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Cofactors required for TLR7- and TLR9-dependent innate immune responses.

Chiang CY, Engel A, Opaluch AM, Ramos I, Maestre AM, Secundino I, De Jesus PD, Nguyen QT, Welch G, Bonamy GM, Miraglia LJ, Orth AP, Nizet V, Fernandez-Sesma A, Zhou Y, Barton GM, Chanda SK.

Cell Host Microbe. 2012 Mar 15;11(3):306-18. doi: 10.1016/j.chom.2012.02.002.


Regulatory molecules required for nucleotide-sensing Toll-like receptors.

Saitoh S, Miyake K.

Immunol Rev. 2009 Jan;227(1):32-43. doi: 10.1111/j.1600-065X.2008.00729.x. Review.


HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection.

Luo Z, Ge M, Chen J, Geng Q, Tian M, Qiao Z, Bai L, Zhang Q, Zhu C, Xiong Y, Wu K, Liu F, Liu Y, Wu J.

PLoS Pathog. 2017 Aug 30;13(8):e1006585. doi: 10.1371/journal.ppat.1006585. eCollection 2017 Aug.


Toll-like receptor 7 mediates early innate immune responses to malaria.

Baccarella A, Fontana MF, Chen EC, Kim CC.

Infect Immun. 2013 Dec;81(12):4431-42. doi: 10.1128/IAI.00923-13. Epub 2013 Sep 16.


Contribution of TLR7 and TLR9 signaling to the susceptibility of MyD88-deficient mice to myocarditis.

Pagni PP, Traub S, Demaria O, Chasson L, Alexopoulou L.

Autoimmunity. 2010 Jun;43(4):275-87. doi: 10.3109/08916930903509056.


Activation of NF-κB via endosomal Toll-like receptor 7 (TLR7) or TLR9 suppresses murine herpesvirus 68 reactivation.

Haas F, Yamauchi K, Murat M, Bernasconi M, Yamanaka N, Speck RF, Nadal D.

J Virol. 2014 Sep 1;88(17):10002-12. doi: 10.1128/JVI.01486-14. Epub 2014 Jun 18.


Bruton's tyrosine kinase regulates TLR9 but not TLR7 signaling in human plasmacytoid dendritic cells.

Wang J, Lau KY, Jung J, Ravindran P, Barrat FJ.

Eur J Immunol. 2014 Apr;44(4):1130-6. doi: 10.1002/eji.201344030. Epub 2014 Jan 20.


[Multilevel maturation of Toll-like receptor 9].

Zyzak J, Matuszyk J, Siednienko J.

Postepy Hig Med Dosw (Online). 2013 Oct 30;67:1034-46. Review. Polish.


The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

Ewald SE, Lee BL, Lau L, Wickliffe KE, Shi GP, Chapman HA, Barton GM.

Nature. 2008 Dec 4;456(7222):658-62. doi: 10.1038/nature07405. Epub 2008 Sep 28.


Toll-like receptor and RIG-I-like receptor signaling.

Kawai T, Akira S.

Ann N Y Acad Sci. 2008 Nov;1143:1-20. doi: 10.1196/annals.1443.020. Review.


Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9.

Guiducci C, Tripodo C, Gong M, Sangaletti S, Colombo MP, Coffman RL, Barrat FJ.

J Exp Med. 2010 Dec 20;207(13):2931-42. doi: 10.1084/jem.20101048. Epub 2010 Nov 29.


Antigen-specific T-cell responses to a recombinant fowlpox virus are dependent on MyD88 and interleukin-18 and independent of Toll-like receptor 7 (TLR7)- and TLR9-mediated innate immune recognition.

Lousberg EL, Diener KR, Fraser CK, Phipps S, Foster PS, Chen W, Uematsu S, Akira S, Robertson SA, Brown MP, Hayball JD.

J Virol. 2011 Apr;85(7):3385-96. doi: 10.1128/JVI.02000-10. Epub 2011 Jan 19.


Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses.

Kimura T, Endo S, Inui M, Saitoh S, Miyake K, Takai T.

J Immunol. 2015 Jun 1;194(11):5426-36. doi: 10.4049/jimmunol.1402006. Epub 2015 Apr 27.


Endocytic pathway is required for Drosophila Toll innate immune signaling.

Huang HR, Chen ZJ, Kunes S, Chang GD, Maniatis T.

Proc Natl Acad Sci U S A. 2010 May 4;107(18):8322-7. doi: 10.1073/pnas.1004031107. Epub 2010 Apr 19.


The functional effects of physical interactions among Toll-like receptors 7, 8, and 9.

Wang J, Shao Y, Bennett TA, Shankar RA, Wightman PD, Reddy LG.

J Biol Chem. 2006 Dec 8;281(49):37427-34. Epub 2006 Oct 13.


Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9.

Newman ZR, Young JM, Ingolia NT, Barton GM.

Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1362-71. doi: 10.1073/pnas.1518976113. Epub 2016 Feb 22.


BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells.

Combes A, Camosseto V, N'Guessan P, Argüello RJ, Mussard J, Caux C, Bendriss-Vermare N, Pierre P, Gatti E.

Nat Commun. 2017 Oct 13;8(1):913. doi: 10.1038/s41467-017-00695-1.


Cytidine-phosphate-guanosine oligonucleotides induce interleukin-8 production through activation of TLR9, MyD88, NF-κB, and ERK pathways in odontoblast cells.

He W, Zhang Y, Zhang J, Yu Q, Wang P, Wang Z, Smith AJ.

J Endod. 2012 Jun;38(6):780-5. doi: 10.1016/j.joen.2012.02.026. Epub 2012 Apr 4.


Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo.

Appledorn DM, Patial S, McBride A, Godbehere S, Van Rooijen N, Parameswaran N, Amalfitano A.

J Immunol. 2008 Aug 1;181(3):2134-44.

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