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Items: 1 to 20 of 166


Larazotide acetate regulates epithelial tight junctions in vitro and in vivo.

Gopalakrishnan S, Durai M, Kitchens K, Tamiz AP, Somerville R, Ginski M, Paterson BM, Murray JA, Verdu EF, Alkan SS, Pandey NB.

Peptides. 2012 May;35(1):86-94. doi: 10.1016/j.peptides.2012.02.015. Epub 2012 Feb 27.


Larazotide acetate promotes tight junction assembly in epithelial cells.

Gopalakrishnan S, Tripathi A, Tamiz AP, Alkan SS, Pandey NB.

Peptides. 2012 May;35(1):95-101. doi: 10.1016/j.peptides.2012.02.016. Epub 2012 Feb 28.


Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines.

Drago S, El Asmar R, Di Pierro M, Grazia Clemente M, Tripathi A, Sapone A, Thakar M, Iacono G, Carroccio A, D'Agate C, Not T, Zampini L, Catassi C, Fasano A.

Scand J Gastroenterol. 2006 Apr;41(4):408-19.


The active Zot domain (aa 288-293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation.

Goldblum SE, Rai U, Tripathi A, Thakar M, De Leo L, Di Toro N, Not T, Ramachandran R, Puche AC, Hollenberg MD, Fasano A.

FASEB J. 2011 Jan;25(1):144-58. doi: 10.1096/fj.10-158972. Epub 2010 Sep 17.


Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer.

Gopalakrishnan S, Pandey N, Tamiz AP, Vere J, Carrasco R, Somerville R, Tripathi A, Ginski M, Paterson BM, Alkan SS.

Int J Pharm. 2009 Jan 5;365(1-2):121-30. doi: 10.1016/j.ijpharm.2008.08.047. Epub 2008 Sep 11.


Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function.

Hopkins AM, Walsh SV, Verkade P, Boquet P, Nusrat A.

J Cell Sci. 2003 Feb 15;116(Pt 4):725-42.


Lactobacillus GG restoration of the gliadin induced epithelial barrier disruption: the role of cellular polyamines.

Orlando A, Linsalata M, Notarnicola M, Tutino V, Russo F.

BMC Microbiol. 2014 Jan 31;14:19. doi: 10.1186/1471-2180-14-19.


Rapid disruption of intestinal barrier function by gliadin involves altered expression of apical junctional proteins.

Sander GR, Cummins AG, Henshall T, Powell BC.

FEBS Lett. 2005 Aug 29;579(21):4851-5.


Mechanism of extracellular calcium regulation of intestinal epithelial tight junction permeability: role of cytoskeletal involvement.

Ma TY, Tran D, Hoa N, Nguyen D, Merryfield M, Tarnawski A.

Microsc Res Tech. 2000 Oct 15;51(2):156-68.


A randomized, double-blind study of larazotide acetate to prevent the activation of celiac disease during gluten challenge.

Leffler DA, Kelly CP, Abdallah HZ, Colatrella AM, Harris LA, Leon F, Arterburn LA, Paterson BM, Lan ZH, Murray JA.

Am J Gastroenterol. 2012 Oct;107(10):1554-62. doi: 10.1038/ajg.2012.211. Epub 2012 Jul 24.


Cytochalasin B modulation of Caco-2 tight junction barrier: role of myosin light chain kinase.

Ma TY, Hoa NT, Tran DD, Bui V, Pedram A, Mills S, Merryfield M.

Am J Physiol Gastrointest Liver Physiol. 2000 Nov;279(5):G875-85.


Roles of ZO-1, occludin, and actin in oxidant-induced barrier disruption.

Musch MW, Walsh-Reitz MM, Chang EB.

Am J Physiol Gastrointest Liver Physiol. 2006 Feb;290(2):G222-31. Epub 2005 Oct 20.


TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation.

Ma TY, Iwamoto GK, Hoa NT, Akotia V, Pedram A, Boivin MA, Said HM.

Am J Physiol Gastrointest Liver Physiol. 2004 Mar;286(3):G367-76.


Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3.

Lammers KM, Lu R, Brownley J, Lu B, Gerard C, Thomas K, Rallabhandi P, Shea-Donohue T, Tamiz A, Alkan S, Netzel-Arnett S, Antalis T, Vogel SN, Fasano A.

Gastroenterology. 2008 Jul;135(1):194-204.e3. doi: 10.1053/j.gastro.2008.03.023. Epub 2008 Mar 21.


Sodium caprate transiently opens claudin-5-containing barriers at tight junctions of epithelial and endothelial cells.

Del Vecchio G, Tscheik C, Tenz K, Helms HC, Winkler L, Blasig R, Blasig IE.

Mol Pharm. 2012 Sep 4;9(9):2523-33. doi: 10.1021/mp3001414. Epub 2012 Aug 21.


Live probiotic Bifidobacterium lactis bacteria inhibit the toxic effects induced by wheat gliadin in epithelial cell culture.

Lindfors K, Blomqvist T, Juuti-Uusitalo K, Stenman S, Venäläinen J, Mäki M, Kaukinen K.

Clin Exp Immunol. 2008 Jun;152(3):552-8. doi: 10.1111/j.1365-2249.2008.03635.x. Epub 2008 Apr 16.


Melittin as an epithelial permeability enhancer I: investigation of its mechanism of action in Caco-2 monolayers.

Maher S, Feighery L, Brayden DJ, McClean S.

Pharm Res. 2007 Jul;24(7):1336-45. Epub 2007 Mar 21.


AMP-18 protects barrier function of colonic epithelial cells: role of tight junction proteins.

Walsh-Reitz MM, Huang EF, Musch MW, Chang EB, Martin TE, Kartha S, Toback FG.

Am J Physiol Gastrointest Liver Physiol. 2005 Jul;289(1):G163-71.


Disruption of epithelial tight junctions is prevented by cyclic nucleotide-dependent protein kinase inhibitors.

Klingler C, Kniesel U, Bamforth SD, Wolburg H, Engelhardt B, Risau W.

Histochem Cell Biol. 2000 May;113(5):349-61.

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