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Items: 1 to 20 of 309

1.

Glomerular VEGF resistance induced by PKCδ/SHP-1 activation and contribution to diabetic nephropathy.

Mima A, Kitada M, Geraldes P, Li Q, Matsumoto M, Mizutani K, Qi W, Li C, Leitges M, Rask-Madsen C, King GL.

FASEB J. 2012 Jul;26(7):2963-74. doi: 10.1096/fj.11-202994. Epub 2012 Apr 12.

2.

Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy.

Geraldes P, Hiraoka-Yamamoto J, Matsumoto M, Clermont A, Leitges M, Marette A, Aiello LP, Kern TS, King GL.

Nat Med. 2009 Nov;15(11):1298-306. doi: 10.1038/nm.2052. Epub 2009 Nov 1.

3.

Expression of SHP-1 induced by hyperglycemia prevents insulin actions in podocytes.

Drapeau N, Lizotte F, Denhez B, Guay A, Kennedy CR, Geraldes P.

Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1188-98. doi: 10.1152/ajpendo.00560.2012. Epub 2013 Mar 26.

4.

Increased SHP-1 protein expression by high glucose levels reduces nephrin phosphorylation in podocytes.

Denhez B, Lizotte F, Guimond MO, Jones N, Takano T, Geraldes P.

J Biol Chem. 2015 Jan 2;290(1):350-8. doi: 10.1074/jbc.M114.612721. Epub 2014 Nov 17.

5.

Transgenic overexpression of GLUT1 in mouse glomeruli produces renal disease resembling diabetic glomerulosclerosis.

Wang Y, Heilig K, Saunders T, Minto A, Deb DK, Chang A, Brosius F, Monteiro C, Heilig CW.

Am J Physiol Renal Physiol. 2010 Jul;299(1):F99-F111. doi: 10.1152/ajprenal.00466.2009. Epub 2010 Apr 7.

6.

PKCdelta regulates the stimulation of vascular endothelial factor mRNA translation by angiotensin II through hnRNP K.

Sataranatarajan K, Lee MJ, Mariappan MM, Feliers D.

Cell Signal. 2008 May;20(5):969-77. doi: 10.1016/j.cellsig.2008.01.016. Epub 2008 Feb 1.

7.

PKCδ impaired vessel formation and angiogenic factor expression in diabetic ischemic limbs.

Lizotte F, Paré M, Denhez B, Leitges M, Guay A, Geraldes P.

Diabetes. 2013 Aug;62(8):2948-57. doi: 10.2337/db12-1432. Epub 2013 Apr 4.

8.

Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice.

Ku CH, White KE, Dei Cas A, Hayward A, Webster Z, Bilous R, Marshall S, Viberti G, Gnudi L.

Diabetes. 2008 Oct;57(10):2824-33. doi: 10.2337/db08-0647. Epub 2008 Jul 22.

9.

Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulated podocytes.

Kang SW, Natarajan R, Shahed A, Nast CC, LaPage J, Mundel P, Kashtan C, Adler SG.

J Am Soc Nephrol. 2003 Dec;14(12):3178-87.

10.
11.

eNOS deficiency predisposes podocytes to injury in diabetes.

Yuen DA, Stead BE, Zhang Y, White KE, Kabir MG, Thai K, Advani SL, Connelly KA, Takano T, Zhu L, Cox AJ, Kelly DJ, Gibson IW, Takahashi T, Harris RC, Advani A.

J Am Soc Nephrol. 2012 Nov;23(11):1810-23. doi: 10.1681/ASN.2011121170. Epub 2012 Sep 20.

12.

Mesenchymal stem cells ameliorate podocyte injury and proteinuria in a type 1 diabetic nephropathy rat model.

Wang S, Li Y, Zhao J, Zhang J, Huang Y.

Biol Blood Marrow Transplant. 2013 Apr;19(4):538-46. doi: 10.1016/j.bbmt.2013.01.001. Epub 2013 Jan 4.

13.

[The effects of VEGF-R inhibitor on podocytopathy of rats with type I diabetic nephropathy].

Wang S, Li Y, Huang YJ.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2011 Sep;27(9):1003-6. Chinese.

PMID:
21906476
14.
15.

Differential regulation of early growth response gene-1 expression by insulin and glucose in vascular endothelial cells.

Hasan RN, Phukan S, Harada S.

Arterioscler Thromb Vasc Biol. 2003 Jun 1;23(6):988-93. Epub 2003 Apr 10.

16.

Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease.

Veron D, Reidy KJ, Bertuccio C, Teichman J, Villegas G, Jimenez J, Shen W, Kopp JB, Thomas DB, Tufro A.

Kidney Int. 2010 Jun;77(11):989-99. doi: 10.1038/ki.2010.64. Epub 2010 Mar 10.

17.

Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus.

Veron D, Villegas G, Aggarwal PK, Bertuccio C, Jimenez J, Velazquez H, Reidy K, Abrahamson DR, Moeckel G, Kashgarian M, Tufro A.

PLoS One. 2012;7(7):e40589. doi: 10.1371/journal.pone.0040589. Epub 2012 Jul 13.

18.

Regulation of macrophage nitric oxide production by the protein tyrosine phosphatase Src homology 2 domain phosphotyrosine phosphatase 1 (SHP-1).

Blanchette J, Abu-Dayyeh I, Hassani K, Whitcombe L, Olivier M.

Immunology. 2009 May;127(1):123-33. doi: 10.1111/j.1365-2567.2008.02929.x.

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20.

Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model.

Ichinose K, Maeshima Y, Yamamoto Y, Kitayama H, Takazawa Y, Hirokoshi K, Sugiyama H, Yamasaki Y, Eguchi K, Makino H.

Diabetes. 2005 Oct;54(10):2891-903. Erratum in: Diabetes. 2006 Sep;55(9):2665.

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