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Items: 1 to 20 of 77

1.

Structural approaches to probing metal interaction with proteins.

Parker LJ, Ascher DB, Gao C, Miles LA, Harris HH, Parker MW.

J Inorg Biochem. 2012 Oct;115:138-47. doi: 10.1016/j.jinorgbio.2012.02.015. Epub 2012 Mar 3. Review.

PMID:
22437159
2.

Copper brain homeostasis: role of amyloid precursor protein and prion protein.

Inestrosa NC, Cerpa W, Varela-Nallar L.

IUBMB Life. 2005 Sep;57(9):645-50. Review.

3.

Structure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolution.

Kong GK, Adams JJ, Cappai R, Parker MW.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Oct 1;63(Pt 10):819-24. Epub 2007 Sep 19.

4.

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis.

Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS, Beyreuther K, Masters CL, Parker MW, Cappai R.

J Biol Chem. 2003 May 9;278(19):17401-7. Epub 2003 Feb 28.

5.

Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide.

Donnelly PS, Caragounis A, Du T, Laughton KM, Volitakis I, Cherny RA, Sharples RA, Hill AF, Li QX, Masters CL, Barnham KJ, White AR.

J Biol Chem. 2008 Feb 22;283(8):4568-77. Epub 2007 Dec 17.

6.

Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade.

Taru H, Iijima K, Hase M, Kirino Y, Yagi Y, Suzuki T.

J Biol Chem. 2002 May 31;277(22):20070-8. Epub 2002 Mar 22.

7.

Aluminum, copper, iron and zinc differentially alter amyloid-Aβ(1-42) aggregation and toxicity.

Bolognin S, Messori L, Drago D, Gabbiani C, Cendron L, Zatta P.

Int J Biochem Cell Biol. 2011 Jun;43(6):877-85. doi: 10.1016/j.biocel.2011.02.009. Epub 2011 Mar 3.

PMID:
21376832
8.

Metal chelation as a potential therapy for Alzheimer's disease.

Cuajungco MP, Fagét KY, Huang X, Tanzi RE, Bush AI.

Ann N Y Acad Sci. 2000;920:292-304. Review.

PMID:
11193167
9.

Copper(I) and copper(II) inhibit Aβ peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease.

Grasso G, Pietropaolo A, Spoto G, Pappalardo G, Tundo GR, Ciaccio C, Coletta M, Rizzarelli E.

Chemistry. 2011 Feb 25;17(9):2752-62. doi: 10.1002/chem.201002809. Epub 2011 Jan 27.

PMID:
21274957
10.

Copper and oxidative stress in the pathogenesis of Alzheimer's disease.

Eskici G, Axelsen PH.

Biochemistry. 2012 Aug 14;51(32):6289-311. Epub 2012 Jul 31. Review.

PMID:
22708607
11.

Redox silencing of copper in metal-linked neurodegenerative disorders: reaction of Zn7metallothionein-3 with Cu2+ ions.

Meloni G, Faller P, Vasák M.

J Biol Chem. 2007 Jun 1;282(22):16068-78. Epub 2007 Mar 27.

12.

Zinc takes the center stage: its paradoxical role in Alzheimer's disease.

Cuajungco MP, Fagét KY.

Brain Res Brain Res Rev. 2003 Jan;41(1):44-56. Review.

PMID:
12505647
13.

Binding of zinc(II) and copper(II) to the full-length Alzheimer's amyloid-beta peptide.

Tõugu V, Karafin A, Palumaa P.

J Neurochem. 2008 Mar;104(5):1249-59. doi: 10.1111/j.1471-4159.2007.05061.x.

14.

Proteolytic processing of the amyloid-beta protein precursor of Alzheimer's disease.

Nunan J, Small DH.

Essays Biochem. 2002;38:37-49. Review.

PMID:
12463160
15.

Metal binding dictates conformation and function of the amyloid precursor protein (APP) E2 domain.

Dahms SO, Könnig I, Roeser D, Gührs KH, Mayer MC, Kaden D, Multhaup G, Than ME.

J Mol Biol. 2012 Feb 24;416(3):438-52. doi: 10.1016/j.jmb.2011.12.057. Epub 2012 Jan 4.

16.

The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

Multhaup G, Schlicksupp A, Hesse L, Beher D, Ruppert T, Masters CL, Beyreuther K.

Science. 1996 Mar 8;271(5254):1406-9.

PMID:
8596911
17.

Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene.

Bellingham SA, Lahiri DK, Maloney B, La Fontaine S, Multhaup G, Camakaris J.

J Biol Chem. 2004 May 7;279(19):20378-86. Epub 2004 Feb 25.

18.

Interactions of Zn(II) and Cu(II) ions with Alzheimer's amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity.

Tõugu V, Tiiman A, Palumaa P.

Metallomics. 2011 Mar;3(3):250-61. doi: 10.1039/c0mt00073f. Epub 2011 Feb 25. Review.

PMID:
21359283
19.

Zinc-mediated modulation of the configuration and activity of complexes between copper and amyloid-β peptides.

Liu L, Xia N.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):153-6. doi: 10.1016/j.bbrc.2011.11.074. Epub 2011 Nov 23. Retraction in: Biochem Biophys Res Commun. 2012 Aug 17;425(1):120.

PMID:
22138653
20.

Metals and Alzheimer's disease.

Adlard PA, Bush AI.

J Alzheimers Dis. 2006 Nov;10(2-3):145-63. Review.

PMID:
17119284

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