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Items: 1 to 20 of 217


Adult obesity susceptibility variants are associated with greater childhood weight gain and a faster tempo of growth: the 1946 British Birth Cohort Study.

Elks CE, Loos RJ, Hardy R, Wills AK, Wong A, Wareham NJ, Kuh D, Ong KK.

Am J Clin Nutr. 2012 May;95(5):1150-6. doi: 10.3945/ajcn.111.027870. Epub 2012 Mar 28.


Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.

Elks CE, Loos RJ, Sharp SJ, Langenberg C, Ring SM, Timpson NJ, Ness AR, Davey Smith G, Dunger DB, Wareham NJ, Ong KK.

PLoS Med. 2010 May 25;7(5):e1000284. doi: 10.1371/journal.pmed.1000284.


Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals.

Kilpeläinen TO, den Hoed M, Ong KK, Grøntved A, Brage S; Early Growth Genetics Consortium, Jameson K, Cooper C, Khaw KT, Ekelund U, Wareham NJ, Loos RJ.

Am J Clin Nutr. 2011 Apr;93(4):851-60. doi: 10.3945/ajcn.110.000828. Epub 2011 Jan 19.


Life course variations in the associations between FTO and MC4R gene variants and body size.

Hardy R, Wills AK, Wong A, Elks CE, Wareham NJ, Loos RJ, Kuh D, Ong KK.

Hum Mol Genet. 2010 Feb 1;19(3):545-52. doi: 10.1093/hmg/ddp504. Epub 2009 Oct 31.


Modelling BMI trajectories in children for genetic association studies.

Warrington NM, Wu YY, Pennell CE, Marsh JA, Beilin LJ, Palmer LJ, Lye SJ, Briollais L.

PLoS One. 2013;8(1):e53897. doi: 10.1371/journal.pone.0053897. Epub 2013 Jan 17.


Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.

Ng MC, Tam CH, So WY, Ho JS, Chan AW, Lee HM, Wang Y, Lam VK, Chan JC, Ma RC.

J Clin Endocrinol Metab. 2010 May;95(5):2418-25. doi: 10.1210/jc.2009-2077. Epub 2010 Mar 9.


Associations between genetic obesity susceptibility and early postnatal fat and lean mass: an individual participant meta-analysis.

Elks CE, Heude B, de Zegher F, Barton SJ, Clément K, Inskip HM, Koudou Y, Cooper C, Dunger DB, Ibáñez L, Charles MA, Ong KK.

JAMA Pediatr. 2014 Dec;168(12):1122-30. doi: 10.1001/jamapediatrics.2014.1619.


Genetic susceptibility, birth weight and obesity risk in young Chinese.

Hong J, Shi J, Qi L, Cui B, Gu W, Zhang Y, Li L, Xu M, Wang L, Zhai Y, Miao L, Wang R, Bi Y, Wang W, Ning G.

Int J Obes (Lond). 2013 May;37(5):673-7. doi: 10.1038/ijo.2012.87. Epub 2012 Jun 19.


Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies.

den Hoed M, Ekelund U, Brage S, Grontved A, Zhao JH, Sharp SJ, Ong KK, Wareham NJ, Loos RJ.

Diabetes. 2010 Nov;59(11):2980-8. doi: 10.2337/db10-0370. Epub 2010 Aug 19.


Influence of the beta2-adrenergic receptor Arg16Gly polymorphism on longitudinal changes in obesity from childhood through young adulthood in a biracial cohort: the Bogalusa Heart Study.

Ellsworth DL, Coady SA, Chen W, Srinivasan SR, Elkasabany A, Gustat J, Boerwinkle E, Berenson GS.

Int J Obes Relat Metab Disord. 2002 Jul;26(7):928-37.


Polygenic Risk, Appetite Traits, and Weight Gain in Middle Childhood: A Longitudinal Study.

Steinsbekk S, Belsky D, Guzey IC, Wardle J, Wichstrøm L.

JAMA Pediatr. 2016 Feb;170(2):e154472. doi: 10.1001/jamapediatrics.2015.4472. Epub 2016 Feb 1.


No impact of obesity susceptibility loci on weight regain after a lifestyle intervention in overweight children.

Hinney A, Wolters B, Pütter C, Grallert H, Illig T, Hebebrand J, Reinehr T.

J Pediatr Endocrinol Metab. 2013;26(11-12):1209-13. doi: 10.1515/jpem-2013-0179.


Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.

Li S, Zhao JH, Luan J, Luben RN, Rodwell SA, Khaw KT, Ong KK, Wareham NJ, Loos RJ.

Am J Clin Nutr. 2010 Jan;91(1):184-90. doi: 10.3945/ajcn.2009.28403. Epub 2009 Oct 7.


Associations between the pubertal timing-related variant in LIN28B and BMI vary across the life course.

Ong KK, Elks CE, Wills AK, Wong A, Wareham NJ, Loos RJ, Kuh D, Hardy R.

J Clin Endocrinol Metab. 2011 Jan;96(1):E125-9. doi: 10.1210/jc.2010-0941. Epub 2010 Oct 20.


Longitudinal replication studies of GWAS risk SNPs influencing body mass index over the course of childhood and adulthood.

Mei H, Chen W, Jiang F, He J, Srinivasan S, Smith EN, Schork N, Murray S, Berenson GS.

PLoS One. 2012;7(2):e31470. doi: 10.1371/journal.pone.0031470. Epub 2012 Feb 15.


Obesity-susceptibility loci and the tails of the pediatric BMI distribution.

Mitchell JA, Hakonarson H, Rebbeck TR, Grant SF.

Obesity (Silver Spring). 2013 Jun;21(6):1256-60. doi: 10.1002/oby.20319.


Inverse relationship between a genetic risk score of 31 BMI loci and weight change before and after reaching middle age.

Rukh G, Ahmad S, Ericson U, Hindy G, Stocks T, Renström F, Almgren P, Nilsson PM, Melander O, Franks PW, Orho-Melander M.

Int J Obes (Lond). 2016 Feb;40(2):252-9. doi: 10.1038/ijo.2015.180. Epub 2015 Sep 16.


Progressive influence of body mass index-associated genetic markers in rural Gambians.

Fulford AJ, Ong KK, Elks CE, Prentice AM, Hennig BJ.

J Med Genet. 2015 Jun;52(6):375-80. doi: 10.1136/jmedgenet-2014-102784. Epub 2015 Apr 28.


Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study.

Jess T, Zimmermann E, Kring SI, Berentzen T, Holst C, Toubro S, Astrup A, Hansen T, Pedersen O, Sørensen TI.

Int J Obes (Lond). 2008 Sep;32(9):1388-94. doi: 10.1038/ijo.2008.110. Epub 2008 Jul 29.


Mendelian Randomisation Study of Childhood BMI and Early Menarche.

Mumby HS, Elks CE, Li S, Sharp SJ, Khaw KT, Luben RN, Wareham NJ, Loos RJ, Ong KK.

J Obes. 2011;2011:180729. doi: 10.1155/2011/180729. Epub 2011 May 18.

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