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Items: 1 to 20 of 179

1.

Osteopontin in systemic sclerosis and its role in dermal fibrosis.

Wu M, Schneider DJ, Mayes MD, Assassi S, Arnett FC, Tan FK, Blackburn MR, Agarwal SK.

J Invest Dermatol. 2012 Jun;132(6):1605-14. doi: 10.1038/jid.2012.32.

2.

CD109 overexpression ameliorates skin fibrosis in a mouse model of bleomycin-induced scleroderma.

Vorstenbosch J, Al-Ajmi H, Winocour S, Trzeciak A, Lessard L, Philip A.

Arthritis Rheum. 2013 May;65(5):1378-83. doi: 10.1002/art.37907.

3.

Identification of cadherin 11 as a mediator of dermal fibrosis and possible role in systemic sclerosis.

Wu M, Pedroza M, Lafyatis R, George AT, Mayes MD, Assassi S, Tan FK, Brenner MB, Agarwal SK.

Arthritis Rheumatol. 2014 Apr;66(4):1010-21. doi: 10.1002/art.38275.

4.

Sustained activation of fibroblast transforming growth factor-beta/Smad signaling in a murine model of scleroderma.

Takagawa S, Lakos G, Mori Y, Yamamoto T, Nishioka K, Varga J.

J Invest Dermatol. 2003 Jul;121(1):41-50.

5.

Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.

Tomcik M, Palumbo-Zerr K, Zerr P, Sumova B, Avouac J, Dees C, Distler A, Becvar R, Distler O, Schett G, Senolt L, Distler JH.

Ann Rheum Dis. 2016 Mar;75(3):609-16. doi: 10.1136/annrheumdis-2014-206234.

PMID:
25603829
6.

Activation of pregnane X receptor inhibits experimental dermal fibrosis.

Beyer C, Skapenko A, Distler A, Dees C, Reichert H, Munoz L, Leipe J, Schulze-Koops H, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2013 Apr;72(4):621-5. doi: 10.1136/annrheumdis-2012-202476.

PMID:
23291432
7.

The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.

Avouac J, Palumbo-Zerr K, Ruzehaji N, Tomcik M, Zerr P, Dees C, Distler A, Beyer C, Schneider H, Distler O, Schett G, Allanore Y, Distler JH.

Arthritis Rheumatol. 2014 Nov;66(11):3140-50. doi: 10.1002/art.38819.

8.

Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice.

Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, Toyama T, Trojanowska M, Sato S.

Arthritis Rheumatol. 2015 Feb;67(2):517-26. doi: 10.1002/art.38948.

9.

Is osteopontin involved in cutaneous fibroblast activation? Its hypothetical role in scleroderma pathogenesis.

Corallo C, Volpi N, Franci D, Montella A, Biagioli M, Mariotti G, D'Onofrio F, Gonnelli S, Nuti R, Giordano N.

Int J Immunopathol Pharmacol. 2014 Jan-Mar;27(1):97-102.

PMID:
24674683
10.

Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma.

Lakos G, Takagawa S, Chen SJ, Ferreira AM, Han G, Masuda K, Wang XJ, DiPietro LA, Varga J.

Am J Pathol. 2004 Jul;165(1):203-17.

11.

S100A4 amplifies TGF-β-induced fibroblast activation in systemic sclerosis.

Tomcik M, Palumbo-Zerr K, Zerr P, Avouac J, Dees C, Sumova B, Distler A, Beyer C, Cerezo LA, Becvar R, Distler O, Grigorian M, Schett G, Senolt L, Distler JH.

Ann Rheum Dis. 2015 Sep;74(9):1748-55. doi: 10.1136/annrheumdis-2013-204516.

PMID:
24709861
12.

Osteopontin expression is required for myofibroblast differentiation.

Lenga Y, Koh A, Perera AS, McCulloch CA, Sodek J, Zohar R.

Circ Res. 2008 Feb 15;102(3):319-27.

13.

Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.

Tomcik M, Zerr P, Pitkowski J, Palumbo-Zerr K, Avouac J, Distler O, Becvar R, Senolt L, Schett G, Distler JH.

Ann Rheum Dis. 2014 Jun;73(6):1215-22. doi: 10.1136/annrheumdis-2012-203095.

PMID:
23661493
14.

Vascular endothelial growth factor aggravates fibrosis and vasculopathy in experimental models of systemic sclerosis.

Maurer B, Distler A, Suliman YA, Gay RE, Michel BA, Gay S, Distler JH, Distler O.

Ann Rheum Dis. 2014 Oct;73(10):1880-7. doi: 10.1136/annrheumdis-2013-203535.

PMID:
23918036
15.

Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.

Avouac J, Palumbo K, Tomcik M, Zerr P, Dees C, Horn A, Maurer B, Akhmetshina A, Beyer C, Sadowski A, Schneider H, Shiozawa S, Distler O, Schett G, Allanore Y, Distler JH.

Arthritis Rheum. 2012 May;64(5):1642-52. doi: 10.1002/art.33501.

16.

Alpha2-antiplasmin regulates the development of dermal fibrosis in mice by prostaglandin F(2α) synthesis through adipose triglyceride lipase/calcium-independent phospholipase A(2).

Kanno Y, Kawashita E, Kokado A, Okada K, Ueshima S, Matsuo O, Matsuno H.

Arthritis Rheum. 2013 Feb;65(2):492-502. doi: 10.1002/art.37767. Erratum in: Arthritis Rheum. 2014 Jun;66(6):1671.

17.

Increased expression of chemerin in endothelial cells due to Fli1 deficiency may contribute to the development of digital ulcers in systemic sclerosis.

Akamata K, Asano Y, Taniguchi T, Yamashita T, Saigusa R, Nakamura K, Noda S, Aozasa N, Toyama T, Takahashi T, Ichimura Y, Sumida H, Tada Y, Sugaya M, Kadono T, Sato S.

Rheumatology (Oxford). 2015 Jul;54(7):1308-16. doi: 10.1093/rheumatology/keu479.

18.

Periostin facilitates skin sclerosis via PI3K/Akt dependent mechanism in a mouse model of scleroderma.

Yang L, Serada S, Fujimoto M, Terao M, Kotobuki Y, Kitaba S, Matsui S, Kudo A, Naka T, Murota H, Katayama I.

PLoS One. 2012;7(7):e41994. doi: 10.1371/journal.pone.0041994.

19.

The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.

Reich N, Maurer B, Akhmetshina A, Venalis P, Dees C, Zerr P, Palumbo K, Zwerina J, Nevskaya T, Gay S, Distler O, Schett G, Distler JH.

Arthritis Rheum. 2010 Jan;62(1):280-90. doi: 10.1002/art.25056.

20.

Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis.

Zerr P, Palumbo-Zerr K, Huang J, Tomcik M, Sumova B, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2016 Jan;75(1):226-33. doi: 10.1136/annrheumdis-2014-205740.

PMID:
25180292
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