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Skin regeneration with conical and hair follicle structure of deep second-degree scalding injuries via combined expression of the EPO receptor and beta common receptor by local subcutaneous injection of nanosized rhEPO.

Bader A, Ebert S, Giri S, Kremer M, Liu S, Nerlich A, Günter CI, Smith DU, Machens HG.

Int J Nanomedicine. 2012;7:1227-37. doi: 10.2147/IJN.S28186. Epub 2012 Mar 6.


Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor.

Brines M, Grasso G, Fiordaliso F, Sfacteria A, Ghezzi P, Fratelli M, Latini R, Xie QW, Smart J, Su-Rick CJ, Pobre E, Diaz D, Gomez D, Hand C, Coleman T, Cerami A.

Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14907-12. Epub 2004 Sep 29.


Skin regeneration in deep second-degree scald injuries either by infusion pumping or topical application of recombinant human erythropoietin gel.

Giri P, Ebert S, Braumann UD, Kremer M, Giri S, Machens HG, Bader A.

Drug Des Devel Ther. 2015 May 11;9:2565-79. doi: 10.2147/DDDT.S79425. eCollection 2015.


EPO-independent functional EPO receptor in breast cancer enhances estrogen receptor activity and promotes cell proliferation.

Reinbothe S, Larsson AM, Vaapil M, Wigerup C, Sun J, Jögi A, Neumann D, Rönnstrand L, Påhlman S.

Biochem Biophys Res Commun. 2014 Feb 28;445(1):163-9. doi: 10.1016/j.bbrc.2014.01.165. Epub 2014 Feb 3.


β Common receptor integrates the erythropoietin signaling in activation of endothelial nitric oxide synthase.

Su KH, Shyue SK, Kou YR, Ching LC, Chiang AN, Yu YB, Chen CY, Pan CC, Lee TS.

J Cell Physiol. 2011 Dec;226(12):3330-9. doi: 10.1002/jcp.22678.


Erythropoietin promotes hair shaft growth in cultured human hair follicles and modulates hair growth in mice.

Kang BM, Shin SH, Kwack MH, Shin H, Oh JW, Kim J, Moon C, Moon C, Kim JC, Kim MK, Sung YK.

J Dermatol Sci. 2010 Aug;59(2):86-90. doi: 10.1016/j.jdermsci.2010.04.015. Epub 2010 May 19.


The erythropoietin/erythropoietin receptor signaling pathway promotes growth and invasion abilities in human renal carcinoma cells.

Wu P, Zhang N, Wang X, Zhang C, Li T, Ning X, Gong K.

PLoS One. 2012;7(9):e45122. doi: 10.1371/journal.pone.0045122. Epub 2012 Sep 18.


Optimal neuroprotection by erythropoietin requires elevated expression of its receptor in neurons.

Sanchez PE, Fares RP, Risso JJ, Bonnet C, Bouvard S, Le-Cavorsin M, Georges B, Moulin C, Belmeguenai A, Bodennec J, Morales A, Pequignot JM, Baulieu EE, Levine RA, Bezin L.

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9848-53. doi: 10.1073/pnas.0901840106. Epub 2009 Jun 3.


Erythropoietin attenuates cardiac dysfunction by increasing myocardial angiogenesis and inhibiting interstitial fibrosis in diabetic rats.

Lu J, Yao YY, Dai QM, Ma GS, Zhang SF, Cao L, Ren LQ, Liu NF.

Cardiovasc Diabetol. 2012 Sep 7;11:105. doi: 10.1186/1475-2840-11-105.


[Reproduction of a mouse model of deep partial-thickness scald and determination of hypoxia in the wound].

Zhang Y, Bai XZ, Lu S, Li N, Wang YC, Li XQ, Hu XL, Hu DH.

Zhonghua Shao Shang Za Zhi. 2013 Jun;29(3):277-80. Chinese.


Recombinant human erythropoietin administration protects cortical neurons from traumatic brain injury in rats.

Liao ZB, Zhi XG, Shi QH, He ZH.

Eur J Neurol. 2008 Feb;15(2):140-9. Epub 2007 Dec 18.


Erythropoietin improves histological and functional outcomes after traumatic brain injury in mice in the absence of the neural erythropoietin receptor.

Xiong Y, Mahmood A, Qu C, Kazmi H, Zhang ZG, Noguchi CT, Schallert T, Chopp M.

J Neurotrauma. 2010 Jan;27(1):205-15. doi: 10.1089/neu.2009.1001.


Differential neuroprotective properties of endogenous and exogenous erythropoietin in a mouse model of traumatic brain injury.

Shein NA, Grigoriadis N, Alexandrovich AG, Simeonidou C, Spandou E, Tsenter J, Yatsiv I, Horowitz M, Shohami E.

J Neurotrauma. 2008 Feb;25(2):112-23. doi: 10.1089/neu.2007.0358.


Intravitreal injection of erythropoietin protects both retinal vascular and neuronal cells in early diabetes.

Zhang J, Wu Y, Jin Y, Ji F, Sinclair SH, Luo Y, Xu G, Lu L, Dai W, Yanoff M, Li W, Xu GT.

Invest Ophthalmol Vis Sci. 2008 Feb;49(2):732-42. doi: 10.1167/iovs.07-0721.


A multi-center study on the regenerative effects of erythropoietin in burn and scalding injuries: study protocol for a randomized controlled trial.

Günter CI, Bader A, Dornseifer U, Egert S, Dunda S, Grieb G, Wolter T, Pallua N, von Wild T, Siemers F, Mailänder P, Thamm O, Ernert C, Steen M, Sievers R, Reichert B, Rahmanian-Schwarz A, Schaller H, Hartmann B, Otte M, Kehl V, Ohmann C, Jelkmann W, Machens HG.

Trials. 2013 May 3;14:124. doi: 10.1186/1745-6215-14-124.


Effects and mechanism of recombinant human erythropoietin on the growth of human breast cancer MDA-MB-231 cells in nude mice.

Jin W, Lin Z, Zhang X, Kong L, Yang L.

Pathol Res Pract. 2015 Aug;211(8):570-6. doi: 10.1016/j.prp.2015.04.006. Epub 2015 Apr 24.


Epoetin Alpha and Epoetin Zeta: A Comparative Study on Stimulation of Angiogenesis and Wound Repair in an Experimental Model of Burn Injury.

Irrera N, Bitto A, Pizzino G, Vaccaro M, Squadrito F, Galeano M, Stagno d'Alcontres F, Stagno d'Alcontres F, Buemi M, Minutoli L, Colonna MR, Altavilla D.

Biomed Res Int. 2015;2015:968927. doi: 10.1155/2015/968927. Epub 2015 Jun 4.


Helix B surface peptide administered after insult of ischemia reperfusion improved renal function, structure and apoptosis through beta common receptor/erythropoietin receptor and PI3K/Akt pathway in a murine model.

Yang C, Zhao T, Lin M, Zhao Z, Hu L, Jia Y, Xue Y, Xu M, Tang Q, Yang B, Rong R, Zhu T.

Exp Biol Med (Maywood). 2013 Jan;238(1):111-9. doi: 10.1258/ebm.2012.012185.


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