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Items: 1 to 20 of 137

1.

Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia.

Rubio MD, Haroutunian V, Meador-Woodruff JH.

Biol Psychiatry. 2012 May 15;71(10):906-14. doi: 10.1016/j.biopsych.2012.02.006. Epub 2012 Mar 27.

2.
3.

Altered expression of CDC42 signaling pathway components in cortical layer 3 pyramidal cells in schizophrenia.

Datta D, Arion D, Corradi JP, Lewis DA.

Biol Psychiatry. 2015 Dec 1;78(11):775-85. doi: 10.1016/j.biopsych.2015.03.030. Epub 2015 Apr 11.

4.

A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC.

Zhang H, Webb DJ, Asmussen H, Niu S, Horwitz AF.

J Neurosci. 2005 Mar 30;25(13):3379-88.

5.

PAK1 protein expression in the auditory cortex of schizophrenia subjects.

Deo AJ, Goldszer IM, Li S, DiBitetto JV, Henteleff R, Sampson A, Lewis DA, Penzes P, Sweet RA.

PLoS One. 2013 Apr 22;8(4):e59458. doi: 10.1371/journal.pone.0059458. Print 2013.

6.

Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophrenia.

Funk AJ, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH.

Neuropsychopharmacology. 2012 Mar;37(4):896-905. doi: 10.1038/npp.2011.267. Epub 2011 Nov 2.

7.

Inhibition of myosin light chain kinase by p21-activated kinase.

Sanders LC, Matsumura F, Bokoch GM, de Lanerolle P.

Science. 1999 Mar 26;283(5410):2083-5.

8.

Altered cortical CDC42 signaling pathways in schizophrenia: implications for dendritic spine deficits.

Ide M, Lewis DA.

Biol Psychiatry. 2010 Jul 1;68(1):25-32. doi: 10.1016/j.biopsych.2010.02.016. Epub 2010 Apr 10.

9.

Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1.

Parrini MC, Lei M, Harrison SC, Mayer BJ.

Mol Cell. 2002 Jan;9(1):73-83.

10.

Pak1 regulates branching morphogenesis in 3D MDCK cell culture by a PIX and beta1-integrin-dependent mechanism.

Hunter MP, Zegers MM.

Am J Physiol Cell Physiol. 2010 Jul;299(1):C21-32. doi: 10.1152/ajpcell.00543.2009. Epub 2010 Mar 24.

11.

The rho guanosine 5'-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell.

Lim GE, Xu M, Sun J, Jin T, Brubaker PL.

Endocrinology. 2009 Dec;150(12):5249-61. doi: 10.1210/en.2009-0508. Epub 2009 Oct 9.

PMID:
19819966
13.
15.

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics.

Edwards DC, Sanders LC, Bokoch GM, Gill GN.

Nat Cell Biol. 1999 Sep;1(5):253-9.

PMID:
10559936
16.

Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells.

Parsons M, Monypenny J, Ameer-Beg SM, Millard TH, Machesky LM, Peter M, Keppler MD, Schiavo G, Watson R, Chernoff J, Zicha D, Vojnovic B, Ng T.

Mol Cell Biol. 2005 Mar;25(5):1680-95.

17.

Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia.

Kristiansen LV, Beneyto M, Haroutunian V, Meador-Woodruff JH.

Mol Psychiatry. 2006 Aug;11(8):737-47, 705. Epub 2006 May 16.

PMID:
16702973
18.
19.

Inhibition of contraction and myosin light chain phosphorylation in guinea-pig smooth muscle by p21-activated kinase 1.

Wirth A, Schroeter M, Kock-Hauser C, Manser E, Chalovich JM, De Lanerolle P, Pfitzer G.

J Physiol. 2003 Jun 1;549(Pt 2):489-500. Epub 2003 Apr 11.

20.

Biphasic regulation of myosin light chain phosphorylation by p21-activated kinase modulates intestinal smooth muscle contractility.

Chu J, Pham NT, Olate N, Kislitsyna K, Day MC, LeTourneau PA, Kots A, Stewart RH, Laine GA, Cox CS Jr, Uray K.

J Biol Chem. 2013 Jan 11;288(2):1200-13. doi: 10.1074/jbc.M112.370718. Epub 2012 Nov 16.

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