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Items: 1 to 20 of 172

1.

Ultrastructural analysis of IpaD at the tip of the nascent MxiH type III secretion apparatus of Shigella flexneri.

Epler CR, Dickenson NE, Bullitt E, Picking WL.

J Mol Biol. 2012 Jun 29;420(1-2):29-39. doi: 10.1016/j.jmb.2012.03.025. Epub 2012 Apr 2.

2.

N-terminus of IpaB provides a potential anchor to the Shigella type III secretion system tip complex protein IpaD.

Dickenson NE, Arizmendi O, Patil MK, Toth RT 4th, Middaugh CR, Picking WD, Picking WL.

Biochemistry. 2013 Dec 10;52(49):8790-9. doi: 10.1021/bi400755f. Epub 2013 Nov 20.

3.

Identification of the MxiH needle protein residues responsible for anchoring invasion plasmid antigen D to the type III secretion needle tip.

Zhang L, Wang Y, Olive AJ, Smith ND, Picking WD, De Guzman RN, Picking WL.

J Biol Chem. 2007 Nov 2;282(44):32144-51. Epub 2007 Sep 7.

4.

Conformational changes in IpaD from Shigella flexneri upon binding bile salts provide insight into the second step of type III secretion.

Dickenson NE, Zhang L, Epler CR, Adam PR, Picking WL, Picking WD.

Biochemistry. 2011 Jan 18;50(2):172-80. Epub 2010 Dec 15.

5.

IpaD localizes to the tip of the type III secretion system needle of Shigella flexneri.

Espina M, Olive AJ, Kenjale R, Moore DS, Ausar SF, Kaminski RW, Oaks EV, Middaugh CR, Picking WD, Picking WL.

Infect Immun. 2006 Aug;74(8):4391-400.

6.

Deoxycholate interacts with IpaD of Shigella flexneri in inducing the recruitment of IpaB to the type III secretion apparatus needle tip.

Stensrud KF, Adam PR, La Mar CD, Olive AJ, Lushington GH, Sudharsan R, Shelton NL, Givens RS, Picking WL, Picking WD.

J Biol Chem. 2008 Jul 4;283(27):18646-54. doi: 10.1074/jbc.M802799200. Epub 2008 May 1.

7.

IpaD is localized at the tip of the Shigella flexneri type III secretion apparatus.

Sani M, Botteaux A, Parsot C, Sansonetti P, Boekema EJ, Allaoui A.

Biochim Biophys Acta. 2007 Feb;1770(2):307-11. Epub 2006 Oct 18.

PMID:
17110044
8.

Bile salts stimulate recruitment of IpaB to the Shigella flexneri surface, where it colocalizes with IpaD at the tip of the type III secretion needle.

Olive AJ, Kenjale R, Espina M, Moore DS, Picking WL, Picking WD.

Infect Immun. 2007 May;75(5):2626-9. Epub 2007 Feb 12.

9.

Identification of the bile salt binding site on IpaD from Shigella flexneri and the influence of ligand binding on IpaD structure.

Barta ML, Guragain M, Adam P, Dickenson NE, Patil M, Geisbrecht BV, Picking WL, Picking WD.

Proteins. 2012 Mar;80(3):935-45.

10.

Binding affects the tertiary and quaternary structures of the Shigella translocator protein IpaB and its chaperone IpgC.

Adam PR, Patil MK, Dickenson NE, Choudhari S, Barta M, Geisbrecht BV, Picking WL, Picking WD.

Biochemistry. 2012 May 15;51(19):4062-71. doi: 10.1021/bi300243z. Epub 2012 May 1.

11.

Single-domain antibodies pinpoint potential targets within Shigella invasion plasmid antigen D of the needle tip complex for inhibition of type III secretion.

Barta ML, Shearer JP, Arizmendi O, Tremblay JM, Mehzabeen N, Zheng Q, Battaile KP, Lovell S, Tzipori S, Picking WD, Shoemaker CB, Picking WL.

J Biol Chem. 2017 Oct 6;292(40):16677-16687. doi: 10.1074/jbc.M117.802231. Epub 2017 Aug 25.

PMID:
28842484
12.
13.

Functional insights into the Shigella type III needle tip IpaD in secretion control and cell contact.

Schiavolin L, Meghraoui A, Cherradi Y, Biskri L, Botteaux A, Allaoui A.

Mol Microbiol. 2013 Apr;88(2):268-82. doi: 10.1111/mmi.12185. Epub 2013 Mar 11.

14.

Liposomes recruit IpaC to the Shigella flexneri type III secretion apparatus needle as a final step in secretion induction.

Epler CR, Dickenson NE, Olive AJ, Picking WL, Picking WD.

Infect Immun. 2009 Jul;77(7):2754-61. doi: 10.1128/IAI.00190-09. Epub 2009 May 11.

15.

Oligomeric states of the Shigella translocator protein IpaB provide structural insights into formation of the type III secretion translocon.

Dickenson NE, Choudhari SP, Adam PR, Kramer RM, Joshi SB, Middaugh CR, Picking WL, Picking WD.

Protein Sci. 2013 May;22(5):614-27. doi: 10.1002/pro.2245. Epub 2013 Mar 18.

16.

Domains of the Shigella flexneri type III secretion system IpaB protein involved in secretion regulation.

Shen DK, Saurya S, Wagner C, Nishioka H, Blocker AJ.

Infect Immun. 2010 Dec;78(12):4999-5010. doi: 10.1128/IAI.00470-10. Epub 2010 Oct 11.

17.

IpaD of Shigella flexneri is independently required for regulation of Ipa protein secretion and efficient insertion of IpaB and IpaC into host membranes.

Picking WL, Nishioka H, Hearn PD, Baxter MA, Harrington AT, Blocker A, Picking WD.

Infect Immun. 2005 Mar;73(3):1432-40.

18.

The needle component of the type III secreton of Shigella regulates the activity of the secretion apparatus.

Kenjale R, Wilson J, Zenk SF, Saurya S, Picking WL, Picking WD, Blocker A.

J Biol Chem. 2005 Dec 30;280(52):42929-37. Epub 2005 Oct 14.

19.

Three-dimensional electron microscopy reconstruction and cysteine-mediated crosslinking provide a model of the type III secretion system needle tip complex.

Cheung M, Shen DK, Makino F, Kato T, Roehrich AD, Martinez-Argudo I, Walker ML, Murillo I, Liu X, Pain M, Brown J, Frazer G, Mantell J, Mina P, Todd T, Sessions RB, Namba K, Blocker AJ.

Mol Microbiol. 2015 Jan;95(1):31-50. doi: 10.1111/mmi.12843. Epub 2014 Nov 27.

20.

Shigella IpaD has a dual role: signal transduction from the type III secretion system needle tip and intracellular secretion regulation.

Roehrich AD, Guillossou E, Blocker AJ, Martinez-Argudo I.

Mol Microbiol. 2013 Feb;87(3):690-706. doi: 10.1111/mmi.12124. Epub 2013 Jan 11.

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