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Items: 1 to 20 of 108

1.

Shaping the role of mitochondria in the pathogenesis of Huntington's disease.

Costa V, Scorrano L.

EMBO J. 2012 Apr 18;31(8):1853-64. doi: 10.1038/emboj.2012.65. Epub 2012 Mar 23. Review.

2.

hMTH1 expression protects mitochondria from Huntington's disease-like impairment.

Ventura I, Russo MT, De Nuccio C, De Luca G, Degan P, Bernardo A, Visentin S, Minghetti L, Bignami M.

Neurobiol Dis. 2013 Jan;49:148-58. doi: 10.1016/j.nbd.2012.09.002. Epub 2012 Sep 10.

3.

Mitochondrial functional alterations in relation to pathophysiology of Huntington's disease.

Pandey M, Mohanakumar KP, Usha R.

J Bioenerg Biomembr. 2010 Jun;42(3):217-26. doi: 10.1007/s10863-010-9288-5. Review.

PMID:
20464463
4.

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.

Shirendeb U, Reddy AP, Manczak M, Calkins MJ, Mao P, Tagle DA, Reddy PH.

Hum Mol Genet. 2011 Apr 1;20(7):1438-55. doi: 10.1093/hmg/ddr024. Epub 2011 Jan 21.

5.

Mitochondrial bioenergetics and dynamics in Huntington's disease: tripartite synapses and selective striatal degeneration.

Oliveira JM.

J Bioenerg Biomembr. 2010 Jun;42(3):227-34. doi: 10.1007/s10863-010-9287-6. Review.

PMID:
20454921
6.

The mGluR5 positive allosteric modulator, CDPPB, ameliorates pathology and phenotypic signs of a mouse model of Huntington's disease.

Doria JG, de Souza JM, Andrade JN, Rodrigues HA, Guimaraes IM, Carvalho TG, Guatimosim C, Dobransky T, Ribeiro FM.

Neurobiol Dis. 2015 Jan;73:163-73. doi: 10.1016/j.nbd.2014.08.021. Epub 2014 Aug 24.

PMID:
25160573
7.

Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease.

Quintanilla RA, Johnson GV.

Brain Res Bull. 2009 Oct 28;80(4-5):242-7. doi: 10.1016/j.brainresbull.2009.07.010. Epub 2009 Jul 19. Review.

8.

A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin.

Damiano M, Diguet E, Malgorn C, D'Aurelio M, Galvan L, Petit F, Benhaim L, Guillermier M, Houitte D, Dufour N, Hantraye P, Canals JM, Alberch J, Delzescaux T, Déglon N, Beal MF, Brouillet E.

Hum Mol Genet. 2013 Oct 1;22(19):3869-82. doi: 10.1093/hmg/ddt242. Epub 2013 May 29.

9.

Mitochondrial matters of the brain: the role in Huntington's disease.

Turner C, Schapira AH.

J Bioenerg Biomembr. 2010 Jun;42(3):193-8. doi: 10.1007/s10863-010-9290-y. Review.

PMID:
20480217
10.

Mitochondrial structural and functional dynamics in Huntington's disease.

Reddy PH, Mao P, Manczak M.

Brain Res Rev. 2009 Jun;61(1):33-48. doi: 10.1016/j.brainresrev.2009.04.001. Epub 2009 Apr 24. Review.

11.

Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli.

Costa V, Giacomello M, Hudec R, Lopreiato R, Ermak G, Lim D, Malorni W, Davies KJ, Carafoli E, Scorrano L.

EMBO Mol Med. 2010 Dec;2(12):490-503. doi: 10.1002/emmm.201000102.

12.

[The role of mitochondria in the pathogenesis of Huntington's disease].

Karachitos A, Gałgańska H, Kmita H.

Postepy Biochem. 2010;56(2):174-81. Review. Polish.

PMID:
20873112
13.

Nature and cause of mitochondrial dysfunction in Huntington's disease: focusing on huntingtin and the striatum.

Oliveira JM.

J Neurochem. 2010 Jul;114(1):1-12. doi: 10.1111/j.1471-4159.2010.06741.x. Epub 2010 Apr 9. Review.

14.

Effects of overexpression of huntingtin proteins on mitochondrial integrity.

Wang H, Lim PJ, Karbowski M, Monteiro MJ.

Hum Mol Genet. 2009 Feb 15;18(4):737-52. doi: 10.1093/hmg/ddn404. Epub 2008 Nov 27.

15.

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

Panov AV, Gutekunst CA, Leavitt BR, Hayden MR, Burke JR, Strittmatter WJ, Greenamyre JT.

Nat Neurosci. 2002 Aug;5(8):731-6.

PMID:
12089530
16.

Dysregulation of synaptic proteins, dendritic spine abnormalities and pathological plasticity of synapses as experience-dependent mediators of cognitive and psychiatric symptoms in Huntington's disease.

Nithianantharajah J, Hannan AJ.

Neuroscience. 2013 Oct 22;251:66-74. doi: 10.1016/j.neuroscience.2012.05.043. Epub 2012 May 24. Review.

PMID:
22633949
17.

N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.

Orr AL, Li S, Wang CE, Li H, Wang J, Rong J, Xu X, Mastroberardino PG, Greenamyre JT, Li XJ.

J Neurosci. 2008 Mar 12;28(11):2783-92. doi: 10.1523/JNEUROSCI.0106-08.2008.

18.

Mitochondria and Huntington's disease pathogenesis: insight from genetic and chemical models.

Browne SE.

Ann N Y Acad Sci. 2008 Dec;1147:358-82. doi: 10.1196/annals.1427.018. Review.

PMID:
19076457
19.

Towards a transgenic model of Huntington's disease in a non-human primate.

Yang SH, Cheng PH, Banta H, Piotrowska-Nitsche K, Yang JJ, Cheng EC, Snyder B, Larkin K, Liu J, Orkin J, Fang ZH, Smith Y, Bachevalier J, Zola SM, Li SH, Li XJ, Chan AW.

Nature. 2008 Jun 12;453(7197):921-4. doi: 10.1038/nature06975. Epub 2008 May 18.

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