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Cell surface localization and release of the candidate tumor suppressor Ecrg4 from polymorphonuclear cells and monocytes activate macrophages.

Baird A, Coimbra R, Dang X, Lopez N, Lee J, Krzyzaniak M, Winfield R, Potenza B, Eliceiri BP.

J Leukoc Biol. 2012 May;91(5):773-81. doi: 10.1189/jlb.1011503. Epub 2012 Mar 6.


Monitoring Neutrophil-Expressed Cell Surface Esophageal Cancer Related Gene-4 after Severe Burn Injury.

Costantini TW, Coimbra R, Lopez NE, Lee JG, Potenza B, Smith A, Baird A, Eliceiri BP.

Surg Infect (Larchmt). 2015 Dec;16(6):669-74. doi: 10.1089/sur.2014.209. Epub 2015 Oct 13.


Pulmonary preconditioning, injury, and inflammation modulate expression of the candidate tumor suppressor gene ECRG4 in lung.

Kao S, Shaterian A, Cauvi DM, Dang X, Chun HB, De Maio A, Costantini TW, Coimbra R, Eliceiri BP, Baird A.

Exp Lung Res. 2015 Apr;41(3):162-72. doi: 10.3109/01902148.2014.983282. Epub 2014 Dec 16.


ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma.

Götze S, Feldhaus V, Traska T, Wolter M, Reifenberger G, Tannapfel A, Kuhnen C, Martin D, Müller O, Sievers S.

BMC Cancer. 2009 Dec 17;9:447. doi: 10.1186/1471-2407-9-447.


Cell-specific processing and release of the hormone-like precursor and candidate tumor suppressor gene product, Ecrg4.

Dang X, Podvin S, Coimbra R, Eliceiri B, Baird A.

Cell Tissue Res. 2012 Jun;348(3):505-14. doi: 10.1007/s00441-012-1396-6. Epub 2012 Apr 18.


The candidate tumor suppressor gene ECRG4 inhibits cancer cells migration and invasion in esophageal carcinoma.

Li L, Zhang C, Li X, Lu S, Zhou Y.

J Exp Clin Cancer Res. 2010 Oct 11;29:133. doi: 10.1186/1756-9966-29-133. Retraction in: J Exp Clin Cancer Res. 2011;30:19.


The candidate tumor suppressor gene Ecrg4 as a wound terminating factor in cutaneous injury.

Shaterian A, Kao S, Chen L, DiPietro LA, Coimbra R, Eliceiri BP, Baird A.

Arch Dermatol Res. 2013 Mar;305(2):141-9. doi: 10.1007/s00403-012-1276-7. Epub 2012 Aug 17.


ECRG4 acts as a tumor suppressor and as a determinant of chemotherapy resistance in human nasopharyngeal carcinoma.

You Y, Yang W, Qin X, Wang F, Li H, Lin C, Li W, Gu C, Zhang Y, Ran Y.

Cell Oncol (Dordr). 2015 Jun;38(3):205-14. doi: 10.1007/s13402-015-0223-y. Epub 2015 Feb 24.


Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion.

Li W, Liu X, Zhang B, Qi D, Zhang L, Jin Y, Yang H.

J Exp Clin Cancer Res. 2010 Jul 4;29:89. doi: 10.1186/1756-9966-29-89.


Esophageal cancer related gene-4 is a choroid plexus-derived injury response gene: evidence for a biphasic response in early and late brain injury.

Podvin S, Gonzalez AM, Miller MC, Dang X, Botfield H, Donahue JE, Kurabi A, Boissaud-Cooke M, Rossi R, Leadbeater WE, Johanson CE, Coimbra R, Stopa EG, Eliceiri BP, Baird A.

PLoS One. 2011;6(9):e24609. doi: 10.1371/journal.pone.0024609. Epub 2011 Sep 14.


A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma.

Li LW, Li YY, Li XY, Zhang CP, Zhou Y, Lu SH.

BMC Cancer. 2011 Feb 3;11:52. doi: 10.1186/1471-2407-11-52.


[Expression and function of ECRG4 in hepatocellular carcinoma].

Chao C, Lai Q, Luo T, Tang G, Zhou R, Zhang W.

Zhonghua Bing Li Xue Za Zhi. 2015 Jul;44(7):486-9. Chinese.


Esophageal cancer-related gene-4 (ECRG4) interactions with the innate immunity receptor complex.

Podvin S, Dang X, Meads M, Kurabi A, Costantini T, Eliceiri BP, Baird A, Coimbra R.

Inflamm Res. 2015 Feb;64(2):107-18. doi: 10.1007/s00011-014-0789-2. Epub 2014 Dec 16.


Thrombin-processed Ecrg4 recruits myeloid cells and induces antitumorigenic inflammation.

Lee J, Dang X, Borboa A, Coimbra R, Baird A, Eliceiri BP.

Neuro Oncol. 2015 May;17(5):685-96. doi: 10.1093/neuonc/nou302. Epub 2014 Nov 5.


Down-regulation of ECRG4, a candidate tumor suppressor gene, in human breast cancer.

Sabatier R, Finetti P, Adelaide J, Guille A, Borg JP, Chaffanet M, Lane L, Birnbaum D, Bertucci F.

PLoS One. 2011;6(11):e27656. doi: 10.1371/journal.pone.0027656. Epub 2011 Nov 16.


[Mechanism of loss of human esophageal cancer-related gene 4 (ECRG4) gene expression in esophageal squamous cell carcinoma cell line EC9706].

Li LW, Yu XY, Li XY, Guo LP, Zhou Y, Lu SX.

Zhonghua Zhong Liu Za Zhi. 2011 Aug;33(8):570-3. Chinese.


Expression of ECRG4 is associated with lower proliferative potential of esophageal cancer cells.

Matsuzaki J, Torigoe T, Hirohashi Y, Tamura Y, Asanuma H, Nakazawa E, Saka E, Yasuda K, Takahashi S, Sato N.

Pathol Int. 2013 Aug;63(8):391-7. doi: 10.1111/pin.12079.


Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury.

Gonzalez AM, Podvin S, Lin SY, Miller MC, Botfield H, Leadbeater WE, Roberton A, Dang X, Knowling SE, Cardenas-Galindo E, Donahue JE, Stopa EG, Johanson CE, Coimbra R, Eliceiri BP, Baird A.

Fluids Barriers CNS. 2011 Jan 18;8(1):6. doi: 10.1186/2045-8118-8-6.


Neutrophils, not monocyte/macrophages, are the major splenic source of postburn IL-10.

Noel G, Wang Q, Schwemberger S, Hanson C, Giacalone N, Haar L, Ogle CK.

Shock. 2011 Aug;36(2):149-55. doi: 10.1097/SHK.0b013e3182205cbc.


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