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Items: 1 to 20 of 81

1.

Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance.

Zhang Y, Li Y, Niepel MW, Kawano Y, Han S, Liu S, Marsili A, Larsen PR, Lee CH, Cohen DE.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5417-22. doi: 10.1073/pnas.1116011109. Epub 2012 Mar 16.

2.

Thioesterase superfamily member 1 suppresses cold thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids in brown adipose tissue.

Okada K, LeClair KB, Zhang Y, Li Y, Ozdemir C, Krisko TI, Hagen SJ, Betensky RA, Banks AS, Cohen DE.

Mol Metab. 2016 Feb 23;5(5):340-51. doi: 10.1016/j.molmet.2016.02.002. eCollection 2016 May.

3.

Functional characterization of thioesterase superfamily member 1/Acyl-CoA thioesterase 11: implications for metabolic regulation.

Han S, Cohen DE.

J Lipid Res. 2012 Dec;53(12):2620-31. doi: 10.1194/jlr.M029538. Epub 2012 Sep 19.

4.

Regulation of Fatty Acid Trafficking in Liver by Thioesterase Superfamily Member 1.

Desai A, Alves-Bezerra M, Li Y, Ozdemir C, Bare CJ, Li Y, Hagen SJ, Cohen DE.

J Lipid Res. 2017 Dec 5. pii: jlr.M081455. doi: 10.1194/jlr.M081455. [Epub ahead of print]

5.

Thioesterase superfamily member 2/Acyl-CoA thioesterase 13 (Them2/Acot13) regulates adaptive thermogenesis in mice.

Kang HW, Ozdemir C, Kawano Y, LeClair KB, Vernochet C, Kahn CR, Hagen SJ, Cohen DE.

J Biol Chem. 2013 Nov 15;288(46):33376-86. doi: 10.1074/jbc.M113.481408. Epub 2013 Sep 26.

6.
7.

Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice.

Huang J, Jia Y, Fu T, Viswakarma N, Bai L, Rao MS, Zhu Y, Borensztajn J, Reddy JK.

FASEB J. 2012 Feb;26(2):628-38. doi: 10.1096/fj.11-194019. Epub 2011 Oct 18.

8.
9.

Thioesterase superfamily member 2/acyl-CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism.

Kang HW, Niepel MW, Han S, Kawano Y, Cohen DE.

FASEB J. 2012 May;26(5):2209-21. doi: 10.1096/fj.11-202853. Epub 2012 Feb 17.

10.

BFIT, a unique acyl-CoA thioesterase induced in thermogenic brown adipose tissue: cloning, organization of the human gene and assessment of a potential link to obesity.

Adams SH, Chui C, Schilbach SL, Yu XX, Goddard AD, Grimaldi JC, Lee J, Dowd P, Colman S, Lewin DA.

Biochem J. 2001 Nov 15;360(Pt 1):135-42.

11.

Metabolic and tissue-specific regulation of acyl-CoA metabolism.

Ellis JM, Bowman CE, Wolfgang MJ.

PLoS One. 2015 Mar 11;10(3):e0116587. doi: 10.1371/journal.pone.0116587. eCollection 2015.

12.

The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes.

Westin MA, Hunt MC, Alexson SE.

J Biol Chem. 2005 Nov 18;280(46):38125-32. Epub 2005 Aug 31.

13.

Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation.

Orellana-Gavaldà JM, Herrero L, Malandrino MI, Pañeda A, Sol Rodríguez-Peña M, Petry H, Asins G, Van Deventer S, Hegardt FG, Serra D.

Hepatology. 2011 Mar;53(3):821-32. doi: 10.1002/hep.24140. Epub 2011 Feb 11.

PMID:
21319201
14.

Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation.

Li JZ, Ye J, Xue B, Qi J, Zhang J, Zhou Z, Li Q, Wen Z, Li P.

Diabetes. 2007 Oct;56(10):2523-32. Epub 2007 Jul 23.

15.

Acyl coenzyme A thioesterase 7 regulates neuronal fatty acid metabolism to prevent neurotoxicity.

Ellis JM, Wong GW, Wolfgang MJ.

Mol Cell Biol. 2013 May;33(9):1869-82. doi: 10.1128/MCB.01548-12. Epub 2013 Mar 4.

16.

Distinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulin.

Durgan DJ, Smith JK, Hotze MA, Egbejimi O, Cuthbert KD, Zaha VG, Dyck JR, Abel ED, Young ME.

Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2480-97. Epub 2006 Jan 20.

PMID:
16428347
17.

Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.

Hunt MC, Nousiainen SE, Huttunen MK, Orii KE, Svensson LT, Alexson SE.

J Biol Chem. 1999 Nov 26;274(48):34317-26.

18.

Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet.

Bjursell M, Admyre T, Göransson M, Marley AE, Smith DM, Oscarsson J, Bohlooly-Y M.

Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E211-20. doi: 10.1152/ajpendo.00229.2010. Epub 2010 Oct 19.

PMID:
20959533
19.

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.

PMID:
23928105
20.

Thioesterase superfamily member 2 (Them2) and phosphatidylcholine transfer protein (PC-TP) interact to promote fatty acid oxidation and control glucose utilization.

Kawano Y, Ersoy BA, Li Y, Nishiumi S, Yoshida M, Cohen DE.

Mol Cell Biol. 2014 Jul;34(13):2396-408. doi: 10.1128/MCB.01601-13. Epub 2014 Apr 14.

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