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Items: 1 to 20 of 128

1.

Reduced calreticulin levels link endoplasmic reticulum stress and Fas-triggered cell death in motoneurons vulnerable to ALS.

Bernard-Marissal N, Moumen A, Sunyach C, Pellegrino C, Dudley K, Henderson CE, Raoul C, Pettmann B.

J Neurosci. 2012 Apr 4;32(14):4901-12. doi: 10.1523/JNEUROSCI.5431-11.2012.

2.

Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice.

Bernard-Marissal N, Sunyach C, Marissal T, Raoul C, Pettmann B.

Neurobiol Dis. 2015 Jan;73:130-6. doi: 10.1016/j.nbd.2014.09.009. Epub 2014 Sep 30.

PMID:
25277755
3.

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

Raoul C, Estévez AG, Nishimune H, Cleveland DW, deLapeyrière O, Henderson CE, Haase G, Pettmann B.

Neuron. 2002 Sep 12;35(6):1067-83.

4.

Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death.

Duplan L, Bernard N, Casseron W, Dudley K, Thouvenot E, Honnorat J, Rogemond V, De Bovis B, Aebischer P, Marin P, Raoul C, Henderson CE, Pettmann B.

J Neurosci. 2010 Jan 13;30(2):785-96. doi: 10.1523/JNEUROSCI.5411-09.2010.

5.

Fas small interfering RNA reduces motoneuron death in amyotrophic lateral sclerosis mice.

Locatelli F, Corti S, Papadimitriou D, Fortunato F, Del Bo R, Donadoni C, Nizzardo M, Nardini M, Salani S, Ghezzi S, Strazzer S, Bresolin N, Comi GP.

Ann Neurol. 2007 Jul;62(1):81-92.

PMID:
17503505
6.

Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice.

Kieran D, Woods I, Villunger A, Strasser A, Prehn JH.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20606-11. Epub 2007 Dec 11.

7.

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.

Beers DR, Henkel JS, Xiao Q, Zhao W, Wang J, Yen AA, Siklos L, McKercher SR, Appel SH.

Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):16021-6. Epub 2006 Oct 16.

8.

Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia.

Xiao Q, Zhao W, Beers DR, Yen AA, Xie W, Henkel JS, Appel SH.

J Neurochem. 2007 Sep;102(6):2008-19. Epub 2007 Jun 7.

9.

Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL.

Raoul C, Buhler E, Sadeghi C, Jacquier A, Aebischer P, Pettmann B, Henderson CE, Haase G.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):6007-12. Epub 2006 Mar 31.

10.

Extracellular mutant SOD1 induces microglial-mediated motoneuron injury.

Zhao W, Beers DR, Henkel JS, Zhang W, Urushitani M, Julien JP, Appel SH.

Glia. 2010 Jan 15;58(2):231-43. doi: 10.1002/glia.20919.

11.

Fas(t) balls and Lou Gehrig disease. A clue to selective vulnerability of motor neurons?

Xiong ZQ, McNamara JO.

Neuron. 2002 Sep 12;35(6):1011-3. Review.

12.

Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS.

Filézac de L'Etang A, Maharjan N, Cordeiro Braña M, Ruegsegger C, Rehmann R, Goswami A, Roos A, Troost D, Schneider BL, Weis J, Saxena S.

Nat Neurosci. 2015 Feb;18(2):227-38. doi: 10.1038/nn.3903. Epub 2015 Jan 5.

PMID:
25559081
14.

Axotomy-induced target disconnection promotes an additional death mechanism involved in motoneuron degeneration in amyotrophic lateral sclerosis transgenic mice.

Haulcomb MM, Mesnard NA, Batka RJ, Alexander TD, Sanders VM, Jones KJ.

J Comp Neurol. 2014 Jul 1;522(10):2349-76. doi: 10.1002/cne.23538.

15.

Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis.

Ferraiuolo L, Higginbottom A, Heath PR, Barber S, Greenald D, Kirby J, Shaw PJ.

Brain. 2011 Sep;134(Pt 9):2627-41. doi: 10.1093/brain/awr193.

16.
17.

IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1.

Aebischer J, Cassina P, Otsmane B, Moumen A, Seilhean D, Meininger V, Barbeito L, Pettmann B, Raoul C.

Cell Death Differ. 2011 May;18(5):754-68. doi: 10.1038/cdd.2010.143. Epub 2010 Nov 12.

19.
20.

Endoplasmic reticulum stress is accompanied by activation of NF-κB in amyotrophic lateral sclerosis.

Prell T, Lautenschläger J, Weidemann L, Ruhmer J, Witte OW, Grosskreutz J.

J Neuroimmunol. 2014 May 15;270(1-2):29-36. doi: 10.1016/j.jneuroim.2014.03.005. Epub 2014 Mar 12.

PMID:
24666819

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