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Items: 1 to 20 of 86

1.

Beclin1-induced autophagy abrogates radioresistance of lung cancer cells by suppressing osteopontin.

Chang SH, Minai-Tehrani A, Shin JY, Park S, Kim JE, Yu KN, Hong SH, Hong CM, Lee KH, Beck GR Jr, Cho MH.

J Radiat Res. 2012;53(3):422-32. Epub 2012 Apr 6.

2.

Hypoxia-induced autophagy contributes to radioresistance via c-Jun-mediated Beclin1 expression in lung cancer cells.

Zou YM, Hu GY, Zhao XQ, Lu T, Zhu F, Yu SY, Xiong H.

J Huazhong Univ Sci Technolog Med Sci. 2014 Oct;34(5):761-7. doi: 10.1007/s11596-014-1349-2. Epub 2014 Oct 16.

PMID:
25318890
3.

Knockdown of autophagy-related gene BECLIN1 promotes cell growth and inhibits apoptosis in the A549 human lung cancer cell line.

Wang W, Fan H, Zhou Y, Duan P, Zhao G, Wu G.

Mol Med Rep. 2013 May;7(5):1501-5. doi: 10.3892/mmr.2013.1379. Epub 2013 Mar 19.

PMID:
23525201
4.

Beclin 1 and UVRAG confer protection from radiation-induced DNA damage and maintain centrosome stability in colorectal cancer cells.

Park JM, Tougeron D, Huang S, Okamoto K, Sinicrope FA.

PLoS One. 2014 Jun 23;9(6):e100819. doi: 10.1371/journal.pone.0100819. eCollection 2014.

5.

Osteopontin knockdown inhibits αv,β3 integrin-induced cell migration and invasion and promotes apoptosis of breast cancer cells by inducing autophagy and inactivating the PI3K/Akt/mTOR pathway.

Zhang H, Guo M, Chen JH, Wang Z, Du XF, Liu PX, Li WH.

Cell Physiol Biochem. 2014;33(4):991-1002. doi: 10.1159/000358670. Epub 2014 Apr 1.

6.

The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells.

Lomonaco SL, Finniss S, Xiang C, Decarvalho A, Umansky F, Kalkanis SN, Mikkelsen T, Brodie C.

Int J Cancer. 2009 Aug 1;125(3):717-22. doi: 10.1002/ijc.24402.

7.

Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation.

Pang XL, He G, Liu YB, Wang Y, Zhang B.

World J Gastroenterol. 2013 Mar 21;19(11):1736-48. doi: 10.3748/wjg.v19.i11.1736.

8.

Overexpression of beclin1 induced autophagy and apoptosis in lungs of K-rasLA1 mice.

Shin JY, Hong SH, Kang B, Minai-Tehrani A, Cho MH.

Lung Cancer. 2013 Sep;81(3):362-70. doi: 10.1016/j.lungcan.2013.05.009. Epub 2013 Jun 18.

PMID:
23790316
9.

MicroRNA-216a enhances the radiosensitivity of pancreatic cancer cells by inhibiting beclin-1-mediated autophagy.

Zhang X, Shi H, Lin S, Ba M, Cui S.

Oncol Rep. 2015 Sep;34(3):1557-64. doi: 10.3892/or.2015.4078. Epub 2015 Jun 25.

PMID:
26134156
10.

Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling.

Ko A, Kanehisa A, Martins I, Senovilla L, Chargari C, Dugue D, Mariño G, Kepp O, Michaud M, Perfettini JL, Kroemer G, Deutsch E.

Cell Death Differ. 2014 Jan;21(1):92-9. doi: 10.1038/cdd.2013.124. Epub 2013 Sep 13.

11.

DNA-dependent protein kinase catalytic subunit inhibitor reverses acquired radioresistance in lung adenocarcinoma by suppressing DNA repair.

Li Y, Li H, Peng W, He XY, Huang M, Qiu D, Xue YB, Lu L.

Mol Med Rep. 2015 Jul;12(1):1328-34. doi: 10.3892/mmr.2015.3505. Epub 2015 Mar 18.

PMID:
25815686
12.

Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer.

Li YY, Lam SK, Mak JC, Zheng CY, Ho JC.

Lung Cancer. 2013 Sep;81(3):354-61. doi: 10.1016/j.lungcan.2013.05.012. Epub 2013 Jun 13.

PMID:
23769318
13.

Cardiac glycosides induce autophagy in human non-small cell lung cancer cells through regulation of dual signaling pathways.

Wang Y, Qiu Q, Shen JJ, Li DD, Jiang XJ, Si SY, Shao RG, Wang Z.

Int J Biochem Cell Biol. 2012 Nov;44(11):1813-24. doi: 10.1016/j.biocel.2012.06.028. Epub 2012 Jun 27.

PMID:
22750415
14.

Lentiviral-mediated siRNA targeted against osteopontin suppresses the growth and metastasis of gastric cancer cells.

Wang ZM, Cui YH, Li W, Chen SY, Liu TS.

Oncol Rep. 2011 Apr;25(4):997-1003. doi: 10.3892/or.2011.1168. Epub 2011 Jan 31.

PMID:
21286666
15.

Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer.

Zinn RL, Gardner EE, Dobromilskaya I, Murphy S, Marchionni L, Hann CL, Rudin CM.

Mol Cancer. 2013 Mar 2;12:16. doi: 10.1186/1476-4598-12-16.

16.

miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1.

Korkmaz G, le Sage C, Tekirdag KA, Agami R, Gozuacik D.

Autophagy. 2012 Feb 1;8(2):165-76. doi: 10.4161/auto.8.2.18351. Epub 2012 Feb 1.

PMID:
22248718
17.

Beclin1 inhibits proliferation, migration and invasion in tongue squamous cell carcinoma cell lines.

Weng J, Wang C, Wang Y, Tang H, Liang J, Liu X, Huang H, Hou J.

Oral Oncol. 2014 Oct;50(10):983-90. doi: 10.1016/j.oraloncology.2014.06.020. Epub 2014 Aug 2.

PMID:
25096824
18.

The tumor suppressor, p53, contributes to radiosensitivity of lung cancer cells by regulating autophagy and apoptosis.

Cheng G, Kong D, Hou X, Liang B, He M, Liang N, Ma S, Liu X.

Cancer Biother Radiopharm. 2013 Mar;28(2):153-9. doi: 10.1089/cbr.2012.1297. Epub 2012 Dec 26.

19.

MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy.

Zou Z, Wu L, Ding H, Wang Y, Zhang Y, Chen X, Chen X, Zhang CY, Zhang Q, Zen K.

J Biol Chem. 2012 Feb 3;287(6):4148-56. doi: 10.1074/jbc.M111.307405. Epub 2011 Dec 8.

20.

Differential roles of miR-199a-5p in radiation-induced autophagy in breast cancer cells.

Yi H, Liang B, Jia J, Liang N, Xu H, Ju G, Ma S, Liu X.

FEBS Lett. 2013 Mar 1;587(5):436-43. doi: 10.1016/j.febslet.2012.12.027. Epub 2013 Jan 18.

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