Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 144


Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling.

Subramaniam N, Sherman MH, Rao R, Wilson C, Coulter S, Atkins AR, Evans RM, Liddle C, Downes M.

Cancer Prev Res (Phila). 2012 Apr;5(4):553-61. doi: 10.1158/1940-6207.CAPR-12-0053. Epub 2012 Mar 9.


Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.

Langelueddecke C, Jakab M, Ketterl N, Lehner L, Hufnagl C, Schmidt S, Geibel JP, Fuerst J, Ritter M.

Cell Physiol Biochem. 2012;29(1-2):75-86. doi: 10.1159/000337589. Epub 2012 Mar 1.


AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

Sajan MP, Bandyopadhyay G, Miura A, Standaert ML, Nimal S, Longnus SL, Van Obberghen E, Hainault I, Foufelle F, Kahn R, Braun U, Leitges M, Farese RV.

Am J Physiol Endocrinol Metab. 2010 Feb;298(2):E179-92. doi: 10.1152/ajpendo.00392.2009. Epub 2009 Nov 3.


AMP-activated protein kinase inhibits TGF-β-induced fibrogenic responses of hepatic stellate cells by targeting transcriptional coactivator p300.

Lim JY, Oh MA, Kim WH, Sohn HY, Park SI.

J Cell Physiol. 2012 Mar;227(3):1081-9. doi: 10.1002/jcp.22824.


5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo.

Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH.

J Biol Chem. 2014 Feb 28;289(9):5950-9. doi: 10.1074/jbc.M113.528232. Epub 2014 Jan 8.


AICAR, an activator of AMPK, inhibits adipogenesis via the WNT/β-catenin pathway in 3T3-L1 adipocytes.

Lee H, Kang R, Bae S, Yoon Y.

Int J Mol Med. 2011 Jul;28(1):65-71. doi: 10.3892/ijmm.2011.674. Epub 2011 Apr 13.


Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells.

Turban S, Stretton C, Drouin O, Green CJ, Watson ML, Gray A, Ross F, Lantier L, Viollet B, Hardie DG, Marette A, Hundal HS.

J Biol Chem. 2012 Jun 8;287(24):20088-99. doi: 10.1074/jbc.M111.330746. Epub 2012 Apr 17.


Wnt/β-Catenin Mediates AICAR Effect to Increase GATA3 Expression and Inhibit Adipogenesis.

Wang L, Di LJ.

J Biol Chem. 2015 Aug 7;290(32):19458-68. doi: 10.1074/jbc.M115.641332. Epub 2015 Jun 24. Erratum in: J Biol Chem. 2015 Dec 11;290(50):29759.


5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes.

Ségalen C, Longnus SL, Baetz D, Counillon L, Van Obberghen E.

Endocrinology. 2008 Apr;149(4):1490-8. doi: 10.1210/en.2007-1326. Epub 2008 Jan 10.


AICAR and Metformin Exert AMPK-dependent Effects on INS-1E Pancreatic β-cell Apoptosis via Differential Downstream Mechanisms.

Dai YL, Huang SL, Leng Y.

Int J Biol Sci. 2015 Sep 14;11(11):1272-80. doi: 10.7150/ijbs.12108. eCollection 2015.


Small heterodimer partner attenuates profibrogenic features of hepatitis C virus-infected cells.

Jung GS, Jeon JH, Choi YK, Jang SY, Park SY, Kim MK, Shin EC, Jeong WI, Lee IK, Kang YN, Park KG.

Liver Int. 2015 Oct;35(10):2233-45. doi: 10.1111/liv.12871. Epub 2015 Jun 3.


Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats.

Jiang SJ, Dong H, Li JB, Xu LJ, Zou X, Wang KF, Lu FE, Yi P.

World J Gastroenterol. 2015 Jul 7;21(25):7777-85. doi: 10.3748/wjg.v21.i25.7777.


Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

Sakamoto K, Göransson O, Hardie DG, Alessi DR.

Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E310-7. Epub 2004 Apr 6.


AICAR induces astroglial differentiation of neural stem cells via activating the JAK/STAT3 pathway independently of AMP-activated protein kinase.

Zang Y, Yu LF, Pang T, Fang LP, Feng X, Wen TQ, Nan FJ, Feng LY, Li J.

J Biol Chem. 2008 Mar 7;283(10):6201-8. Epub 2007 Dec 12.


Role of AMP-activated protein kinase in mechanism of metformin action.

Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE.

J Clin Invest. 2001 Oct;108(8):1167-74.


Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR).

Zhuge J.

Cell Biol Toxicol. 2009 Jun;25(3):253-63. doi: 10.1007/s10565-008-9075-9. Epub 2008 May 13.

Items per page

Supplemental Content

Write to the Help Desk