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Items: 1 to 20 of 227

1.

Polycystin-1 and polycystin-2 are both required to amplify inositol-trisphosphate-induced Ca2+ release.

Mekahli D, Sammels E, Luyten T, Welkenhuyzen K, van den Heuvel LP, Levtchenko EN, Gijsbers R, Bultynck G, Parys JB, De Smedt H, Missiaen L.

Cell Calcium. 2012 Jun;51(6):452-8. doi: 10.1016/j.ceca.2012.03.002. Epub 2012 Mar 27.

PMID:
22456092
2.

Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.

Sammels E, Devogelaere B, Mekahli D, Bultynck G, Missiaen L, Parys JB, Cai Y, Somlo S, De Smedt H.

J Biol Chem. 2010 Jun 11;285(24):18794-805. doi: 10.1074/jbc.M109.090662. Epub 2010 Apr 7.

3.

Unraveling the role of polycystin-2/inositol 1,4,5-trisphosphate receptor interaction in Ca signaling.

Sammels E, Devogelaere B, Mekahli D, Bultynck G, Missiaen L, Parys JB, De Smedt H.

Commun Integr Biol. 2010 Nov;3(6):530-2. doi: 10.4161/cib.3.6.12751. Epub 2010 Nov 1.

4.

Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease.

Li Y, Santoso NG, Yu S, Woodward OM, Qian F, Guggino WB.

J Biol Chem. 2009 Dec 25;284(52):36431-41. doi: 10.1074/jbc.M109.068916. Epub 2009 Oct 23.

5.

Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling.

Li Y, Wright JM, Qian F, Germino GG, Guggino WB.

J Biol Chem. 2005 Dec 16;280(50):41298-306. Epub 2005 Oct 13.

7.
8.

Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease.

Vassilev PM, Guo L, Chen XZ, Segal Y, Peng JB, Basora N, Babakhanlou H, Cruger G, Kanazirska M, Ye Cp, Brown EM, Hediger MA, Zhou J.

Biochem Biophys Res Commun. 2001 Mar 23;282(1):341-50.

PMID:
11264013
9.

Polycystins: what polycystic kidney disease tells us about sperm.

Kierszenbaum AL.

Mol Reprod Dev. 2004 Apr;67(4):385-8. Review.

PMID:
14991728
10.

Autosomal dominant polycystic kidney disease: clues to pathogenesis.

Harris PC.

Hum Mol Genet. 1999;8(10):1861-6. Review.

PMID:
10469838
11.

Secretory granules in inositol 1,4,5-trisphosphate-dependent Ca2+ signaling in the cytoplasm of neuroendocrine cells.

Yoo SH.

FASEB J. 2010 Mar;24(3):653-64. doi: 10.1096/fj.09-132456. Epub 2009 Oct 16. Review.

12.

Cyst formation following disruption of intracellular calcium signaling.

Kuo IY, DesRochers TM, Kimmerling EP, Nguyen L, Ehrlich BE, Kaplan DL.

Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14283-8. doi: 10.1073/pnas.1412323111. Epub 2014 Sep 16.

13.

Fertilization and inositol 1,4,5-trisphosphate (IP3)-induced calcium release in type-1 inositol 1,4,5-trisphosphate receptor down-regulated bovine eggs.

Malcuit C, Knott JG, He C, Wainwright T, Parys JB, Robl JM, Fissore RA.

Biol Reprod. 2005 Jul;73(1):2-13. Epub 2005 Mar 2.

PMID:
15744020
14.

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents.

Hanaoka K, Qian F, Boletta A, Bhunia AK, Piontek K, Tsiokas L, Sukhatme VP, Guggino WB, Germino GG.

Nature. 2000 Dec 21-28;408(6815):990-4.

PMID:
11140688
15.

Current advances in molecular genetics of autosomal-dominant polycystic kidney disease.

Wu G.

Curr Opin Nephrol Hypertens. 2001 Jan;10(1):23-31. Review.

PMID:
11195048
16.
17.

Molecular basis of autosomal dominant polycystic kidney disease.

Al-Bhalal L, Akhtar M.

Adv Anat Pathol. 2005 May;12(3):126-33. Review.

PMID:
15900113
18.

Heterologous expression of polycystin-1 inhibits endoplasmic reticulum calcium leak in stably transfected MDCK cells.

Weber KH, Lee EK, Basavanna U, Lindley S, Ziegelstein RC, Germino GG, Sutters M.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1279-86. doi: 10.1152/ajprenal.00348.2007. Epub 2008 Apr 16.

19.

Inhibition of mitochondrial calcium uptake rather than efflux impedes calcium release by inositol-1,4,5-trisphosphate-sensitive receptors.

Chalmers S, McCarron JG.

Cell Calcium. 2009 Aug;46(2):107-13. doi: 10.1016/j.ceca.2009.05.007. Epub 2009 Jul 4.

PMID:
19577805
20.

Polycystin-1, 2, and STIM1 interact with IP(3)R to modulate ER Ca release through the PI3K/Akt pathway.

Santoso NG, Cebotaru L, Guggino WB.

Cell Physiol Biochem. 2011;27(6):715-26. doi: 10.1159/000330080. Epub 2011 Jun 17.

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