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ALEX1 suppresses colony formation ability of human colorectal carcinoma cell lines.

Iseki H, Takeda A, Andoh T, Kuwabara K, Takahashi N, Kurochkin IV, Ishida H, Okazaki Y, Koyama I.

Cancer Sci. 2012 Jul;103(7):1267-71. doi: 10.1111/j.1349-7006.2012.02300.x. Epub 2012 May 17.


Human Arm protein lost in epithelial cancers, on chromosome X 1 (ALEX1) gene is transcriptionally regulated by CREB and Wnt/beta-catenin signaling.

Iseki H, Takeda A, Andoh T, Takahashi N, Kurochkin IV, Yarmishyn A, Shimada H, Okazaki Y, Koyama I.

Cancer Sci. 2010 Jun;101(6):1361-6. doi: 10.1111/j.1349-7006.2010.01541.x. Epub 2010 Feb 24.


ALEX1 Regulates Proliferation and Apoptosis in Breast Cancer Cells.

Gao Y, Wu JY, Zeng F, Liu GL, Zhang HT, Yun H, Song FZ.

Asian Pac J Cancer Prev. 2015;16(8):3293-9.


ALEX1 may be a novel biomarker for human cervical squamous cell carcinoma.

Zeng F, Liao K, Wu J, Gao Y, Li H, Fan J, Zhang H, Li Y, Bai X, Liu G, Song F.

Int J Clin Exp Pathol. 2015 Aug 1;8(8):9434-9. eCollection 2015.


ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.

Kurochkin IV, Yonemitsu N, Funahashi SI, Nomura H.

Biochem Biophys Res Commun. 2001 Jan 12;280(1):340-7.


Mapping of a candidate colorectal cancer tumor-suppressor gene to a 900-kilobase region on the short arm of chromosome 8.

Flanagan JM, Healey S, Young J, Whitehall V, Trott DA, Newbold RF, Chenevix-Trench G.

Genes Chromosomes Cancer. 2004 Jul;40(3):247-60.


DNA hypomethylation at the CpG island is involved in aberrant expression of the L1 cell adhesion molecule gene in colorectal cancer.

Kato K, Maesawa C, Itabashi T, Fujisawa K, Otsuka K, Kanno S, Tada H, Tatemichi Y, Kotani K, Oikawa H, Sugai T, Wakabayashi G, Masuda T.

Int J Oncol. 2009 Sep;35(3):467-76.


N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer.

Melotte V, Lentjes MH, van den Bosch SM, Hellebrekers DM, de Hoon JP, Wouters KA, Daenen KL, Partouns-Hendriks IE, Stessels F, Louwagie J, Smits KM, Weijenberg MP, Sanduleanu S, Khalid-de Bakker CA, Oort FA, Meijer GA, Jonkers DM, Herman JG, de Bruïne AP, van Engeland M.

J Natl Cancer Inst. 2009 Jul 1;101(13):916-27. doi: 10.1093/jnci/djp131. Epub 2009 Jun 17.


Frequent alteration of XAF1 in human colorectal cancers: implication for tumor cell resistance to apoptotic stresses.

Chung SK, Lee MG, Ryu BK, Lee JH, Han J, Byun DS, Chae KS, Lee KY, Jang JY, Kim HJ, Chi SG.

Gastroenterology. 2007 Jun;132(7):2459-77. Epub 2007 Apr 15.


Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation.

Lessi F, Beggs A, de Palo M, Anti M, Macarone Palmieri R, Francesconi S, Gomes V, Bevilacqua G, Tomlinson I, Segditsas S.

PLoS One. 2010 Nov 5;5(11):e13840. doi: 10.1371/journal.pone.0013840.


Epigenetic alteration of PRKCDBP in colorectal cancers and its implication in tumor cell resistance to TNFα-induced apoptosis.

Lee JH, Kang MJ, Han HY, Lee MG, Jeong SI, Ryu BK, Ha TK, Her NG, Han J, Park SJ, Lee KY, Kim HJ, Chi SG.

Clin Cancer Res. 2011 Dec 15;17(24):7551-62. doi: 10.1158/1078-0432.CCR-11-1026. Epub 2011 Oct 6.


Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas.

Toyooka S, Toyooka KO, Harada K, Miyajima K, Makarla P, Sathyanarayana UG, Yin J, Sato F, Shivapurkar N, Meltzer SJ, Gazdar AF.

Cancer Res. 2002 Jun 15;62(12):3382-6.


Knockdown of RAGE expression inhibits colorectal cancer cell invasion and suppresses angiogenesis in vitro and in vivo.

Liang H, Zhong Y, Zhou S, Peng L.

Cancer Lett. 2011 Dec 26;313(1):91-8. doi: 10.1016/j.canlet.2011.08.028. Epub 2011 Sep 6.


HOP/OB1/NECC1 promoter DNA is frequently hypermethylated and involved in tumorigenic ability in esophageal squamous cell carcinoma.

Yamashita K, Kim MS, Park HL, Tokumaru Y, Osada M, Inoue H, Mori M, Sidransky D.

Mol Cancer Res. 2008 Jan;6(1):31-41. doi: 10.1158/1541-7786.MCR-07-0213.


ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma.

Götze S, Feldhaus V, Traska T, Wolter M, Reifenberger G, Tannapfel A, Kuhnen C, Martin D, Müller O, Sievers S.

BMC Cancer. 2009 Dec 17;9:447. doi: 10.1186/1471-2407-9-447.


GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.

Hellebrekers DM, Lentjes MH, van den Bosch SM, Melotte V, Wouters KA, Daenen KL, Smits KM, Akiyama Y, Yuasa Y, Sanduleanu S, Khalid-de Bakker CA, Jonkers D, Weijenberg MP, Louwagie J, van Criekinge W, Carvalho B, Meijer GA, Baylin SB, Herman JG, de Bruïne AP, van Engeland M.

Clin Cancer Res. 2009 Jun 15;15(12):3990-7. doi: 10.1158/1078-0432.CCR-09-0055. Epub 2009 Jun 9.


Overexpression of bone morphogenetic protein 4 enhances the invasiveness of Smad4-deficient human colorectal cancer cells.

Deng H, Ravikumar TS, Yang WL.

Cancer Lett. 2009 Aug 28;281(2):220-31. doi: 10.1016/j.canlet.2009.02.046. Epub 2009 Mar 24.


MPP3 inactivation by promoter CpG islands hypermethylation in colorectal carcinogenesis.

Feng X, Chen K, Ye S, Wang H, Wei G, Tan W, Cheng S, Zhang Y, Liu S, Zhou Y.

Cancer Biomark. 2012;11(2-3):99-106.


DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines.

Roll JD, Rivenbark AG, Jones WD, Coleman WB.

Mol Cancer. 2008 Jan 25;7:15. doi: 10.1186/1476-4598-7-15.

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