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Targeted aerosolized delivery of ascorbate in the lungs of chlorine-exposed rats.

Bracher A, Doran SF, Squadrito GL, Postlethwait EM, Bowen L, Matalon S.

J Aerosol Med Pulm Drug Deliv. 2012 Dec;25(6):333-41. doi: 10.1089/jamp.2011.0963.


Post-exposure antioxidant treatment in rats decreases airway hyperplasia and hyperreactivity due to chlorine inhalation.

Fanucchi MV, Bracher A, Doran SF, Squadrito GL, Fernandez S, Postlethwait EM, Bowen L, Matalon S.

Am J Respir Cell Mol Biol. 2012 May;46(5):599-606. doi: 10.1165/rcmb.2011-0196OC.


Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite.

Yadav AK, Doran SF, Samal AA, Sharma R, Vedagiri K, Postlethwait EM, Squadrito GL, Fanucchi MV, Roberts LJ 2nd, Patel RP, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L362-9. doi: 10.1152/ajplung.00278.2010.


Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice.

Zarogiannis SG, Jurkuvenaite A, Fernandez S, Doran SF, Yadav AK, Squadrito GL, Postlethwait EM, Bowen L, Matalon S.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):386-92. doi: 10.1165/rcmb.2010-0432OC.


Mitigation of chlorine-induced lung injury by low-molecular-weight antioxidants.

Leustik M, Doran S, Bracher A, Williams S, Squadrito GL, Schoeb TR, Postlethwait E, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L733-43. doi: 10.1152/ajplung.90240.2008.


Mechanisms and modification of chlorine-induced lung injury in animals.

Yadav AK, Bracher A, Doran SF, Leustik M, Squadrito GL, Postlethwait EM, Matalon S.

Proc Am Thorac Soc. 2010 Jul;7(4):278-83. doi: 10.1513/pats.201001-009SM. Review.


Postexposure aerosolized heparin reduces lung injury in chlorine-exposed mice.

Zarogiannis SG, Wagener BM, Basappa S, Doran S, Rodriguez CA, Jurkuvenaite A, Pittet JF, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2014 Sep 1;307(5):L347-54. doi: 10.1152/ajplung.00152.2014.


Residual oil fly ash inhalation in guinea pigs: influence of absorbate and glutathione depletion.

Norwood J Jr, Ledbetter AD, Doerfler DL, Hatch GE.

Toxicol Sci. 2001 May;61(1):144-53.


Administration of nitrite after chlorine gas exposure prevents lung injury: effect of administration modality.

Samal AA, Honavar J, Brandon A, Bradley KM, Doran S, Liu Y, Dunaway C, Steele C, Postlethwait EM, Squadrito GL, Fanucchi MV, Matalon S, Patel RP.

Free Radic Biol Med. 2012 Oct 1;53(7):1431-9. doi: 10.1016/j.freeradbiomed.2012.08.007.


Phosgene- and chlorine-induced acute lung injury in rats: comparison of cardiopulmonary function and biomarkers in exhaled breath.

Luo S, TrĂ¼bel H, Wang C, Pauluhn J.

Toxicology. 2014 Dec 4;326:109-18. doi: 10.1016/j.tox.2014.10.010.


AEOL10150: a novel therapeutic for rescue treatment after toxic gas lung injury.

McGovern T, Day BJ, White CW, Powell WS, Martin JG.

Free Radic Biol Med. 2011 Mar 1;50(5):602-8. doi: 10.1016/j.freeradbiomed.2010.12.001.


Compromised concentrations of ascorbate in fluid lining the respiratory tract in human subjects after exposure to ozone.

Mudway IS, Krishna MT, Frew AJ, MacLeod D, Sandstrom T, Holgate ST, Kelly FJ.

Occup Environ Med. 1999 Jul;56(7):473-81.


Differential effects of ozone on lung epithelial lining fluid volume and protein content.

Cheng PW, Boat TF, Shaikh S, Wang OL, Hu PC, Costa DL.

Exp Lung Res. 1995 May-Jun;21(3):351-65.


In vivo lung deposition and sub-acute inhalation toxicity studies of nano-sized alendronate sodium as an antidote for inhaled toxic substances in Sprague Dawley rats.

Sultana S, Ali R, Talegaonkar S, Ahmad FJ, Mittal G, Bhatnagar A.

Environ Toxicol Pharmacol. 2013 Sep;36(2):636-47. doi: 10.1016/j.etap.2013.05.016.

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