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Items: 1 to 20 of 118

1.

Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells.

Györy I, Boller S, Nechanitzky R, Mandel E, Pott S, Liu E, Grosschedl R.

Genes Dev. 2012 Apr 1;26(7):668-82. doi: 10.1101/gad.187328.112. Epub 2012 Mar 19.

2.

Essential role of EBF1 in the generation and function of distinct mature B cell types.

Vilagos B, Hoffmann M, Souabni A, Sun Q, Werner B, Medvedovic J, Bilic I, Minnich M, Axelsson E, Jaritz M, Busslinger M.

J Exp Med. 2012 Apr 9;209(4):775-92. doi: 10.1084/jem.20112422. Epub 2012 Apr 2.

3.

Runx1-Cbfβ facilitates early B lymphocyte development by regulating expression of Ebf1.

Seo W, Ikawa T, Kawamoto H, Taniuchi I.

J Exp Med. 2012 Jul 2;209(7):1255-62. doi: 10.1084/jem.20112745. Epub 2012 Jun 4.

4.

Ebf1 and c-Myb repress rag transcription downstream of Stat5 during early B cell development.

Timblin GA, Schlissel MS.

J Immunol. 2013 Nov 1;191(9):4676-87. doi: 10.4049/jimmunol.1301675. Epub 2013 Sep 25.

5.

Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin.

Treiber T, Mandel EM, Pott S, Györy I, Firner S, Liu ET, Grosschedl R.

Immunity. 2010 May 28;32(5):714-25. doi: 10.1016/j.immuni.2010.04.013. Epub 2010 May 6.

6.

STAT5 activation underlies IL7 receptor-dependent B cell development.

Goetz CA, Harmon IR, O'Neil JJ, Burchill MA, Farrar MA.

J Immunol. 2004 Apr 15;172(8):4770-8.

7.

The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation.

Beer-Hammer S, Zebedin E, von Holleben M, Alferink J, Reis B, Dresing P, Degrandi D, Scheu S, Hirsch E, Sexl V, Pfeffer K, Nürnberg B, Piekorz RP.

J Leukoc Biol. 2010 Jun;87(6):1083-95. doi: 10.1189/jlb.0809585. Epub 2010 Mar 3.

PMID:
20200404
8.

The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function.

Boller S, Grosschedl R.

Immunol Rev. 2014 Sep;261(1):102-15. doi: 10.1111/imr.12206. Review.

10.

Enforced expression of the transcriptional coactivator OBF1 impairs B cell differentiation at the earliest stage of development.

Bordon A, Bosco N, Du Roure C, Bartholdy B, Kohler H, Matthias G, Rolink AG, Matthias P.

PLoS One. 2008;3(12):e4007. doi: 10.1371/journal.pone.0004007. Epub 2008 Dec 23.

11.

IRF-2 regulates B-cell proliferation and antibody production through distinct mechanisms.

Minamino K, Takahara K, Adachi T, Nagaoka K, Iyoda T, Taki S, Inaba K.

Int Immunol. 2012 Sep;24(9):573-81. doi: 10.1093/intimm/dxs060. Epub 2012 Jul 5.

PMID:
22773153
12.

Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells.

Nechanitzky R, Akbas D, Scherer S, Györy I, Hoyler T, Ramamoorthy S, Diefenbach A, Grosschedl R.

Nat Immunol. 2013 Aug;14(8):867-75. doi: 10.1038/ni.2641. Epub 2013 Jun 30.

PMID:
23812095
13.

EBF1 acts as a powerful repressor of Blimp-1 gene expression in immature B cells.

Kikuchi H, Nakayama M, Takami Y, Kuribayashi F, Nakayama T.

Biochem Biophys Res Commun. 2012 Jun 15;422(4):780-5. doi: 10.1016/j.bbrc.2012.05.099. Epub 2012 May 24.

PMID:
22634309
14.

Runx1 is essential at two stages of early murine B-cell development.

Niebuhr B, Kriebitzsch N, Fischer M, Behrens K, Günther T, Alawi M, Bergholz U, Müller U, Roscher S, Ziegler M, Buchholz F, Grundhoff A, Stocking C.

Blood. 2013 Jul 18;122(3):413-23. doi: 10.1182/blood-2013-01-480244. Epub 2013 May 23.

15.

Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement.

Kersseboom R, Ta VB, Zijlstra AJ, Middendorp S, Jumaa H, van Loo PF, Hendriks RW.

J Immunol. 2006 Apr 15;176(8):4543-52.

16.

Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression.

Lukin K, Fields S, Lopez D, Cherrier M, Ternyak K, Ramírez J, Feeney AJ, Hagman J.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7869-74. doi: 10.1073/pnas.1003525107. Epub 2010 Apr 12.

17.

The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF.

Tardivel A, Tinel A, Lens S, Steiner QG, Sauberli E, Wilson A, Mackay F, Rolink AG, Beermann F, Tschopp J, Schneider P.

Eur J Immunol. 2004 Feb;34(2):509-18.

18.

A dose-dependent role for EBF1 in repressing non-B-cell-specific genes.

Lukin K, Fields S, Guerrettaz L, Straign D, Rodriguez V, Zandi S, Månsson R, Cambier JC, Sigvardsson M, Hagman J.

Eur J Immunol. 2011 Jun;41(6):1787-93. doi: 10.1002/eji.201041137. Epub 2011 May 9.

19.

Transcriptional repression of Gata3 is essential for early B cell commitment.

Banerjee A, Northrup D, Boukarabila H, Jacobsen SE, Allman D.

Immunity. 2013 May 23;38(5):930-42. doi: 10.1016/j.immuni.2013.01.014. Epub 2013 May 16.

20.

EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors.

Zandi S, Mansson R, Tsapogas P, Zetterblad J, Bryder D, Sigvardsson M.

J Immunol. 2008 Sep 1;181(5):3364-72.

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