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Items: 1 to 20 of 73

1.

Increased promoter methylation of the immune regulatory gene SHP-1 in leukocytes of multiple sclerosis subjects.

Kumagai C, Kalman B, Middleton FA, Vyshkina T, Massa PT.

J Neuroimmunol. 2012 May 15;246(1-2):51-7. doi: 10.1016/j.jneuroim.2012.03.003. Epub 2012 Mar 27.

2.

Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype.

Christophi GP, Panos M, Hudson CA, Christophi RL, Gruber RC, Mersich AT, Blystone SD, Jubelt B, Massa PT.

Lab Invest. 2009 Jul;89(7):742-59. doi: 10.1038/labinvest.2009.32. Epub 2009 Apr 27.

3.

Mechanisms of SHP-1 P2 promoter regulation in hematopoietic cells and its silencing in HTLV-1-transformed T cells.

Nakase K, Cheng J, Zhu Q, Marasco WA.

J Leukoc Biol. 2009 Jan;85(1):165-74. doi: 10.1189/jlb.0608383. Epub 2008 Nov 12.

4.

Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.

Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT.

Clin Immunol. 2009 Oct;133(1):27-44. doi: 10.1016/j.clim.2009.05.019. Epub 2009 Jun 25.

5.

The SHP-1 expression is associated with cytokines and psychopathological status in unmedicated first episode schizophrenia patients.

Pesce M, Ferrone A, Rizzuto A, Tatangelo R, Iezzi I, Ladu S, Franceschelli S, Speranza L, Patruno A, Felaco M, Grilli A.

Brain Behav Immun. 2014 Oct;41:251-60. doi: 10.1016/j.bbi.2014.04.008. Epub 2014 Apr 30.

PMID:
24793756
6.

SHP-1 deficiency and increased inflammatory gene expression in PBMCs of multiple sclerosis patients.

Christophi GP, Hudson CA, Gruber RC, Christophi CP, Mihai C, Mejico LJ, Jubelt B, Massa PT.

Lab Invest. 2008 Mar;88(3):243-55. doi: 10.1038/labinvest.3700720. Epub 2008 Jan 21.

7.

Methylation and decreased expression of SHP-1 are related to disease progression in chronic myelogenous leukemia.

Li Y, Yang L, Pan Y, Yang J, Shang Y, Luo J.

Oncol Rep. 2014 May;31(5):2438-46. doi: 10.3892/or.2014.3098. Epub 2014 Mar 19.

PMID:
24647617
8.

Negative regulation of the SH2-homology containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoprotein.

Cheng J, Kydd AR, Nakase K, Noonan KM, Murakami A, Tao H, Dwyer M, Xu C, Zhu Q, Marasco WA.

Blood. 2007 Sep 15;110(6):2110-20. Epub 2007 May 31.

9.

The control of reactive oxygen species production by SHP-1 in oligodendrocytes.

Gruber RC, LaRocca D, Minchenberg SB, Christophi GP, Hudson CA, Ray AK, Shafit-Zagardo B, Massa PT.

Glia. 2015 Oct;63(10):1753-71. doi: 10.1002/glia.22842. Epub 2015 Apr 27.

10.

[As2O3 induces demethylation and up-regulates transcription of SHP-1 gene in human lymphoma cell line T2 cells].

Yang L, Luo JM, Li Y, Liu XJ, Wen SP, Du XY, Yao L, Yang JC, Dong ZR.

Zhonghua Zhong Liu Za Zhi. 2009 Jun;31(6):423-7. Chinese.

PMID:
19950550
11.

[Experimental study of SHP-1 promoter methylation in myelodysplastic syndromes and its related mechanism].

Zhang YZ, Zhao DD, Zhao WP, Zhao HF, Zhao ZG, Wang YF, Wu XX, Han XP, Da WM.

Zhonghua Xue Ye Xue Za Zhi. 2012 Feb;33(2):108-12. Chinese.

PMID:
22730659
12.

Cell surface expression of channel catfish leukocyte immune-type receptors (IpLITRs) and recruitment of both Src homology 2 domain-containing protein tyrosine phosphatase (SHP)-1 and SHP-2.

Montgomery BC, Mewes J, Davidson C, Burshtyn DN, Stafford JL.

Dev Comp Immunol. 2009 Apr;33(4):570-82. doi: 10.1016/j.dci.2008.10.006. Epub 2008 Nov 12.

PMID:
19013191
13.

Constitutive activation of STAT3 in Sézary syndrome is independent of SHP-1.

McKenzie RC, Jones CL, Tosi I, Caesar JA, Whittaker SJ, Mitchell TJ.

Leukemia. 2012 Feb;26(2):323-31. doi: 10.1038/leu.2011.198. Epub 2011 Aug 5.

PMID:
21818116
14.

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.

Zhang Q, Wang HY, Marzec M, Raghunath PN, Nagasawa T, Wasik MA.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6948-53. Epub 2005 May 3.

15.

Hypermethylation of SHP-1 promoter in patient with high-risk myelodysplastic syndrome and it predicts poor prognosis.

Zhang Y, Zhao D, Zhao H, Wu X, Zhao W, Wang Y, Xia B, Da W.

Med Oncol. 2012 Dec;29(4):2359-63. doi: 10.1007/s12032-012-0163-6. Epub 2012 Jan 19.

PMID:
22258937
16.

[Effect of a methylation inhibitor 5-aza-2'-deoxycytidine on SHP-1 gene expression, proliferation and apoptosis in K562 cells].

Luo JM, Li Y, Yang L, Liu XJ, Wen SP, Wang FX, Zhang JY, Zhang XJ, Dong ZR.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Apr;17(2):309-14. Chinese.

PMID:
19379557
17.

SHP-1 promoter 2 methylation in normal epithelial tissues and demethylation in psoriasis.

Ruchusatsawat K, Wongpiyabovorn J, Shuangshoti S, Hirankarn N, Mutirangura A.

J Mol Med (Berl). 2006 Feb;84(2):175-82. Epub 2005 Dec 31.

PMID:
16389548
18.

Identification of a novel lipid raft-targeting motif in Src homology 2-containing phosphatase 1.

Sankarshanan M, Ma Z, Iype T, Lorenz U.

J Immunol. 2007 Jul 1;179(1):483-90.

19.

The gene encoding hematopoietic cell phosphatase (SHP-1) is structurally and transcriptionally intact in polycythemia vera.

Asimakopoulos FA, Hinshelwood S, Gilbert JG, Delibrias CC, Göttgens B, Fearon DT, Green AR.

Oncogene. 1997 Mar 13;14(10):1215-22.

20.

Association between methylation of SHP-1 isoform I and SSTR2A promoter regions with breast and prostate carcinoma development.

Tiscornia MM, González HS, Lorenzati MA, Zapata PD.

Cancer Invest. 2015 Mar;33(3):61-9. doi: 10.3109/07357907.2014.1001892. Epub 2015 Jan 30.

PMID:
25635370

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