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Items: 1 to 20 of 152

1.

Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling.

Subramaniam N, Sherman MH, Rao R, Wilson C, Coulter S, Atkins AR, Evans RM, Liddle C, Downes M.

Cancer Prev Res (Phila). 2012 Apr;5(4):553-61. doi: 10.1158/1940-6207.CAPR-12-0053. Epub 2012 Mar 9.

2.

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.

Sajan MP, Bandyopadhyay G, Miura A, Standaert ML, Nimal S, Longnus SL, Van Obberghen E, Hainault I, Foufelle F, Kahn R, Braun U, Leitges M, Farese RV.

Am J Physiol Endocrinol Metab. 2010 Feb;298(2):E179-92. doi: 10.1152/ajpendo.00392.2009. Epub 2009 Nov 3.

3.

Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.

Langelueddecke C, Jakab M, Ketterl N, Lehner L, Hufnagl C, Schmidt S, Geibel JP, Fuerst J, Ritter M.

Cell Physiol Biochem. 2012;29(1-2):75-86. doi: 10.1159/000337589. Epub 2012 Mar 1.

4.

AMP-activated protein kinase inhibits TGF-β-induced fibrogenic responses of hepatic stellate cells by targeting transcriptional coactivator p300.

Lim JY, Oh MA, Kim WH, Sohn HY, Park SI.

J Cell Physiol. 2012 Mar;227(3):1081-9. doi: 10.1002/jcp.22824.

PMID:
21567395
5.

Metformin ameliorates activation of hepatic stellate cells and hepatic fibrosis by succinate and GPR91 inhibition.

Nguyen G, Park SY, Le CT, Park WS, Choi DH, Cho EH.

Biochem Biophys Res Commun. 2018 Jan 22;495(4):2649-2656. doi: 10.1016/j.bbrc.2017.12.143. Epub 2017 Dec 24.

PMID:
29278707
6.

Wnt/β-Catenin Mediates AICAR Effect to Increase GATA3 Expression and Inhibit Adipogenesis.

Wang L, Di LJ.

J Biol Chem. 2015 Aug 7;290(32):19458-68. doi: 10.1074/jbc.M115.641332. Epub 2015 Jun 24. Erratum in: J Biol Chem. 2015 Dec 11;290(50):29759.

7.

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo.

Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH.

J Biol Chem. 2014 Feb 28;289(9):5950-9. doi: 10.1074/jbc.M113.528232. Epub 2014 Jan 8.

8.

AICAR and Metformin Exert AMPK-dependent Effects on INS-1E Pancreatic β-cell Apoptosis via Differential Downstream Mechanisms.

Dai YL, Huang SL, Leng Y.

Int J Biol Sci. 2015 Sep 14;11(11):1272-80. doi: 10.7150/ijbs.12108. eCollection 2015.

9.

AICAR, an activator of AMPK, inhibits adipogenesis via the WNT/β-catenin pathway in 3T3-L1 adipocytes.

Lee H, Kang R, Bae S, Yoon Y.

Int J Mol Med. 2011 Jul;28(1):65-71. doi: 10.3892/ijmm.2011.674. Epub 2011 Apr 13.

PMID:
21491080
10.
11.

Small heterodimer partner attenuates profibrogenic features of hepatitis C virus-infected cells.

Jung GS, Jeon JH, Choi YK, Jang SY, Park SY, Kim MK, Shin EC, Jeong WI, Lee IK, Kang YN, Park KG.

Liver Int. 2015 Oct;35(10):2233-45. doi: 10.1111/liv.12871. Epub 2015 Jun 3.

PMID:
25976932
12.
13.

5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes.

Ségalen C, Longnus SL, Baetz D, Counillon L, Van Obberghen E.

Endocrinology. 2008 Apr;149(4):1490-8. doi: 10.1210/en.2007-1326. Epub 2008 Jan 10.

PMID:
18187546
14.

Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats.

Jiang SJ, Dong H, Li JB, Xu LJ, Zou X, Wang KF, Lu FE, Yi P.

World J Gastroenterol. 2015 Jul 7;21(25):7777-85. doi: 10.3748/wjg.v21.i25.7777.

15.

Metformin and AICAR regulate NANOG expression via the JNK pathway in HepG2 cells independently of AMPK.

Shen C, Ka SO, Kim SJ, Kim JH, Park BH, Park JH.

Tumour Biol. 2016 Aug;37(8):11199-208. doi: 10.1007/s13277-016-5007-0. Epub 2016 Mar 3.

PMID:
26939902
16.
17.

AICAR induces astroglial differentiation of neural stem cells via activating the JAK/STAT3 pathway independently of AMP-activated protein kinase.

Zang Y, Yu LF, Pang T, Fang LP, Feng X, Wen TQ, Nan FJ, Feng LY, Li J.

J Biol Chem. 2008 Mar 7;283(10):6201-8. Epub 2007 Dec 12.

18.

Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

Sakamoto K, Göransson O, Hardie DG, Alessi DR.

Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E310-7. Epub 2004 Apr 6.

19.

AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3).

Nerstedt A, Johansson A, Andersson CX, Cansby E, Smith U, Mahlapuu M.

Diabetologia. 2010 Nov;53(11):2406-16. doi: 10.1007/s00125-010-1856-z. Epub 2010 Jul 24.

PMID:
20652679
20.

Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells.

Woollhead AM, Sivagnanasundaram J, Kalsi KK, Pucovsky V, Pellatt LJ, Scott JW, Mustard KJ, Hardie DG, Baines DL.

Br J Pharmacol. 2007 Aug;151(8):1204-15. Epub 2007 Jul 2.

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