2014 Mar;88(5):2927-40. doi: 10.1128/JVI.03406-13.

13.

Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-kappaB Pathway.

Li J, Gong LY, Song LB, Jiang LL, Liu LP, Wu J, Yuan J, Cai JC, He M, Wang L, Zeng M, Cheng SY, Li M.

Am J Pathol. 2010 Feb;176(2):699-709. doi: 10.2353/ajpath.2010.090502.

14.

BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.

Burke JR, Pattoli MA, Gregor KR, Brassil PJ, MacMaster JF, McIntyre KW, Yang X, Iotzova VS, Clarke W, Strnad J, Qiu Y, Zusi FC.

J Biol Chem. 2003 Jan 17;278(3):1450-6.

15.

The role of IkappaB kinase 2, but not activation of NF-kappaB, in the release of CXCR3 ligands from IFN-gamma-stimulated human bronchial epithelial cells.

Tudhope SJ, Catley MC, Fenwick PS, Russell RE, Rumsey WL, Newton R, Barnes PJ, Donnelly LE.

J Immunol. 2007 Nov 1;179(9):6237-45.

16.

Targeting IKK/NF-κB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats.

Han X, Lu M, Wang S, Lv D, Liu H.

Neurosci Lett. 2012 Mar 5;511(1):28-32. doi: 10.1016/j.neulet.2012.01.030.

PMID:
22289688
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19.

Role of the vaccinia virus E3L and K3L gene products in rescue of VSV and EMCV from the effects of IFN-alpha.

Shors ST, Beattie E, Paoletti E, Tartaglia J, Jacobs BL.

J Interferon Cytokine Res. 1998 Sep;18(9):721-9.

PMID:
9781811
20.

Inhibition by a selective IkappaB kinase-2 inhibitor of interleukin-1-induced collagen degradation by corneal fibroblasts in three-dimensional culture.

Kondo Y, Fukuda K, Adachi T, Nishida T.

Invest Ophthalmol Vis Sci. 2008 Nov;49(11):4850-7. doi: 10.1167/iovs.08-1897.

PMID:
18676628
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