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Items: 1 to 20 of 84

1.

Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse.

Sun M, Mondal K, Patel V, Horner VL, Long AB, Cutler DJ, Caspary T, Zwick ME.

G3 (Bethesda). 2012 Jan;2(1):143-50. doi: 10.1534/g3.111.001669. Epub 2012 Jan 1.

2.

Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.

Andrews TD, Whittle B, Field MA, Balakishnan B, Zhang Y, Shao Y, Cho V, Kirk M, Singh M, Xia Y, Hager J, Winslade S, Sjollema G, Beutler B, Enders A, Goodnow CC.

Open Biol. 2012 May;2(5):120061. doi: 10.1098/rsob.120061.

3.

Phenotype-driven mouse ENU mutagenesis screens.

Caspary T.

Methods Enzymol. 2010;477:313-27. doi: 10.1016/S0076-6879(10)77016-6.

PMID:
20699148
4.

Mouse mutagenesis with the chemical supermutagen ENU.

Probst FJ, Justice MJ.

Methods Enzymol. 2010;477:297-312. doi: 10.1016/S0076-6879(10)77015-4.

PMID:
20699147
5.

Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice.

Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T.

Genes Environ. 2016 Apr 1;38:10. doi: 10.1186/s41021-016-0035-y. eCollection 2016.

6.

Characterization of ENU-induced Mutations in Red Blood Cell Structural Proteins.

Kildey K, Flower RL, Tran TV, Tunningley R, Harris J, Dean MM.

Comput Struct Biotechnol J. 2013 Sep 23;6:e201303012. doi: 10.5936/csbj.201303012. eCollection 2013.

7.

Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice.

Michaud EJ, Culiat CT, Klebig ML, Barker PE, Cain KT, Carpenter DJ, Easter LL, Foster CM, Gardner AW, Guo ZY, Houser KJ, Hughes LA, Kerley MK, Liu Z, Olszewski RE, Pinn I, Shaw GD, Shinpock SG, Wymore AM, Rinchik EM, Johnson DK.

BMC Genomics. 2005 Nov 21;6:164.

8.

ENU-induced mutant mice for a next-generation gene-targeting system.

Gondo Y, Fukumura R.

Prog Brain Res. 2009;179:29-34. doi: 10.1016/S0079-6123(09)17904-9. Epub 2009 Nov 20.

PMID:
20302815
9.

Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.

Bull KR, Rimmer AJ, Siggs OM, Miosge LA, Roots CM, Enders A, Bertram EM, Crockford TL, Whittle B, Potter PK, Simon MM, Mallon AM, Brown SD, Beutler B, Goodnow CC, Lunter G, Cornall RJ.

PLoS Genet. 2013;9(1):e1003219. doi: 10.1371/journal.pgen.1003219. Epub 2013 Jan 31.

10.

Genome-wide analysis of chemically induced mutations in mouse in phenotype-driven screens.

Bauer DC, McMorran BJ, Foote SJ, Burgio G.

BMC Genomics. 2015 Oct 26;16:866. doi: 10.1186/s12864-015-2073-4.

11.

Variant mapping and mutation discovery in inbred mice using next-generation sequencing.

Gallego-Llamas J, Timms AE, Geister KA, Lindsay A, Beier DR.

BMC Genomics. 2015 Nov 9;16:913. doi: 10.1186/s12864-015-2173-1.

12.

Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice.

Geister KA, Timms AE, Beier DR.

G3 (Bethesda). 2018 Feb 2;8(2):401-409. doi: 10.1534/g3.117.300292.

13.

Current strategies for mutation detection in phenotype-driven screens utilising next generation sequencing.

Simon MM, Moresco EM, Bull KR, Kumar S, Mallon AM, Beutler B, Potter PK.

Mamm Genome. 2015 Oct;26(9-10):486-500. doi: 10.1007/s00335-015-9603-x. Epub 2015 Oct 8. Review.

14.

Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells.

Chen Y, Yee D, Dains K, Chatterjee A, Cavalcoli J, Schneider E, Om J, Woychik RP, Magnuson T.

Nat Genet. 2000 Mar;24(3):314-7.

PMID:
10700191
15.

Creating a "hopeful monster": mouse forward genetic screens.

Horner VL, Caspary T.

Methods Mol Biol. 2011;770:313-36. doi: 10.1007/978-1-61779-210-6_12.

16.

Genome-wide ENU mutagenesis for the discovery of novel male fertility regulators.

Jamsai D, O'Bryan MK.

Syst Biol Reprod Med. 2010 Jun;56(3):246-59. doi: 10.3109/19396361003706424. Review.

PMID:
20536324
17.

N-ethyl-N-nitrosourea mutagenesis: boarding the mouse mutant express.

Cordes SP.

Microbiol Mol Biol Rev. 2005 Sep;69(3):426-39. Review.

18.

Improvement of ENU Mutagenesis Efficiency Using Serial Injection and Mismatch Repair Deficiency Mice.

Gallego-Llamas J, Timms AE, Pitstick R, Peters J, Carlson GA, Beier DR.

PLoS One. 2016 Jul 21;11(7):e0159377. doi: 10.1371/journal.pone.0159377. eCollection 2016.

20.

Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects.

Aigner B, Rathkolb B, Herbach N, Hrabé de Angelis M, Wanke R, Wolf E.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E232-40. Epub 2007 Dec 4. Review.

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