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Items: 1 to 20 of 91

1.

The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity.

Yang CS, Rodgers M, Min CK, Lee JS, Kingeter L, Lee JY, Jong A, Kramnik I, Lin X, Jung JU.

Cell Host Microbe. 2012 Mar 15;11(3):277-89. doi: 10.1016/j.chom.2012.01.019.

2.

Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.

Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, Lee KH, Kim CJ, Oh B, Zandi E, Yue Z, Kramnik I, Liang C, Jung JU.

Cell Host Microbe. 2012 Mar 15;11(3):264-76. doi: 10.1016/j.chom.2012.01.018.

3.

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity.

Gross O, Gewies A, Finger K, Schäfer M, Sparwasser T, Peschel C, Förster I, Ruland J.

Nature. 2006 Aug 10;442(7103):651-6. Epub 2006 Jul 12.

PMID:
16862125
4.

C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation.

Zhao XQ, Zhu LL, Chang Q, Jiang C, You Y, Luo T, Jia XM, Lin X.

J Biol Chem. 2014 Oct 24;289(43):30052-62. doi: 10.1074/jbc.M114.588574. Epub 2014 Sep 8.

5.

CARD9 mediates Dectin-1-induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity.

Jia XM, Tang B, Zhu LL, Liu YH, Zhao XQ, Gorjestani S, Hsu YM, Yang L, Guan JH, Xu GT, Lin X.

J Exp Med. 2014 Oct 20;211(11):2307-21. doi: 10.1084/jem.20132349. Epub 2014 Sep 29.

6.

Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity.

Strasser D, Neumann K, Bergmann H, Marakalala MJ, Guler R, Rojowska A, Hopfner KP, Brombacher F, Urlaub H, Baier G, Brown GD, Leitges M, Ruland J.

Immunity. 2012 Jan 27;36(1):32-42. doi: 10.1016/j.immuni.2011.11.015.

7.

AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-κB signaling upon T cell activation.

Schimmack G, Eitelhuber AC, Vincendeau M, Demski K, Shinohara H, Kurosaki T, Krappmann D.

Cell Commun Signal. 2014 Jul 22;12:49. doi: 10.1186/s12964-014-0049-7.

8.

Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-kappaB and MAPK activation to selectively control cytokine production.

Gross O, Grupp C, Steinberg C, Zimmermann S, Strasser D, Hannesschläger N, Reindl W, Jonsson H, Huo H, Littman DR, Peschel C, Yokoyama WM, Krug A, Ruland J.

Blood. 2008 Sep 15;112(6):2421-8. doi: 10.1182/blood-2007-11-123513. Epub 2008 Jan 11.

9.

Rubicon Modulates Antiviral Type I Interferon (IFN) Signaling by Targeting IFN Regulatory Factor 3 Dimerization.

Kim JH, Kim TH, Lee HC, Nikapitiya C, Uddin MB, Park ME, Pathinayake P, Lee ES, Chathuranga K, Herath TUB, Chathuranga WAG, Lee JS.

J Virol. 2017 Jun 26;91(14). pii: e00248-17. doi: 10.1128/JVI.00248-17. Print 2017 Jul 15.

PMID:
28468885
10.

CARD9 mediates dectin-2-induced IkappaBalpha kinase ubiquitination leading to activation of NF-kappaB in response to stimulation by the hyphal form of Candida albicans.

Bi L, Gojestani S, Wu W, Hsu YM, Zhu J, Ariizumi K, Lin X.

J Biol Chem. 2010 Aug 20;285(34):25969-77. doi: 10.1074/jbc.M110.131300. Epub 2010 Jun 9.

11.

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.

Robinson MJ, Osorio F, Rosas M, Freitas RP, Schweighoffer E, Gross O, Verbeek JS, Ruland J, Tybulewicz V, Brown GD, Moita LF, Taylor PR, Reis e Sousa C.

J Exp Med. 2009 Aug 31;206(9):2037-51. doi: 10.1084/jem.20082818. Epub 2009 Aug 24.

12.

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.

LeibundGut-Landmann S, Gross O, Robinson MJ, Osorio F, Slack EC, Tsoni SV, Schweighoffer E, Tybulewicz V, Brown GD, Ruland J, Reis e Sousa C.

Nat Immunol. 2007 Jun;8(6):630-8. Epub 2007 Apr 22.

PMID:
17450144
13.

Genetic errors of the human caspase recruitment domain-B-cell lymphoma 10-mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex: Molecular, immunologic, and clinical heterogeneity.

Pérez de Diego R, Sánchez-Ramón S, López-Collazo E, Martínez-Barricarte R, Cubillos-Zapata C, Ferreira Cerdán A, Casanova JL, Puel A.

J Allergy Clin Immunol. 2015 Nov;136(5):1139-49. doi: 10.1016/j.jaci.2015.06.031. Epub 2015 Aug 12. Review.

14.

The role of Dectin-1 in the host defence against fungal infections.

Drummond RA, Brown GD.

Curr Opin Microbiol. 2011 Aug;14(4):392-9. doi: 10.1016/j.mib.2011.07.001. Epub 2011 Jul 29. Review.

PMID:
21803640
15.

The adaptor CARD9 is required for adaptive but not innate immunity to oral mucosal Candida albicans infections.

Bishu S, Hernández-Santos N, Simpson-Abelson MR, Huppler AR, Conti HR, Ghilardi N, Mamo AJ, Gaffen SL.

Infect Immun. 2014 Mar;82(3):1173-80. doi: 10.1128/IAI.01335-13. Epub 2013 Dec 30.

16.

The Ca2+-dependent phosphatase calcineurin controls the formation of the Carma1-Bcl10-Malt1 complex during T cell receptor-induced NF-kappaB activation.

Palkowitsch L, Marienfeld U, Brunner C, Eitelhuber A, Krappmann D, Marienfeld RB.

J Biol Chem. 2011 Mar 4;286(9):7522-34. doi: 10.1074/jbc.M110.155895. Epub 2011 Jan 3.

17.

Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival.

Bidère N, Ngo VN, Lee J, Collins C, Zheng L, Wan F, Davis RE, Lenz G, Anderson DE, Arnoult D, Vazquez A, Sakai K, Zhang J, Meng Z, Veenstra TD, Staudt LM, Lenardo MJ.

Nature. 2009 Mar 5;458(7234):92-6. doi: 10.1038/nature07613. Epub 2008 Dec 31.

18.

Dectin-1-dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages.

Tam JM, Mansour MK, Khan NS, Seward M, Puranam S, Tanne A, Sokolovska A, Becker CE, Acharya M, Baird MA, Choi AM, Davidson MW, Segal BH, Lacy-Hulbert A, Stuart LM, Xavier RJ, Vyas JM.

J Infect Dis. 2014 Dec 1;210(11):1844-54. doi: 10.1093/infdis/jiu290. Epub 2014 May 19.

19.

Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly.

Qiao Q, Yang C, Zheng C, Fontán L, David L, Yu X, Bracken C, Rosen M, Melnick A, Egelman EH, Wu H.

Mol Cell. 2013 Sep 26;51(6):766-79. doi: 10.1016/j.molcel.2013.08.032.

20.

COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulation.

Welteke V, Eitelhuber A, Düwel M, Schweitzer K, Naumann M, Krappmann D.

EMBO Rep. 2009 Jun;10(6):642-8. doi: 10.1038/embor.2009.64. Epub 2009 May 15.

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