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Items: 1 to 20 of 176


The Rix1 (Ipi1p-2p-3p) complex is a critical determinant of DNA replication licensing independent of their roles in ribosome biogenesis.

Huo L, Wu R, Yu Z, Zhai Y, Yang X, Chan TC, Yeung JT, Kan J, Liang C.

Cell Cycle. 2012 Apr 1;11(7):1325-39. doi: 10.4161/cc.19709.


A Role of hIPI3 in DNA Replication Licensing in Human Cells.

Huang Y, Amin A, Qin Y, Wang Z, Jiang H, Liang L, Shi L, Liang C.

PLoS One. 2016 Apr 8;11(4):e0151803. doi: 10.1371/journal.pone.0151803.


Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast.

Donovan S, Harwood J, Drury LS, Diffley JF.

Proc Natl Acad Sci U S A. 1997 May 27;94(11):5611-6.


Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells.

Kneissl M, Pütter V, Szalay AA, Grummt F.

J Mol Biol. 2003 Mar 14;327(1):111-28.


Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro.

Kawasaki Y, Kim HD, Kojima A, Seki T, Sugino A.

Genes Cells. 2006 Jul;11(7):745-56.


Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase.

Randell JC, Bowers JL, Rodríguez HK, Bell SP.

Mol Cell. 2006 Jan 6;21(1):29-39.


Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.

Remus D, Beuron F, Tolun G, Griffith JD, Morris EP, Diffley JF.

Cell. 2009 Nov 13;139(4):719-30. doi: 10.1016/j.cell.2009.10.015.


Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading.

Chen S, de Vries MA, Bell SP.

Genes Dev. 2007 Nov 15;21(22):2897-907.


Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae.

Ma L, Zhai Y, Feng D, Chan TC, Lu Y, Fu X, Wang J, Chen Y, Li J, Xu K, Liang C.

Cell Cycle. 2010 Nov 1;9(21):4399-410.


The dynamics of eukaryotic replication initiation: origin specificity, licensing, and firing at the single-molecule level.

Duzdevich D, Warner MD, Ticau S, Ivica NA, Bell SP, Greene EC.

Mol Cell. 2015 May 7;58(3):483-94. doi: 10.1016/j.molcel.2015.03.017.


Dynamics of pre-replication complex proteins during the cell division cycle.

Prasanth SG, Méndez J, Prasanth KV, Stillman B.

Philos Trans R Soc Lond B Biol Sci. 2004 Jan 29;359(1441):7-16. Review.


An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexes.

Semple JW, Da-Silva LF, Jervis EJ, Ah-Kee J, Al-Attar H, Kummer L, Heikkila JJ, Pasero P, Duncker BP.

EMBO J. 2006 Nov 1;25(21):5150-8.


The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin.

Weinreich M, Liang C, Stillman B.

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):441-6.


Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly.

Belsky JA, MacAlpine HK, Lubelsky Y, Hartemink AJ, MacAlpine DM.

Genes Dev. 2015 Jan 15;29(2):212-24. doi: 10.1101/gad.247924.114.


Origin licensing requires ATP binding and hydrolysis by the MCM replicative helicase.

Coster G, Frigola J, Beuron F, Morris EP, Diffley JF.

Mol Cell. 2014 Sep 4;55(5):666-77. doi: 10.1016/j.molcel.2014.06.034.

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