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Studies on HOXB4 expression during differentiation of human cytomegalovirus-infected hematopoietic stem cells into lymphocyte and erythrocyte progenitor cells.

Wen-jun L, qu-lian G, Hong-ying C, Yan Z, Mei-Xian H.

Cell Biochem Biophys. 2012 Jun;63(2):133-41. doi: 10.1007/s12013-012-9349-y.


Effect of human cytomegalovirus infection on the expression of Hoxb2 and Hoxb4 genes in the developmental process of cord blood erythroid progenitors.

Liu WJ, Huang MX, Guo QL, Chen JH, Shi H.

Mol Med Rep. 2011 Nov-Dec;4(6):1307-11. doi: 10.3892/mmr.2011.576. Epub 2011 Aug 30.


Effect of human cytomegalovirus on proliferation of hematopoietic progenitor cells of cord blood.

Liu WJ, Jin RM, Fu XD, Liu B, Guo QL, Deng ZH.

Zhongguo Dang Dai Er Ke Za Zhi. 2006 Apr;8(2):85-9.


[Effect of human cytomegalovirus infection on the expression of hoxc4 and hoxc6 genes in the proliferation of lymphocytic progenitor cells].

Feng JQ, Liu WJ, Chen HY, Guo QL, Chen A, Chen SQ.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Feb;17(1):141-5. Chinese.


[Effect of ATRA on the expression of genes Hoxb2 and Hoxb4 in cord blood erythroid progenitors].

DU CQ, Huang MX, Liu WJ.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Dec;17(6):1516-21. Chinese.


High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation.

Schiedlmeier B, Klump H, Will E, Arman-Kalcek G, Li Z, Wang Z, Rimek A, Friel J, Baum C, Ostertag W.

Blood. 2003 Mar 1;101(5):1759-68. Epub 2002 Oct 24.


Stromal cells selectively reduce the growth advantage of human committed CD34+ hematopoietic cells ectopically expressing HOXB4.

Friel J, Schiedlmeier B, Geldmacher M, Ostertag W.

Growth Factors. 2006 Jun;24(2):97-105.


[Human cytomegalovirus inhibits the proliferation of CFU-MK in vitro].

Pan S, He Z, Chen F, Wang Q, Zou X, Huang L, Yang M.

Zhonghua Xue Ye Xue Za Zhi. 2001 Mar;22(3):135-7. Chinese.


Lentiviral-mediated HoxB4 expression in human embryonic stem cells initiates early hematopoiesis in a dose-dependent manner but does not promote myeloid differentiation.

Unger C, Kärner E, Treschow A, Stellan B, Felldin U, Concha H, Wendel M, Hovatta O, Aints A, Ahrlund-Richter L, Dilber MS.

Stem Cells. 2008 Oct;26(10):2455-66. doi: 10.1634/stemcells.2007-0876. Epub 2008 Jul 10.


Effects of HOXB4 overexpression on ex vivo expansion and immortalization of hematopoietic cells from different species.

Zhang XB, Schwartz JL, Humphries RK, Kiem HP.

Stem Cells. 2007 Aug;25(8):2074-81. Epub 2007 May 17.


Direct growth suppression of myeloid bone marrow progenitor cells but not cord blood progenitors by human cytomegalovirus in vitro.

Holberg-Petersen M, Rollag H, Beck S, Overli I, Tjønnfjord G, Abrahamsen TG, Degré M, Hestdal K.

Blood. 1996 Oct 1;88(7):2510-6.


Human cytomegalovirus suppression of and latency in early hematopoietic progenitor cells.

Sindre H, Tjøonnfjord GE, Rollag H, Ranneberg-Nilsen T, Veiby OP, Beck S, Degré M, Hestdal K.

Blood. 1996 Dec 15;88(12):4526-33.


Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential.

Ohno Y, Yasunaga S, Ohtsubo M, Mori S, Tsumura M, Okada S, Ohta T, Ohtani K, Kobayashi M, Takihara Y.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21529-34. doi: 10.1073/pnas.1011054107. Epub 2010 Nov 22.


Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.

Jackson M, Ma R, Taylor AH, Axton RA, Easterbrook J, Kydonaki M, Olivier E, Marenah L, Stanley EG, Elefanty AG, Mountford JC, Forrester LM.

Stem Cells Transl Med. 2016 Aug;5(8):981-90. doi: 10.5966/sctm.2015-0324. Epub 2016 Jun 28.


Dual action of retinoic acid on human embryonic/fetal hematopoiesis: blockade of primitive progenitor proliferation and shift from multipotent/erythroid/monocytic to granulocytic differentiation program.

Tocci A, Parolini I, Gabbianelli M, Testa U, Luchetti L, Samoggia P, Masella B, Russo G, Valtieri M, Peschle C.

Blood. 1996 Oct 15;88(8):2878-88.


Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells.

Brun AC, Björnsson JM, Magnusson M, Larsson N, Leveén P, Ehinger M, Nilsson E, Karlsson S.

Blood. 2004 Jun 1;103(11):4126-33. Epub 2004 Feb 12.

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