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Items: 1 to 20 of 123

1.

Following Ariadne's thread: a new perspective on RBR ubiquitin ligases.

Wenzel DM, Klevit RE.

BMC Biol. 2012 Mar 15;10:24. doi: 10.1186/1741-7007-10-24. Review.

2.

Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.

Lechtenberg BC, Rajput A, Sanishvili R, Dobaczewska MK, Ware CF, Mace PD, Riedl SJ.

Nature. 2016 Jan 28;529(7587):546-50. doi: 10.1038/nature16511. Epub 2016 Jan 20.

3.

Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms.

Dove KK, Stieglitz B, Duncan ED, Rittinger K, Klevit RE.

EMBO Rep. 2016 Aug;17(8):1221-35. doi: 10.15252/embr.201642641. Epub 2016 Jun 16.

4.

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids.

Wenzel DM, Lissounov A, Brzovic PS, Klevit RE.

Nature. 2011 Jun 2;474(7349):105-8. doi: 10.1038/nature09966. Epub 2011 May 1.

5.

RBR E3 ubiquitin ligases: new structures, new insights, new questions.

Spratt DE, Walden H, Shaw GS.

Biochem J. 2014 Mar 15;458(3):421-37. doi: 10.1042/BJ20140006. Review.

6.

RBR E3-ligases at work.

Smit JJ, Sixma TK.

EMBO Rep. 2014 Feb;15(2):142-54. doi: 10.1002/embr.201338166. Epub 2014 Jan 27. Review.

7.

Structure of the HHARI catalytic domain shows glimpses of a HECT E3 ligase.

Spratt DE, Mercier P, Shaw GS.

PLoS One. 2013 Aug 15;8(8):e74047. doi: 10.1371/journal.pone.0074047. eCollection 2013.

8.

RING-, HECT-, and RBR-type E3 Ubiquitin Ligases: Involvement in Human Cancer.

Uchida C, Kitagawa M.

Curr Cancer Drug Targets. 2016;16(2):157-74. Review.

PMID:
26560116
9.

Functional diversity and structural disorder in the human ubiquitination pathway.

Bhowmick P, Pancsa R, Guharoy M, Tompa P.

PLoS One. 2013 May 29;8(5):e65443. doi: 10.1371/journal.pone.0065443. Print 2013.

10.

Human proteome-scale structural modeling of E2-E3 interactions exploiting interface motifs.

Kar G, Keskin O, Nussinov R, Gursoy A.

J Proteome Res. 2012 Feb 3;11(2):1196-207. doi: 10.1021/pr2009143. Epub 2012 Jan 10.

11.

RING domain E3 ubiquitin ligases.

Deshaies RJ, Joazeiro CA.

Annu Rev Biochem. 2009;78:399-434. doi: 10.1146/annurev.biochem.78.101807.093809. Review.

PMID:
19489725
12.

Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae.

Singh RK, Gonzalez M, Kabbaj MH, Gunjan A.

PLoS One. 2012;7(5):e36295. doi: 10.1371/journal.pone.0036295. Epub 2012 May 3.

13.

Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.

O'Connor HF, Lyon N, Leung JW, Agarwal P, Swaim CD, Miller KM, Huibregtse JM.

EMBO Rep. 2015 Dec;16(12):1699-712. doi: 10.15252/embr.201540620. Epub 2015 Oct 27.

14.

TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.

Kelsall IR, Duda DM, Olszewski JL, Hofmann K, Knebel A, Langevin F, Wood N, Wightman M, Schulman BA, Alpi AF.

EMBO J. 2013 Oct 30;32(21):2848-60. doi: 10.1038/emboj.2013.209. Epub 2013 Sep 27.

15.

Expansion and diversification of BTL ring-H2 ubiquitin ligases in angiosperms: putative Rabring7/BCA2 orthologs.

Aguilar-Hernández V, Medina J, Aguilar-Henonin L, Guzmán P.

PLoS One. 2013 Aug 8;8(8):e72729. doi: 10.1371/journal.pone.0072729. eCollection 2013.

16.

Working on a chain: E3s ganging up for ubiquitylation.

Metzger MB, Weissman AM.

Nat Cell Biol. 2010 Dec;12(12):1124-6. doi: 10.1038/ncb1210-1124.

PMID:
21124306
17.

Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.

Das R, Mariano J, Tsai YC, Kalathur RC, Kostova Z, Li J, Tarasov SG, McFeeters RL, Altieri AS, Ji X, Byrd RA, Weissman AM.

Mol Cell. 2009 Jun 26;34(6):674-85. doi: 10.1016/j.molcel.2009.05.010.

18.

Targeting E3 ubiquitin ligases for cancer therapy.

Sun Y.

Cancer Biol Ther. 2003 Nov-Dec;2(6):623-9. Review.

PMID:
14688465
19.

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases.

Zheng N, Wang P, Jeffrey PD, Pavletich NP.

Cell. 2000 Aug 18;102(4):533-9.

20.

Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

Pruneda JN, Littlefield PJ, Soss SE, Nordquist KA, Chazin WJ, Brzovic PS, Klevit RE.

Mol Cell. 2012 Sep 28;47(6):933-42. doi: 10.1016/j.molcel.2012.07.001. Epub 2012 Aug 9.

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