Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 181

1.

High prevalence of polymorphism and low activity of thiopurine methyltransferase in patients with inflammatory bowel disease.

Larussa T, Suraci E, Lentini M, Nazionale I, Gallo L, Abenavoli L, Imeneo M, Costanzo FS, Cuda G, Luzza F.

Eur J Intern Med. 2012 Apr;23(3):273-7. doi: 10.1016/j.ejim.2011.12.002. Epub 2012 Jan 5.

PMID:
22385887
2.

Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease.

Coenen MJ, de Jong DJ, van Marrewijk CJ, Derijks LJ, Vermeulen SH, Wong DR, Klungel OH, Verbeek AL, Hooymans PM, Peters WH, te Morsche RH, Newman WG, Scheffer H, Guchelaar HJ, Franke B; TOPIC Recruitment Team.

Gastroenterology. 2015 Oct;149(4):907-17.e7. doi: 10.1053/j.gastro.2015.06.002. Epub 2015 Jun 11.

PMID:
26072396
3.

Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism.

Schwab M, Schäffeler E, Marx C, Fischer C, Lang T, Behrens C, Gregor M, Eichelbaum M, Zanger UM, Kaskas BA.

Pharmacogenetics. 2002 Aug;12(6):429-36.

PMID:
12172211
4.

Analysis of thiopurine S-methyltransferase genotypes in Japanese patients with inflammatory bowel disease.

Ban H, Andoh A, Tanaka A, Tsujikawa T, Sasaki M, Saito Y, Fujiyama Y.

Intern Med. 2008;47(19):1645-8. Epub 2008 Oct 1.

5.

Thiopurine methyltransferase gene polymorphisms in Chinese patients with inflammatory bowel disease.

Cao Q, Zhu Q, Shang Y, Gao M, Si J.

Digestion. 2009;79(1):58-63. doi: 10.1159/000205268. Epub 2009 Feb 28.

PMID:
19252404
6.

Limitations of extensive TPMT genotyping in the management of azathioprine-induced myelosuppression in IBD patients.

Dewit O, Moreels T, Baert F, Peeters H, Reenaers C, de Vos M, Van Hootegem P, Muls V, Veereman G, Mana F, Van Outryve M, Holvoet J, Naegels S, Piessevaux H, Horsmans Y, Gala JL; Belgian Inflammatory Bowel Disease Research Group (BIRD).

Clin Biochem. 2011 Sep;44(13):1062-6. doi: 10.1016/j.clinbiochem.2011.06.079. Epub 2011 Jun 24.

PMID:
21723857
7.

Thiopurine-methyltransferase variants in inflammatory bowel disease: prevalence and toxicity in Brazilian patients.

Carvalho AT, Esberard BC, Fróes RS, Rapozo DC, Grinman AB, Simão TA, Santos JC, Carneiro AJ, Ribeiro-Pinto LF, de Souza HS.

World J Gastroenterol. 2014 Mar 28;20(12):3327-34. doi: 10.3748/wjg.v20.i12.3327.

8.

Pharmacogenetics during standardised initiation of thiopurine treatment in inflammatory bowel disease.

Hindorf U, Lindqvist M, Peterson C, Söderkvist P, Ström M, Hjortswang H, Pousette A, Almer S.

Gut. 2006 Oct;55(10):1423-31. Epub 2006 Mar 16.

9.

Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease.

Gearry RB, Barclay ML, Burt MJ, Collett JA, Chapman BA, Roberts RL, Kennedy MA.

Aliment Pharmacol Ther. 2003 Aug 15;18(4):395-400.

10.

Thiopurine S-methyltransferase phenotype-genotype correlation in children with acute lymphoblastic leukemia.

Chrzanowska M, Kuehn M, Januszkiewicz-Lewandowska D, Kurzawski M, Droździk M.

Acta Pol Pharm. 2012 May-Jun;69(3):405-10.

11.

Impact of the heterozygous TPMT*1/*3C genotype on azathioprine-induced myelosuppression in kidney transplant recipients in Thailand.

Vannaprasaht S, Angsuthum S, Avihingsanon Y, Sirivongs D, Pongskul C, Makarawate P, Praditpornsilpa K, Tassaneeyakul W, Tassaneeyakul W.

Clin Ther. 2009 Jul;31(7):1524-33. doi: 10.1016/j.clinthera.2009.07.008.

PMID:
19695401
12.

Allelic variants of the thiopurine S-methyltransferase deficiency in patients with ulcerative colitis and in healthy controls.

Corominas H, Domènech M, González D, Diaz C, Roca M, García-González MA, Peña S, Baiget M.

Am J Gastroenterol. 2000 Sep;95(9):2313-7.

PMID:
11007234
13.

Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy.

Colombel JF, Ferrari N, Debuysere H, Marteau P, Gendre JP, Bonaz B, Soulé JC, Modigliani R, Touze Y, Catala P, Libersa C, Broly F.

Gastroenterology. 2000 Jun;118(6):1025-30.

PMID:
10833476
14.

Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

Marinaki AM, Ansari A, Duley JA, Arenas M, Sumi S, Lewis CM, Shobowale-Bakre el-M, Escuredo E, Fairbanks LD, Sanderson JD.

Pharmacogenetics. 2004 Mar;14(3):181-7.

PMID:
15167706
15.

Should thiopurine methyltransferase genotypes and phenotypes be measured before thiopurine therapy in patients with inflammatory bowel disease?

Fangbin Z, Xiang G, Minhu C, Liang D, Feng X, Min H, Pinjin H.

Ther Drug Monit. 2012 Dec;34(6):695-701. doi: 10.1097/FTD.0b013e3182731925.

PMID:
23149442
16.

Prevalence of mutations in thiopurine S-methyltransferase gene among Slovak IBD patients.

Desatova B, Hlavaty T, Balakova D, Pav I, Celec P, Gregus M, Zakuciova M, Hlista M, Horakova M, Kadasi L, Huorka M, Batovsky M.

Bratisl Lek Listy. 2013;114(6):330-2.

PMID:
23731044
17.

[Thiopurine S-methyltransferase gene polymorphism in Chilean blood donors].

Alvarez L L, Venegas S M, Larrondo L M, Becerra B N, Castro L A, Quera P R.

Rev Med Chil. 2009 Feb;137(2):185-92. doi: /S0034-98872009000200001. Epub 2009 Jun 10. Spanish.

18.

Thiopurine S-methyltransferase phenotype-genotype correlation in hemodialyzed patients.

Chrzanowska M, Kurzawski M, Droździk M, Mazik M, Oko A, Czekalski S.

Pharmacol Rep. 2006 Nov-Dec;58(6):973-8.

19.

Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment.

Uchiyama K, Nakamura M, Kubota T, Yamane T, Fujise K, Tajiri H.

J Gastroenterol. 2009;44(3):197-203. doi: 10.1007/s00535-008-2307-1. Epub 2009 Feb 13.

PMID:
19214663
20.

Thiopurine methyltransferase polymorphic tandem repeat: genotype-phenotype correlation analysis.

Yan L, Zhang S, Eiff B, Szumlanski CL, Powers M, O'Brien JF, Weinshilboum RM.

Clin Pharmacol Ther. 2000 Aug;68(2):210-9.

PMID:
10976552

Supplemental Content

Support Center