Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 107


Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components.

Kanke M, Kodama Y, Takahashi TS, Nakagawa T, Masukata H.

EMBO J. 2012 May 2;31(9):2182-94. doi: 10.1038/emboj.2012.68. Epub 2012 Mar 20.


Mcm10 plays a role in functioning of the eukaryotic replicative DNA helicase, Cdc45-Mcm-GINS.

Watase G, Takisawa H, Kanemaki MT.

Curr Biol. 2012 Feb 21;22(4):343-9. doi: 10.1016/j.cub.2012.01.023. Epub 2012 Jan 26.


Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation.

van Deursen F, Sengupta S, De Piccoli G, Sanchez-Diaz A, Labib K.

EMBO J. 2012 May 2;31(9):2195-206. doi: 10.1038/emboj.2012.69. Epub 2012 Mar 20.


Mcm10 coordinates the timely assembly and activation of the replication fork helicase.

Perez-Arnaiz P, Bruck I, Kaplan DL.

Nucleic Acids Res. 2016 Jan 8;44(1):315-29. doi: 10.1093/nar/gkv1260. Epub 2015 Nov 17.


DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast.

Handa T, Kanke M, Takahashi TS, Nakagawa T, Masukata H.

Mol Biol Cell. 2012 Aug;23(16):3240-53. doi: 10.1091/mbc.E12-05-0339. Epub 2012 Jun 20.


Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase.

Lõoke M, Maloney MF, Bell SP.

Genes Dev. 2017 Feb 1;31(3):291-305. doi: 10.1101/gad.291336.116.


Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins.

Im JS, Ki SH, Farina A, Jung DS, Hurwitz J, Lee JK.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15628-32. doi: 10.1073/pnas.0908039106. Epub 2009 Sep 8.


Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability.

Araki Y, Kawasaki Y, Sasanuma H, Tye BK, Sugino A.

Genes Cells. 2003 May;8(5):465-80.


Origin single-stranded DNA releases Sld3 protein from the Mcm2-7 complex, allowing the GINS tetramer to bind the Mcm2-7 complex.

Bruck I, Kaplan DL.

J Biol Chem. 2011 May 27;286(21):18602-13. doi: 10.1074/jbc.M111.226332. Epub 2011 Apr 1.


Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha.

Ricke RM, Bielinsky AK.

Mol Cell. 2004 Oct 22;16(2):173-85.


Recruitment of Mcm10 to Sites of Replication Initiation Requires Direct Binding to the Minichromosome Maintenance (MCM) Complex.

Douglas ME, Diffley JF.

J Biol Chem. 2016 Mar 11;291(11):5879-88. doi: 10.1074/jbc.M115.707802. Epub 2015 Dec 30.


GINS and Sld3 compete with one another for Mcm2-7 and Cdc45 binding.

Bruck I, Kaplan DL.

J Biol Chem. 2011 Apr 22;286(16):14157-67. doi: 10.1074/jbc.M111.218305. Epub 2011 Mar 1.


The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication.

Van Hatten RA, Tutter AV, Holway AH, Khederian AM, Walter JC, Michael WM.

J Cell Biol. 2002 Nov 25;159(4):541-7. Epub 2002 Nov 18.


Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.

Homesley L, Lei M, Kawasaki Y, Sawyer S, Christensen T, Tye BK.

Genes Dev. 2000 Apr 15;14(8):913-26.


Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding.

Gregan J, Lindner K, Brimage L, Franklin R, Namdar M, Hart EA, Aves SJ, Kearsey SE.

Mol Biol Cell. 2003 Sep;14(9):3876-87. Epub 2003 Jun 13.


Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks.

Baxley RM, Bielinsky AK.

Genes (Basel). 2017 Feb 17;8(2). pii: E73. doi: 10.3390/genes8020073. Review.


The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

Costa A, Ilves I, Tamberg N, Petojevic T, Nogales E, Botchan MR, Berger JM.

Nat Struct Mol Biol. 2011 Apr;18(4):471-7. doi: 10.1038/nsmb.2004. Epub 2011 Mar 6.


Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae.

Sawyer SL, Cheng IH, Chai W, Tye BK.

J Mol Biol. 2004 Jul 2;340(2):195-202.


Supplemental Content

Support Center