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The Ets-1 transcription factor is required for Stat1-mediated T-bet expression and IgG2a class switching in mouse B cells.

Nguyen HV, Mouly E, Chemin K, Luinaud R, Despres R, Fermand JP, Arnulf B, Bories JC.

Blood. 2012 May 3;119(18):4174-81. doi: 10.1182/blood-2011-09-378182.


Induction of IgG2a class switching in B cells by IL-27.

Yoshimoto T, Okada K, Morishima N, Kamiya S, Owaki T, Asakawa M, Iwakura Y, Fukai F, Mizuguchi J.

J Immunol. 2004 Aug 15;173(4):2479-85.


T-bet regulates T-independent IgG2a class switching.

Gerth AJ, Lin L, Peng SL.

Int Immunol. 2003 Aug;15(8):937-44.


CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells.

Liu N, Ohnishi N, Ni L, Akira S, Bacon KB.

Nat Immunol. 2003 Jul;4(7):687-93.


T-bet regulates IgG class switching and pathogenic autoantibody production.

Peng SL, Szabo SJ, Glimcher LH.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5545-50.


Regulation of IFN-gamma production by B effector 1 cells: essential roles for T-bet and the IFN-gamma receptor.

Harris DP, Goodrich S, Gerth AJ, Peng SL, Lund FE.

J Immunol. 2005 Jun 1;174(11):6781-90.


T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells.

Afkarian M, Sedy JR, Yang J, Jacobson NG, Cereb N, Yang SY, Murphy TL, Murphy KM.

Nat Immunol. 2002 Jun;3(6):549-57.


T-bet-independent effects of IL-12 family cytokines on regulation of Th17 responses to experimental T. cruzi infection.

Cobb D, Hambright D, Smeltz RB.

J Leukoc Biol. 2010 Nov;88(5):965-71. doi: 10.1189/jlb.0410238.


B cells genetically deficient in the c-Rel transactivation domain have selective defects in germline CH transcription and Ig class switching.

Zelazowski P, Carrasco D, Rosas FR, Moorman MA, Bravo R, Snapper CM.

J Immunol. 1997 Oct 1;159(7):3133-9.


STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination.

Linehan LA, Warren WD, Thompson PA, Grusby MJ, Berton MT.

J Immunol. 1998 Jul 1;161(1):302-10.


Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production.

Tsukamoto Y, Nagai Y, Kariyone A, Shibata T, Kaisho T, Akira S, Miyake K, Takatsu K.

Mol Immunol. 2009 Apr;46(7):1278-88. doi: 10.1016/j.molimm.2008.11.022.


Essential role of Stat5 for IL-5-dependent IgH switch recombination in mouse B cells.

Horikawa K, Kaku H, Nakajima H, Davey HW, Hennighausen L, Iwamoto I, Yasue T, Kariyone A, Takatsu K.

J Immunol. 2001 Nov 1;167(9):5018-26.


IFN-gamma-dependent and -independent initiation of switch recombination by NK cells.

Gao N, Dang T, Yuan D.

J Immunol. 2001 Aug 15;167(4):2011-8.


STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and -independent mechanisms.

Villarino AV, Gallo E, Abbas AK.

J Immunol. 2010 Dec 1;185(11):6461-71. doi: 10.4049/jimmunol.1001343.


Cutting edge: T-bet and IL-27R are critical for in vivo IFN-gamma production by CD8 T cells during infection.

Mayer KD, Mohrs K, Reiley W, Wittmer S, Kohlmeier JE, Pearl JE, Cooper AM, Johnson LL, Woodland DL, Mohrs M.

J Immunol. 2008 Jan 15;180(2):693-7.


Requirements for the natural killer cell-mediated induction of IgG1 and IgG2a expression in B lymphocytes.

Gao N, Jennings P, Yuan D.

Int Immunol. 2008 May;20(5):645-57. doi: 10.1093/intimm/dxn021.


Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα.

Wang NS, McHeyzer-Williams LJ, Okitsu SL, Burris TP, Reiner SL, McHeyzer-Williams MG.

Nat Immunol. 2012 May 6;13(6):604-11. doi: 10.1038/ni.2294.

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