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Items: 1 to 20 of 102

1.

An additional piece in the puzzle of neutrophil-derived IL-1β: the NLRP3 inflammasome.

Tamassia N, Zimmermann M, Cassatella MA.

Eur J Immunol. 2012 Mar;42(3):565-8. doi: 10.1002/eji.201242399.

2.

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.

Mankan AK, Dau T, Jenne D, Hornung V.

Eur J Immunol. 2012 Mar;42(3):710-5. doi: 10.1002/eji.201141921.

3.

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E.

J Immunol. 2015 Feb 15;194(4):1763-75. doi: 10.4049/jimmunol.1401624.

4.

Histones trigger sterile inflammation by activating the NLRP3 inflammasome.

Allam R, Darisipudi MN, Tschopp J, Anders HJ.

Eur J Immunol. 2013 Dec;43(12):3336-42. doi: 10.1002/eji.201243224.

5.

Shiga Toxins Activate the NLRP3 Inflammasome Pathway To Promote Both Production of the Proinflammatory Cytokine Interleukin-1β and Apoptotic Cell Death.

Lee MS, Kwon H, Lee EY, Kim DJ, Park JH, Tesh VL, Oh TK, Kim MH.

Infect Immun. 2015 Oct 26;84(1):172-86. doi: 10.1128/IAI.01095-15.

6.

Serum amyloid A induces NLRP-3-mediated IL-1β secretion in neutrophils.

Migita K, Izumi Y, Jiuchi Y, Kozuru H, Kawahara C, Nakamura M, Nakamura T, Agematsu K, Masumoto J, Yasunami M, Kawakami A, Eguchi K.

PLoS One. 2014 May 20;9(5):e96703. doi: 10.1371/journal.pone.0096703.

7.

The NLRP3 inflammasome is active but not essential in endotoxin-induced uveitis.

Rosenzweig HL, Woods A, Clowers JS, Planck SR, Rosenbaum JT.

Inflamm Res. 2012 Mar;61(3):225-31. doi: 10.1007/s00011-011-0404-8.

8.

Critical role for the NLRP3 inflammasome during acute lung injury.

Grailer JJ, Canning BA, Kalbitz M, Haggadone MD, Dhond RM, Andjelkovic AV, Zetoune FS, Ward PA.

J Immunol. 2014 Jun 15;192(12):5974-83. doi: 10.4049/jimmunol.1400368.

9.

A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB.

PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026.

10.

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.

Hu Y, Mao K, Zeng Y, Chen S, Tao Z, Yang C, Sun S, Wu X, Meng G, Sun B.

J Immunol. 2010 Dec 15;185(12):7699-705. doi: 10.4049/jimmunol.1001099.

11.

The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury.

Jones HD, Crother TR, Gonzalez-Villalobos RA, Jupelli M, Chen S, Dagvadorj J, Arditi M, Shimada K.

Am J Respir Cell Mol Biol. 2014 Feb;50(2):270-80. doi: 10.1165/rcmb.2013-0087OC.

12.

NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout.

Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, Souza DG, Teixeira MM.

Arthritis Rheum. 2012 Feb;64(2):474-84. doi: 10.1002/art.33355.

13.

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.

Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M.

PLoS Pathog. 2009 Aug;5(8):e1000559. doi: 10.1371/journal.ppat.1000559. Erratum in: PLoS Pathog. 2009 Sep;5(9). doi: 10.1371/annotation/abca067d-b82b-4de6-93c5-0fcc38e3df05. Tiemi Shio, Marina [corrected to Shio, Marina Tiemi].

14.

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.

Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V, Barberà-Cremades M, Yagüe J, Ruiz-Ortiz E, Antón J, Buján S, Couillin I, Brough D, Arostegui JI, Pelegrín P.

Nat Immunol. 2014 Aug;15(8):738-48. doi: 10.1038/ni.2919.

PMID:
24952504
15.

MicroRNA-133a-1 regulates inflammasome activation through uncoupling protein-2.

Bandyopadhyay S, Lane T, Venugopal R, Parthasarathy PT, Cho Y, Galam L, Lockey R, Kolliputi N.

Biochem Biophys Res Commun. 2013 Sep 27;439(3):407-12. doi: 10.1016/j.bbrc.2013.08.056.

16.

An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury.

Shigeoka AA, Mueller JL, Kambo A, Mathison JC, King AJ, Hall WF, Correia Jda S, Ulevitch RJ, Hoffman HM, McKay DB.

J Immunol. 2010 Nov 15;185(10):6277-85. doi: 10.4049/jimmunol.1002330. Erratum in: J Immunol. 2011 Feb 1;186(3):1880.

17.

Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection.

Silva GK, Costa RS, Silveira TN, Caetano BC, Horta CV, Gutierrez FR, Guedes PM, Andrade WA, De Niz M, Gazzinelli RT, Zamboni DS, Silva JS.

J Immunol. 2013 Sep 15;191(6):3373-83. doi: 10.4049/jimmunol.1203293.

18.

Follistatin-like protein 1 enhances NLRP3 inflammasome-mediated IL-1β secretion from monocytes and macrophages.

Chaly Y, Fu Y, Marinov A, Hostager B, Yan W, Campfield B, Kellum JA, Bushnell D, Wang Y, Vockley J, Hirsch R.

Eur J Immunol. 2014 May;44(5):1467-79. doi: 10.1002/eji.201344063.

19.

The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice.

Charmoy M, Hurrell BP, Romano A, Lee SH, Ribeiro-Gomes F, Riteau N, Mayer-Barber K, Tacchini-Cottier F, Sacks DL.

Eur J Immunol. 2016 Apr;46(4):897-911. doi: 10.1002/eji.201546015.

PMID:
26689285
20.

Lipopolysaccharide/adenosine triphosphate induces IL‑1β and IL-18 secretion through the NLRP3 inflammasome in RAW264.7 murine macrophage cells.

Xie Q, Shen WW, Zhong J, Huang C, Zhang L, Li J.

Int J Mol Med. 2014 Jul;34(1):341-9. doi: 10.3892/ijmm.2014.1755.

PMID:
24789624
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