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Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid.

Duran-Vilaregut J, Manich G, Del Valle J, Camins A, Pallàs M, Vilaplana J, Pelegrí C.

J Neurosci Res. 2012 Sep;90(9):1803-13. doi: 10.1002/jnr.23060. Epub 2012 Apr 14.


Activation of Akt/GSK-3beta/beta-catenin signaling pathway is involved in survival of neurons after traumatic brain injury in rats.

Zhao S, Fu J, Liu X, Wang T, Zhang J, Zhao Y.

Neurol Res. 2012 May;34(4):400-7. doi: 10.1179/1743132812Y.0000000025.


Ionizing radiation can induce GSK-3beta phosphorylation and NF-kappaB transcriptional transactivation in ATM-deficient fibroblasts.

Kwon O, Kim KA, He L, Kim SO, Kim MS, Cha EY, Yoon BD, Sok DE, Jung M, Ahn JS, Kim BY.

Cell Signal. 2008 Apr;20(4):602-12. doi: 10.1016/j.cellsig.2007.10.022. Epub 2007 Nov 6.


Silibinin up-regulates DNA-protein kinase-dependent p53 activation to enhance UVB-induced apoptosis in mouse epithelial JB6 cells.

Dhanalakshmi S, Agarwal C, Singh RP, Agarwal R.

J Biol Chem. 2005 May 27;280(21):20375-83. Epub 2005 Mar 25.


DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.

An J, Huang YC, Xu QZ, Zhou LJ, Shang ZF, Huang B, Wang Y, Liu XD, Wu DC, Zhou PK.

BMC Mol Biol. 2010 Mar 6;11:18. doi: 10.1186/1471-2199-11-18.


Neuroprotective effect of hemeoxygenase-1/glycogen synthase kinase-3β modulators in 3-nitropropionic acid-induced neurotoxicity in rats.

Khan A, Jamwal S, Bijjem KR, Prakash A, Kumar P.

Neuroscience. 2015 Feb 26;287:66-77. doi: 10.1016/j.neuroscience.2014.12.018. Epub 2014 Dec 20.


Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells.

Li Y, Xiong H, Yang DQ.

Chin J Cancer. 2012 Aug;31(8):364-72. doi: 10.5732/cjc.012.10086. Epub 2012 Jun 26.


Atorvastatin attenuates mitochondrial toxin-induced striatal degeneration, with decreasing iNOS/c-Jun levels and activating ERK/Akt pathways.

Lee ST, Chu K, Park JE, Hong NH, Im WS, Kang L, Han Z, Jung KH, Kim MW, Kim M.

J Neurochem. 2008 Mar;104(5):1190-200. Epub 2007 Nov 1.


Regulation of GSK-3beta by calpain in the 3-nitropropionic acid model.

Crespo-Biel N, Camins A, Gutiérrez-Cuesta J, Melchiorri D, Nicoletti F, Pallàs M, Canudas AM.

Hippocampus. 2010 Aug;20(8):962-70. doi: 10.1002/hipo.20691.


Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway.

Chiu YJ, Hour MJ, Lu CC, Chung JG, Kuo SC, Huang WW, Chen HJ, Jin YA, Yang JS.

J Orthop Res. 2011 Sep;29(9):1448-56. doi: 10.1002/jor.21398. Epub 2011 Mar 21.


Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.

Brew CT, Aronchik I, Hsu JC, Sheen JH, Dickson RB, Bjeldanes LF, Firestone GL.

Int J Cancer. 2006 Feb 15;118(4):857-68.


Immunohistochemical study of p53-associated proteins in rat brain following lithium-pilocarpine status epilepticus.

Tan Z, Sankar R, Tu W, Shin D, Liu H, Wasterlain CG, Schreiber SS.

Brain Res. 2002 Mar 1;929(1):129-38.


Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells.

Gines S, Ivanova E, Seong IS, Saura CA, MacDonald ME.

J Biol Chem. 2003 Dec 12;278(50):50514-22. Epub 2003 Oct 1.


Activation of the Akt/GSK3beta signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats.

Endo H, Nito C, Kamada H, Nishi T, Chan PH.

J Cereb Blood Flow Metab. 2006 Dec;26(12):1479-89. Epub 2006 Mar 15.


Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death.

Tian B, Yang Q, Mao Z.

Nat Cell Biol. 2009 Feb;11(2):211-8. doi: 10.1038/ncb1829. Epub 2009 Jan 18. Erratum in: Nat Cell Biol. 2009 Aug;11(8);1042.


Lack of ataxia telangiectasia mutated kinase induces structural and functional changes in the heart: role in β-adrenergic receptor-stimulated apoptosis.

Foster CR, Zha Q, Daniel LL, Singh M, Singh K.

Exp Physiol. 2012 Apr;97(4):506-15. doi: 10.1113/expphysiol.2011.061812. Epub 2011 Dec 16.


UVB-Induced p21 degradation promotes apoptosis of human keratinocytes.

Lei X, Liu B, Han W, Ming M, He YY.

Photochem Photobiol Sci. 2010 Dec;9(12):1640-8. doi: 10.1039/c0pp00244e. Epub 2010 Oct 8.


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