Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 74

1.

The ubiquitin ligase Siah1 controls ELL2 stability and formation of super elongation complexes to modulate gene transcription.

Liu M, Hsu J, Chan C, Li Z, Zhou Q.

Mol Cell. 2012 May 11;46(3):325-34. doi: 10.1016/j.molcel.2012.03.007. Epub 2012 Apr 5.

2.

Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription.

Lu H, Li Z, Zhang W, Schulze-Gahmen U, Xue Y, Zhou Q.

Nucleic Acids Res. 2015 Jul 13;43(12):5868-79. doi: 10.1093/nar/gkv541. Epub 2015 May 24.

3.

HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.

He N, Liu M, Hsu J, Xue Y, Chou S, Burlingame A, Krogan NJ, Alber T, Zhou Q.

Mol Cell. 2010 May 14;38(3):428-38. doi: 10.1016/j.molcel.2010.04.013.

4.

Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.

He N, Chan CK, Sobhian B, Chou S, Xue Y, Liu M, Alber T, Benkirane M, Zhou Q.

Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):E636-45. doi: 10.1073/pnas.1107107108. Epub 2011 Aug 22.

5.

A Minor Subset of Super Elongation Complexes Plays a Predominant Role in Reversing HIV-1 Latency.

Li Z, Lu H, Zhou Q.

Mol Cell Biol. 2016 Feb 1;36(7):1194-205. doi: 10.1128/MCB.00994-15.

6.

AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter.

Schulze-Gahmen U, Lu H, Zhou Q, Alber T.

Elife. 2014 Apr 24;3:e02375. doi: 10.7554/eLife.02375.

7.

HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.

Chou S, Upton H, Bao K, Schulze-Gahmen U, Samelson AJ, He N, Nowak A, Lu H, Krogan NJ, Zhou Q, Alber T.

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):E123-31. doi: 10.1073/pnas.1216971110. Epub 2012 Dec 18.

8.

AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.

Lu H, Li Z, Xue Y, Schulze-Gahmen U, Johnson JR, Krogan NJ, Alber T, Zhou Q.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E15-24. doi: 10.1073/pnas.1318503111. Epub 2013 Dec 23.

9.

Stabilization of HIPK2 by escape from proteasomal degradation mediated by the E3 ubiquitin ligase Siah1.

Kim SY, Choi DW, Kim EA, Choi CY.

Cancer Lett. 2009 Jul 8;279(2):177-84. doi: 10.1016/j.canlet.2009.01.036. Epub 2009 Feb 27.

PMID:
19250734
10.

SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status.

Adam MG, Matt S, Christian S, Hess-Stumpp H, Haegebarth A, Hofmann TG, Algire C.

Cell Cycle. 2015;14(23):3734-47. doi: 10.1080/15384101.2015.1104441.

11.

The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output.

Luo Z, Lin C, Guest E, Garrett AS, Mohaghegh N, Swanson S, Marshall S, Florens L, Washburn MP, Shilatifard A.

Mol Cell Biol. 2012 Jul;32(13):2608-17. doi: 10.1128/MCB.00182-12. Epub 2012 Apr 30.

12.

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat.

Schulze-Gahmen U, Upton H, Birnberg A, Bao K, Chou S, Krogan NJ, Zhou Q, Alber T.

Elife. 2013 Mar 5;2:e00327. doi: 10.7554/eLife.00327.

13.

Transcription factor IIS cooperates with the E3 ligase UBR5 to ubiquitinate the CDK9 subunit of the positive transcription elongation factor B.

Cojocaru M, Bouchard A, Cloutier P, Cooper JJ, Varzavand K, Price DH, Coulombe B.

J Biol Chem. 2011 Feb 18;286(7):5012-22. doi: 10.1074/jbc.M110.176628. Epub 2010 Dec 2.

14.

Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription.

Qi S, Li Z, Schulze-Gahmen U, Stjepanovic G, Zhou Q, Hurley JH.

Nat Commun. 2017 Jan 30;8:14076. doi: 10.1038/ncomms14076.

15.

E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3.

Zhou Y, Li L, Liu Q, Xing G, Kuai X, Sun J, Yin X, Wang J, Zhang L, He F.

Cell Signal. 2008 May;20(5):942-8. doi: 10.1016/j.cellsig.2008.01.010. Epub 2008 Jan 24.

PMID:
18276110
16.

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.

Lin C, Smith ER, Takahashi H, Lai KC, Martin-Brown S, Florens L, Washburn MP, Conaway JW, Conaway RC, Shilatifard A.

Mol Cell. 2010 Feb 12;37(3):429-37. doi: 10.1016/j.molcel.2010.01.026.

17.

The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers.

Knauer SK, Mahendrarajah N, Roos WP, Krämer OH.

Cytokine Growth Factor Rev. 2015 Aug;26(4):405-13. doi: 10.1016/j.cytogfr.2015.04.002. Epub 2015 May 12. Review.

PMID:
26028498
18.

AFF1 and AFF4 differentially regulate the osteogenic differentiation of human MSCs.

Zhou CC, Xiong QC, Zhu XX, Du W, Deng P, Li XB, Jiang YZ, Zou SJ, Wang CY, Yuan Q.

Bone Res. 2017 Sep 26;5:17044. doi: 10.1038/boneres.2017.44. eCollection 2017.

19.

Investigating the molecular basis of Siah1 and Siah2 E3 ubiquitin ligase substrate specificity.

Gopalsamy A, Hagen T, Swaminathan K.

PLoS One. 2014 Sep 9;9(9):e106547. doi: 10.1371/journal.pone.0106547. eCollection 2014.

20.

Supplemental Content

Support Center