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Items: 1 to 20 of 104

1.

Notch inhibition as a promising new approach to cancer therapy.

Purow B.

Adv Exp Med Biol. 2012;727:305-19. doi: 10.1007/978-1-4614-0899-4_23. Review.

2.

Notch inhibitors for cancer treatment.

Espinoza I, Miele L.

Pharmacol Ther. 2013 Aug;139(2):95-110. doi: 10.1016/j.pharmthera.2013.02.003. Epub 2013 Feb 28. Review.

3.

Notch signaling: an emerging therapeutic target for cancer treatment.

Yuan X, Wu H, Xu H, Xiong H, Chu Q, Yu S, Wu GS, Wu K.

Cancer Lett. 2015 Dec 1;369(1):20-7. doi: 10.1016/j.canlet.2015.07.048. Epub 2015 Sep 1. Review.

4.

Notch inhibitors as a new tool in the war on cancer: a pathway to watch.

Purow B.

Curr Pharm Biotechnol. 2009 Feb;10(2):154-60. Review.

5.

Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.

Groth C, Fortini ME.

Semin Cell Dev Biol. 2012 Jun;23(4):465-72. doi: 10.1016/j.semcdb.2012.01.016. Epub 2012 Jan 30. Review.

6.

Notch signaling in cancer.

Miele L, Golde T, Osborne B.

Curr Mol Med. 2006 Dec;6(8):905-18. Review.

PMID:
17168741
7.

Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

Konishi J, Kawaguchi KS, Vo H, Haruki N, Gonzalez A, Carbone DP, Dang TP.

Cancer Res. 2007 Sep 1;67(17):8051-7.

8.

NOTCH signaling as a novel cancer therapeutic target.

Miele L, Miao H, Nickoloff BJ.

Curr Cancer Drug Targets. 2006 Jun;6(4):313-23. Review.

PMID:
16848722
9.

Regulation of EMT by Notch signaling pathway in tumor progression.

Li Y, Ma J, Qian X, Wu Q, Xia J, Miele L, Sarkar FH, Wang Z.

Curr Cancer Drug Targets. 2013 Nov;13(9):957-62. Review.

PMID:
24168187
10.

Targeting notch signaling pathway in cancer: clinical development advances and challenges.

Takebe N, Nguyen D, Yang SX.

Pharmacol Ther. 2014 Feb;141(2):140-9. doi: 10.1016/j.pharmthera.2013.09.005. Epub 2013 Sep 27. Review.

11.

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways.

Takebe N, Harris PJ, Warren RQ, Ivy SP.

Nat Rev Clin Oncol. 2011 Feb;8(2):97-106. doi: 10.1038/nrclinonc.2010.196. Epub 2010 Dec 14. Review.

PMID:
21151206
12.

Mechanisms and clinical prospects of Notch inhibitors in the therapy of hematological malignancies.

Nefedova Y, Gabrilovich D.

Drug Resist Updat. 2008 Dec;11(6):210-8. doi: 10.1016/j.drup.2008.09.002. Epub 2008 Oct 31. Review.

13.

Notch Signaling in Cancer: Rationale and Strategies for Targeting.

Alketbi A, Attoub S.

Curr Cancer Drug Targets. 2015;15(5):364-74. Review.

PMID:
26239151
14.

Notch regulation of tumor angiogenesis.

Bridges E, Oon CE, Harris A.

Future Oncol. 2011 Apr;7(4):569-88. doi: 10.2217/fon.11.20. Review.

PMID:
21463145
15.

Notch inhibitors and their role in the treatment of triple negative breast cancer: promises and failures.

Locatelli M, Curigliano G.

Curr Opin Oncol. 2017 Nov;29(6):411-427. doi: 10.1097/CCO.0000000000000406. Review.

PMID:
28914645
16.

Notch signaling in breast cancer and tumor angiogenesis: cross-talk and therapeutic potentials.

Shi W, Harris AL.

J Mammary Gland Biol Neoplasia. 2006 Jan;11(1):41-52. Review.

PMID:
16947085
17.

Therapeutic antibody targeting of individual Notch receptors.

Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, Zhang J, Choy R, Howard P, Kadyk L, Yan M, Zha J, Callahan CA, Hymowitz SG, Siebel CW.

Nature. 2010 Apr 15;464(7291):1052-7. doi: 10.1038/nature08878.

PMID:
20393564
18.

Notch Antagonists: Potential Modulators of Cancer and Inflammatory Diseases.

Kumar R, Juillerat-Jeanneret L, Golshayan D.

J Med Chem. 2016 Sep 8;59(17):7719-37. doi: 10.1021/acs.jmedchem.5b01516. Epub 2016 Apr 18. Review.

PMID:
27045975
19.

Molecular pathways: translational and therapeutic implications of the Notch signaling pathway in cancer.

Previs RA, Coleman RL, Harris AL, Sood AK.

Clin Cancer Res. 2015 Mar 1;21(5):955-61. doi: 10.1158/1078-0432.CCR-14-0809. Epub 2014 Nov 11. Review.

20.

Role of Notch signalling pathway in cancer and its association with DNA methylation.

Aithal MG, Rajeswari N.

J Genet. 2013 Dec;92(3):667-75. Review.

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