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Items: 1 to 20 of 116


Obesity-insulin targeted genes in the 3p26-25 region in human studies and LG/J and SM/J mice.

Kraja AT, Lawson HA, Arnett DK, Borecki IB, Broeckel U, de las Fuentes L, Hunt SC, Province MA, Cheverud J, Rao DC.

Metabolism. 2012 Aug;61(8):1129-41. doi: 10.1016/j.metabol.2012.01.008. Epub 2012 Mar 3.


Quantitative trait loci for metabolic syndrome in the Hypertension Genetic Epidemiology Network study.

Kraja AT, Hunt SC, Pankow JS, Myers RH, Heiss G, Lewis CE, Rao DC, Province MA.

Obes Res. 2005 Nov;13(11):1885-90.


Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations.

Lawson HA, Cady JE, Partridge C, Wolf JB, Semenkovich CF, Cheverud JM.

PLoS Genet. 2011 Sep;7(9):e1002256. doi: 10.1371/journal.pgen.1002256. Epub 2011 Sep 8.


Two major QTLs and several others relate to factors of metabolic syndrome in the family blood pressure program.

Kraja AT, Rao DC, Weder AB, Cooper R, Curb JD, Hanis CL, Turner ST, de Andrade M, Hsiung CA, Quertermous T, Zhu X, Province MA.

Hypertension. 2005 Oct;46(4):751-7. Epub 2005 Sep 19.


Fine-mapping gene-by-diet interactions on chromosome 13 in a LG/J x SM/J murine model of obesity.

Ehrich TH, Hrbek T, Kenney-Hunt JP, Pletscher LS, Wang B, Semenkovich CF, Cheverud JM.

Diabetes. 2005 Jun;54(6):1863-72.


QTLs of factors of the metabolic syndrome and echocardiographic phenotypes: the hypertension genetic epidemiology network study.

Kraja AT, Huang P, Tang W, Hunt SC, North KE, Lewis CE, Devereux RB, de Simone G, Arnett DK, Rice T, Rao DC.

BMC Med Genet. 2008 Nov 27;9:103. doi: 10.1186/1471-2350-9-103.


Genome-wide linkage scan for the metabolic syndrome: the GENNID study.

Edwards KL, Hutter CM, Wan JY, Kim H, Monks SA.

Obesity (Silver Spring). 2008 Jul;16(7):1596-601. doi: 10.1038/oby.2008.236. Epub 2008 Apr 17.


Sex-specific findings from a genome-wide linkage analysis of human fatness in non-Hispanic whites and African Americans: the HyperGEN study.

Lewis CE, North KE, Arnett D, Borecki IB, Coon H, Ellison RC, Hunt SC, Oberman A, Rich SS, Province MA, Miller MB.

Int J Obes (Lond). 2005 Jun;29(6):639-49.


Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

Wing MR, Ziegler JM, Langefeld CD, Roh BH, Palmer ND, Mayer-Davis EJ, Rewers MJ, Haffner SM, Wagenknecht LE, Bowden DW.

Int J Obes (Lond). 2011 Sep;35(9):1173-82. doi: 10.1038/ijo.2010.244. Epub 2010 Nov 23.


Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome.

Kissebah AH, Sonnenberg GE, Myklebust J, Goldstein M, Broman K, James RG, Marks JA, Krakower GR, Jacob HJ, Weber J, Martin L, Blangero J, Comuzzie AG.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14478-83.


Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.

Lembertas AV, Pérusse L, Chagnon YC, Fisler JS, Warden CH, Purcell-Huynh DA, Dionne FT, Gagnon J, Nadeau A, Lusis AJ, Bouchard C.

J Clin Invest. 1997 Sep 1;100(5):1240-7.


Genome-wide scans for heritability of fasting serum insulin and glucose concentrations in hypertensive families.

Freedman BI, Rich SS, Sale MM, Heiss G, Djoussé L, Pankow JS, Province MA, Rao DC, Lewis CE, Chen YD, Beck SR; HyperGEN Investigators..

Diabetologia. 2005 Apr;48(4):661-8. Epub 2005 Mar 4. Erratum in: Diabetologia. 2005 Aug;48(8):1678.


The effect of dietary fat intake on hepatic gene expression in LG/J AND SM/J mice.

Partridge CG, Fawcett GL, Wang B, Semenkovich CF, Cheverud JM.

BMC Genomics. 2014 Feb 5;15:99. doi: 10.1186/1471-2164-15-99.


Major quantitative trait locus on chromosome 2 for glucose tolerance in diabetic SMXA-5 mouse established from non-diabetic SM/J and A/J strains.

Kobayashi M, Io F, Kawai T, Kumazawa M, Ikegami H, Nishimura M, Ohno T, Horio F.

Diabetologia. 2006 Mar;49(3):486-95. Epub 2006 Jan 31.


Analysis of metabolic syndrome components in >15 000 african americans identifies pleiotropic variants: results from the population architecture using genomics and epidemiology study.

Carty CL, Bhattacharjee S, Haessler J, Cheng I, Hindorff LA, Aroda V, Carlson CS, Hsu CN, Wilkens L, Liu S, Selvin E, Jackson R, North KE, Peters U, Pankow JS, Chatterjee N, Kooperberg C.

Circ Cardiovasc Genet. 2014 Aug;7(4):505-13. doi: 10.1161/CIRCGENETICS.113.000386. Epub 2014 Jul 14.


Genetic factors and diet affect long-bone length in the F34 LG,SM advanced intercross.

Norgard EA, Lawson HA, Pletscher LS, Wang B, Brooks VR, Wolf JB, Cheverud JM.

Mamm Genome. 2011 Apr;22(3-4):178-96. doi: 10.1007/s00335-010-9311-5. Epub 2010 Dec 19.


QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects.

Lin C, Theodorides ML, McDaniel AH, Tordoff MG, Zhang Q, Li X, Bosak N, Bachmanov AA, Reed DR.

PLoS One. 2013 Jul 29;8(7):e68776. doi: 10.1371/journal.pone.0068776. Print 2013.


Differential response to dietary fat in large (LG/J) and small (SM/J) inbred mouse strains.

Cheverud JM, Pletscher LS, Vaughn TT, Marshall B.

Physiol Genomics. 1999 Jul 15;1(1):33-9.


Bivariate genome-wide scan for metabolic phenotypes in non-diabetic Chinese individuals from the Stanford, Asia and Pacific Program of Hypertension and Insulin Resistance Family Study.

Chiu YF, Chuang LM, Kao HY, Ho LT, Ting CT, Hung YJ, Chen YD, Donlon T, Curb JD, Quertermous T, Hsiung CA.

Diabetologia. 2007 Aug;50(8):1631-40. Epub 2007 Jun 20.


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