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Items: 1 to 20 of 166

1.

Silent information regulator 2 (Sir2) and Forkhead box O (FOXO) complement mitochondrial dysfunction and dopaminergic neuron loss in Drosophila PTEN-induced kinase 1 (PINK1) null mutant.

Koh H, Kim H, Kim MJ, Park J, Lee HJ, Chung J.

J Biol Chem. 2012 Apr 13;287(16):12750-8. doi: 10.1074/jbc.M111.337907. Epub 2012 Feb 29.

2.

PINK1 as a molecular checkpoint in the maintenance of mitochondrial function and integrity.

Koh H, Chung J.

Mol Cells. 2012 Jul;34(1):7-13. doi: 10.1007/s10059-012-0100-8. Epub 2012 May 18. Review.

3.

Tumor Necrosis Factor Receptor-associated Protein 1 (TRAP1) Mutation and TRAP1 Inhibitor Gamitrinib-triphenylphosphonium (G-TPP) Induce a Forkhead Box O (FOXO)-dependent Cell Protective Signal from Mitochondria.

Kim H, Yang J, Kim MJ, Choi S, Chung JR, Kim JM, Yoo YH, Chung J, Koh H.

J Biol Chem. 2016 Jan 22;291(4):1841-53. doi: 10.1074/jbc.M115.656934. Epub 2015 Dec 2.

4.

Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.

Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, Millan I, Shen A, Saxton W, Kanao T, Takahashi R, Hattori N, Imai Y, Lu B.

PLoS Genet. 2012;8(3):e1002537. doi: 10.1371/journal.pgen.1002537. Epub 2012 Mar 1.

5.

Drosophila CHIP protects against mitochondrial dysfunction by acting downstream of Pink1 in parallel with Parkin.

Chen J, Xue J, Ruan J, Zhao J, Tang B, Duan R.

FASEB J. 2017 Dec;31(12):5234-5245. doi: 10.1096/fj.201700011R. Epub 2017 Aug 4.

PMID:
28778978
6.

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.

Imai Y, Kanao T, Sawada T, Kobayashi Y, Moriwaki Y, Ishida Y, Takeda K, Ichijo H, Lu B, Takahashi R.

PLoS Genet. 2010 Dec 2;6(12):e1001229. doi: 10.1371/journal.pgen.1001229.

7.

Glutathione S-transferase omega suppresses the defective phenotypes caused by PINK1 loss-of-function in Drosophila.

Kim K, Yim J.

Biochem Biophys Res Commun. 2013 Aug 9;437(4):615-9. doi: 10.1016/j.bbrc.2013.07.011. Epub 2013 Jul 15.

PMID:
23867819
8.

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.

Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M.

Nature. 2006 Jun 29;441(7097):1162-6. Epub 2006 May 3.

PMID:
16672981
9.

PINK1-mediated phosphorylation of Miro inhibits synaptic growth and protects dopaminergic neurons in Drosophila.

Tsai PI, Course MM, Lovas JR, Hsieh CH, Babic M, Zinsmaier KE, Wang X.

Sci Rep. 2014 Nov 7;4:6962. doi: 10.1038/srep06962.

10.
11.

Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.

Costa AC, Loh SH, Martins LM.

Cell Death Dis. 2013 Jan 17;4:e467. doi: 10.1038/cddis.2012.205.

12.

The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants.

Vilain S, Esposito G, Haddad D, Schaap O, Dobreva MP, Vos M, Van Meensel S, Morais VA, De Strooper B, Verstreken P.

PLoS Genet. 2012 Jan;8(1):e1002456. doi: 10.1371/journal.pgen.1002456. Epub 2012 Jan 5.

13.

PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila.

Shiba-Fukushima K, Inoshita T, Hattori N, Imai Y.

PLoS Genet. 2014 Jun 5;10(6):e1004391. doi: 10.1371/journal.pgen.1004391. eCollection 2014 Jun.

14.

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin.

Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, Bae E, Kim J, Shong M, Kim JM, Chung J.

Nature. 2006 Jun 29;441(7097):1157-61. Epub 2006 May 3.

PMID:
16672980
15.

TRAP1 rescues PINK1 loss-of-function phenotypes.

Zhang L, Karsten P, Hamm S, Pogson JH, Müller-Rischart AK, Exner N, Haass C, Whitworth AJ, Winklhofer KF, Schulz JB, Voigt A.

Hum Mol Genet. 2013 Jul 15;22(14):2829-41. doi: 10.1093/hmg/ddt132. Epub 2013 Mar 21.

16.

UCP4A protects against mitochondrial dysfunction and degeneration in pink1/parkin models of Parkinson's disease.

Wu K, Liu J, Zhuang N, Wang T.

FASEB J. 2014 Dec;28(12):5111-21. doi: 10.1096/fj.14-255802. Epub 2014 Aug 21.

17.

PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control.

Zhuang N, Li L, Chen S, Wang T.

Cell Death Dis. 2016 Dec 1;7(12):e2501. doi: 10.1038/cddis.2016.396.

18.

The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

Park J, Lee G, Chung J.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):518-23. doi: 10.1016/j.bbrc.2008.11.086. Epub 2008 Dec 3.

PMID:
19056353
19.

The PINK1/Parkin pathway regulates mitochondrial morphology.

Poole AC, Thomas RE, Andrews LA, McBride HM, Whitworth AJ, Pallanck LJ.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1638-43. doi: 10.1073/pnas.0709336105. Epub 2008 Jan 29.

20.

Mask loss-of-function rescues mitochondrial impairment and muscle degeneration of Drosophila pink1 and parkin mutants.

Zhu M, Li X, Tian X, Wu C.

Hum Mol Genet. 2015 Jun 1;24(11):3272-85. doi: 10.1093/hmg/ddv081. Epub 2015 Mar 5.

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