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PHF19 and Akt control the switch between proliferative and invasive states in melanoma.

Ghislin S, Deshayes F, Middendorp S, Boggetto N, Alcaide-Loridan C.

Cell Cycle. 2012 Apr 15;11(8):1634-45. doi: 10.4161/cc.20095. Epub 2012 Apr 15.


Nanog and Oct4 overexpression increases motility and transmigration of melanoma cells.

Borrull A, Ghislin S, Deshayes F, Lauriol J, Alcaide-Loridan C, Middendorp S.

J Cancer Res Clin Oncol. 2012 Jul;138(7):1145-54. doi: 10.1007/s00432-012-1186-2. Epub 2012 Mar 11.


Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation.

Kumar SM, Liu S, Lu H, Zhang H, Zhang PJ, Gimotty PA, Guerra M, Guo W, Xu X.

Oncogene. 2012 Nov 22;31(47):4898-911. doi: 10.1038/onc.2011.656. Epub 2012 Jan 30.


Plasticity of melanoma cells induced by neural cell crest conditions and three-dimensional growth.

Ghislin S, Deshayes F, Lauriol J, Middendorp S, Martins I, Al-Daccak R, Alcaide-Loridan C.

Melanoma Res. 2012 Jun;22(3):184-94. doi: 10.1097/CMR.0b013e328351e7c4.


Gata4 blocks somatic cell reprogramming by directly repressing Nanog.

Serrano F, Calatayud CF, Blazquez M, Torres J, Castell JV, Bort R.

Stem Cells. 2013 Jan;31(1):71-82. doi: 10.1002/stem.1272.


Transcriptional regulation of nanog by OCT4 and SOX2.

Rodda DJ, Chew JL, Lim LH, Loh YH, Wang B, Ng HH, Robson P.

J Biol Chem. 2005 Jul 1;280(26):24731-7. Epub 2005 Apr 27.


Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function.

Ramgolam K, Lauriol J, Lalou C, Lauden L, Michel L, de la Grange P, Khatib AM, Aoudjit F, Charron D, Alcaide-Loridan C, Al-Daccak R.

PLoS One. 2011 Apr 15;6(4):e18784. doi: 10.1371/journal.pone.0018784.


Coordinated repressive chromatin-remodeling of Oct4 and Nanog genes in RA-induced differentiation of embryonic stem cells involves RIP140.

Wu CY, Feng X, Wei LN.

Nucleic Acids Res. 2014 Apr;42(7):4306-17. doi: 10.1093/nar/gku092. Epub 2014 Jan 30.


Akt suppresses DLK for maintaining self-renewal of mouse embryonic stem cells.

Wu CC, Wu HJ, Wang CH, Lin CH, Hsu SC, Chen YR, Hsiao M, Schuyler SC, Lu FL, Ma N, Lu J.

Cell Cycle. 2015;14(8):1207-17. doi: 10.1080/15384101.2015.1014144.


Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells.

Loh YH, Zhang W, Chen X, George J, Ng HH.

Genes Dev. 2007 Oct 15;21(20):2545-57.


Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells.

Sheik Mohamed J, Gaughwin PM, Lim B, Robson P, Lipovich L.

RNA. 2010 Feb;16(2):324-37. doi: 10.1261/rna.1441510. Epub 2009 Dec 21.


Zfp819, a novel KRAB-zinc finger protein, interacts with KAP1 and functions in genomic integrity maintenance of mouse embryonic stem cells.

Tan X, Xu X, Elkenani M, Smorag L, Zechner U, Nolte J, Engel W, Pantakani DV.

Stem Cell Res. 2013 Nov;11(3):1045-59. doi: 10.1016/j.scr.2013.07.006. Epub 2013 Jul 30.


Polycomb protein EED is required for silencing of pluripotency genes upon ESC differentiation.

Obier N, Lin Q, Cauchy P, Hornich V, Zenke M, Becker M, Müller AM.

Stem Cell Rev. 2015 Feb;11(1):50-61. doi: 10.1007/s12015-014-9550-z.


Reduced tumorigenicity and drug resistance through the downregulation of octamer-binding protein 4 and Nanog transcriptional factor expression in human breast stem cells.

Huang ZJ, You J, Luo WY, Chen BS, Feng QZ, Wu BL, Jiang L, Luo Q.

Mol Med Rep. 2015 Mar;11(3):1647-54. doi: 10.3892/mmr.2014.2972. Epub 2014 Nov 18.


KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells.

Chan KK, Zhang J, Chia NY, Chan YS, Sim HS, Tan KS, Oh SK, Ng HH, Choo AB.

Stem Cells. 2009 Sep;27(9):2114-25. doi: 10.1002/stem.143.


Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.

Sun LT, Yamaguchi S, Hirano K, Ichisaka T, Kuroda T, Tada T.

Dev Biol. 2014 Aug 15;392(2):182-92. doi: 10.1016/j.ydbio.2014.06.002. Epub 2014 Jun 12.


Zfp143 regulates Nanog through modulation of Oct4 binding.

Chen X, Fang F, Liou YC, Ng HH.

Stem Cells. 2008 Nov;26(11):2759-67. doi: 10.1634/stemcells.2008-0398. Epub 2008 Aug 7.


Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data.

Sharov AA, Masui S, Sharova LV, Piao Y, Aiba K, Matoba R, Xin L, Niwa H, Ko MS.

BMC Genomics. 2008 Jun 3;9:269. doi: 10.1186/1471-2164-9-269.


In vivo switching of human melanoma cells between proliferative and invasive states.

Hoek KS, Eichhoff OM, Schlegel NC, Döbbeling U, Kobert N, Schaerer L, Hemmi S, Dummer R.

Cancer Res. 2008 Feb 1;68(3):650-6. doi: 10.1158/0008-5472.CAN-07-2491.

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