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Items: 1 to 20 of 85

1.

Retraction: Defective heart development in hypomorphic LSD1 mice.

Nicholson TB, Su H, Hevi S, Wang J, Bajko J, Li M, Valdez R, Loureiro J, Cheng X, Li E, Kinzel B, Labow M, Chen T.

Cell Res. 2012 Apr 10. doi: 10.1038/cr.2012.60. [Epub ahead of print] No abstract available.

PMID:
22491473
2.

Defective heart development in hypomorphic LSD1 mice.

Nicholson TB, Su H, Hevi S, Wang J, Bajko J, Li M, Valdez R, Loureiro J, Cheng X, Li E, Kinzel B, Labow M, Chen T.

Cell Res. 2011 Dec 6. doi: 10.1038/cr.2011.194. [Epub ahead of print] Retraction in: Cell Res. 2012 Apr 10;:.

PMID:
22143567
3.

A hypomorphic lsd1 allele results in heart development defects in mice.

Nicholson TB, Singh AK, Su H, Hevi S, Wang J, Bajko J, Li M, Valdez R, Goetschkes M, Capodieci P, Loureiro J, Cheng X, Li E, Kinzel B, Labow M, Chen T.

PLoS One. 2013 Apr 24;8(4):e60913. doi: 10.1371/journal.pone.0060913. Print 2013.

4.

Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally.

Wasson JA, Simon AK, Myrick DA, Wolf G, Driscoll S, Pfaff SL, Macfarlan TS, Katz DJ.

Elife. 2016 Jan 27;5. pii: e08848. doi: 10.7554/eLife.08848.

5.

Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension.

Pojoga LH, Williams JS, Yao TM, Kumar A, Raffetto JD, do Nascimento GR, Reslan OM, Adler GK, Williams GH, Shi Y, Khalil RA.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1862-71. doi: 10.1152/ajpheart.00513.2011. Epub 2011 Aug 26.

6.

Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability.

Foster CT, Dovey OM, Lezina L, Luo JL, Gant TW, Barlev N, Bradley A, Cowley SM.

Mol Cell Biol. 2010 Oct;30(20):4851-63. doi: 10.1128/MCB.00521-10. Epub 2010 Aug 16.

7.

LSD1 demethylates histone and non-histone proteins.

Nicholson TB, Chen T.

Epigenetics. 2009 Apr 1;4(3):129-32. Epub 2009 Apr 14.

PMID:
19395867
8.

Histone Demethylase LSD1 Promotes Adipocyte Differentiation through Repressing Wnt Signaling.

Chen Y, Kim J, Zhang R, Yang X, Zhang Y, Fang J, Chen Z, Teng L, Chen X, Ge H, Atadja P, Li E, Chen T, Qi W.

Cell Chem Biol. 2016 Oct 20;23(10):1228-1240. doi: 10.1016/j.chembiol.2016.08.010. Epub 2016 Sep 15.

PMID:
27642069
9.

LSD1 modulates stress-evoked transcription of immediate early genes and emotional behavior.

Rusconi F, Grillo B, Ponzoni L, Bassani S, Toffolo E, Paganini L, Mallei A, Braida D, Passafaro M, Popoli M, Sala M, Battaglioli E.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3651-6. doi: 10.1073/pnas.1511974113. Epub 2016 Mar 14.

10.

Destabilizing LSD1 by Jade-2 promotes neurogenesis: an antibraking system in neural development.

Han X, Gui B, Xiong C, Zhao L, Liang J, Sun L, Yang X, Yu W, Si W, Yan R, Yi X, Zhang D, Li W, Li L, Yang J, Wang Y, Sun YE, Zhang D, Meng A, Shang Y.

Mol Cell. 2014 Aug 7;55(3):482-94. doi: 10.1016/j.molcel.2014.06.006. Epub 2014 Jul 10.

11.

Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem cells for malignant transformation.

Wada T, Koyama D, Kikuchi J, Honda H, Furukawa Y.

Blood. 2015 Jun 11;125(24):3731-46. doi: 10.1182/blood-2014-11-610907. Epub 2015 Apr 22.

12.

Reversible inhibitors of LSD1 as therapeutic agents in acute myeloid leukemia: clinical significance and progress to date.

Mould DP, McGonagle AE, Wiseman DH, Williams EL, Jordan AM.

Med Res Rev. 2015 May;35(3):586-618. doi: 10.1002/med.21334. Epub 2014 Nov 24. Review.

PMID:
25418875
13.

LSD1 sustains pancreatic cancer growth via maintaining HIF1α-dependent glycolytic process.

Qin Y, Zhu W, Xu W, Zhang B, Shi S, Ji S, Liu J, Long J, Liu C, Liu L, Xu J, Yu X.

Cancer Lett. 2014 Jun 1;347(2):225-32. doi: 10.1016/j.canlet.2014.02.013. Epub 2014 Feb 18.

PMID:
24561118
14.

Opposing LSD1 complexes function in developmental gene activation and repression programmes.

Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG, Krones A, Ohgi KA, Zhu P, Garcia-Bassets I, Liu F, Taylor H, Lozach J, Jayes FL, Korach KS, Glass CK, Fu XD, Rosenfeld MG.

Nature. 2007 Apr 19;446(7138):882-7. Epub 2007 Mar 28.

PMID:
17392792
15.

The LSD1 Family of Histone Demethylases and the Pumilio Posttranscriptional Repressor Function in a Complex Regulatory Feedback Loop.

Miles WO, Lepesant JM, Bourdeaux J, Texier M, Kerenyi MA, Nakakido M, Hamamoto R, Orkin SH, Dyson NJ, Di Stefano L.

Mol Cell Biol. 2015 Dec;35(24):4199-211. doi: 10.1128/MCB.00755-15. Epub 2015 Oct 5.

16.

Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer.

Feng J, Xu G, Liu J, Zhang N, Li L, Ji J, Zhang J, Zhang L, Wang G, Wang X, Tan J, Huang B, Lu J, Zhang Y.

Breast Cancer Res Treat. 2016 Oct;159(3):443-56. doi: 10.1007/s10549-016-3959-9. Epub 2016 Aug 29.

PMID:
27572339
17.

Involvement of histone demethylase LSD1 in short-time-scale gene expression changes during cell cycle progression in embryonic stem cells.

Nair VD, Ge Y, Balasubramaniyan N, Kim J, Okawa Y, Chikina M, Troyanskaya O, Sealfon SC.

Mol Cell Biol. 2012 Dec;32(23):4861-76. doi: 10.1128/MCB.00816-12. Epub 2012 Oct 1.

18.

Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties.

Wang J, Lu F, Ren Q, Sun H, Xu Z, Lan R, Liu Y, Ward D, Quan J, Ye T, Zhang H.

Cancer Res. 2011 Dec 1;71(23):7238-49. doi: 10.1158/0008-5472.CAN-11-0896. Epub 2011 Oct 5.

19.

Lysine-specific demethylase 1 expression in zebrafish during the early stages of neuronal development.

Li A, Sun Y, Dou C, Chen J, Zhang J.

Neural Regen Res. 2012 Dec 5;7(34):2719-26. doi: 10.3969/j.issn.1673-5374.2012.34.010.

20.

Phosphorylation of LSD1 by PKCα is crucial for circadian rhythmicity and phase resetting.

Nam HJ, Boo K, Kim D, Han DH, Choe HK, Kim CR, Sun W, Kim H, Kim K, Lee H, Metzger E, Schuele R, Yoo SH, Takahashi JS, Cho S, Son GH, Baek SH.

Mol Cell. 2014 Mar 6;53(5):791-805. doi: 10.1016/j.molcel.2014.01.028. Epub 2014 Feb 27.

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