Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 138

1.

Mutations in Streptococcus pneumoniae penicillin-binding protein 2x: importance of the C-terminal penicillin-binding protein and serine/threonine kinase-associated domains for beta-lactam binding.

Maurer P, Todorova K, Sauerbier J, Hakenbeck R.

Microb Drug Resist. 2012 Jun;18(3):314-21. doi: 10.1089/mdr.2012.0022. Epub 2012 Mar 28.

PMID:
22455550
2.

Penicillin-binding protein 2x of Streptococcus pneumoniae: three new mutational pathways for remodelling an essential enzyme into a resistance determinant.

Maurer P, Koch B, Zerfass I, Krauss J, van der Linden M, Frère JM, Contreras-Martel C, Hakenbeck R.

J Mol Biol. 2008 Mar 7;376(5):1403-16. doi: 10.1016/j.jmb.2007.12.058. Epub 2008 Jan 4.

PMID:
18234221
3.

Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics.

Mouz N, Di Guilmi AM, Gordon E, Hakenbeck R, Dideberg O, Vernet T.

J Biol Chem. 1999 Jul 2;274(27):19175-80.

4.

An important site in PBP2x of penicillin-resistant clinical isolates of Streptococcus pneumoniae: mutational analysis of Thr338.

Zerfass I, Hakenbeck R, Denapaite D.

Antimicrob Agents Chemother. 2009 Mar;53(3):1107-15. doi: 10.1128/AAC.01107-08. Epub 2008 Dec 15.

5.
6.
7.

Molecular dynamics simulation of the complex PBP-2x with drug cefuroxime to explore the drug resistance mechanism of Streptococcus suis R61.

Ge Y, Wu J, Xia Y, Yang M, Xiao J, Yu J.

PLoS One. 2012;7(4):e35941. doi: 10.1371/journal.pone.0035941. Epub 2012 Apr 26.

8.

Penicillin-binding protein 2x of Streptococcus pneumoniae: the mutation Ala707Asp within the C-terminal PASTA2 domain leads to destabilization.

Schweizer I, Peters K, Stahlmann C, Hakenbeck R, Denapaite D.

Microb Drug Resist. 2014 Jun;20(3):250-7. doi: 10.1089/mdr.2014.0082. Epub 2014 May 19.

9.
11.

Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae.

Contreras-Martel C, Job V, Di Guilmi AM, Vernet T, Dideberg O, Dessen A.

J Mol Biol. 2006 Jan 27;355(4):684-96. Epub 2005 Nov 9.

PMID:
16316661
13.

Highly variable penicillin resistance determinants PBP 2x, PBP 2b, and PBP 1a in isolates of two Streptococcus pneumoniae clonal groups, Poland 23F-16 and Poland 6B-20.

Izdebski R, Rutschmann J, Fiett J, Sadowy E, Gniadkowski M, Hryniewicz W, Hakenbeck R.

Antimicrob Agents Chemother. 2008 Mar;52(3):1021-7. Epub 2007 Dec 26.

14.

Computational studies on the resistance of penicillin-binding protein 2B (PBP2B) of wild-type and mutant strains of Streptococcus pneumoniae against β-lactam antibiotics.

Ramalingam J, Vennila J, Subbiah P.

Chem Biol Drug Des. 2013 Sep;82(3):275-89. doi: 10.1111/j.1747-0285.2012.01387.x. Epub 2013 Jul 25.

PMID:
22448818
16.

Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations.

Dessen A, Mouz N, Gordon E, Hopkins J, Dideberg O.

J Biol Chem. 2001 Nov 30;276(48):45106-12. Epub 2001 Sep 11.

17.

Streptococcus pneumoniae PBP2x mid-cell localization requires the C-terminal PASTA domains and is essential for cell shape maintenance.

Peters K, Schweizer I, Beilharz K, Stahlmann C, Veening JW, Hakenbeck R, Denapaite D.

Mol Microbiol. 2014 May;92(4):733-55. doi: 10.1111/mmi.12588. Epub 2014 Apr 17.

20.

[Evaluation of penicillin-binding protein genotypes in penicillin susceptible and resistant Streptococcus pneumoniae isolates].

Aslan G, Tezcan S, Delialioğlu N, Aydın FE, Kuyucu N, Emekdaş G.

Mikrobiyol Bul. 2012 Apr;46(2):190-201. Turkish.

PMID:
22639308

Supplemental Content

Support Center