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Items: 1 to 20 of 101

1.

Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice.

Carr RM, Patel RT, Rao V, Dhir R, Graham MJ, Crooke RM, Ahima RS.

Am J Physiol Regul Integr Comp Physiol. 2012 Apr 15;302(8):R996-1003. doi: 10.1152/ajpregu.00177.2011. Epub 2012 Feb 29.

2.

Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide.

Imai Y, Varela GM, Jackson MB, Graham MJ, Crooke RM, Ahima RS.

Gastroenterology. 2007 May;132(5):1947-54. Epub 2007 Feb 23.

PMID:
17484887
3.

Inhibition of ADRP prevents diet-induced insulin resistance.

Varela GM, Antwi DA, Dhir R, Yin X, Singhal NS, Graham MJ, Crooke RM, Ahima RS.

Am J Physiol Gastrointest Liver Physiol. 2008 Sep;295(3):G621-8. doi: 10.1152/ajpgi.90204.2008. Epub 2008 Jul 31.

4.

Inhibiting monoacylglycerol acyltransferase 1 ameliorates hepatic metabolic abnormalities but not inflammation and injury in mice.

Soufi N, Hall AM, Chen Z, Yoshino J, Collier SL, Mathews JC, Brunt EM, Albert CJ, Graham MJ, Ford DA, Finck BN.

J Biol Chem. 2014 Oct 24;289(43):30177-88. doi: 10.1074/jbc.M114.595850. Epub 2014 Sep 11.

5.

Second-generation antisense oligonucleotides against Ī²-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance.

Popov VB, Jornayvaz FR, Akgul EO, Kanda S, Jurczak MJ, Zhang D, Abudukadier A, Majumdar SK, Guigni B, Petersen KF, Manchem VP, Bhanot S, Shulman GI, Samuel VT.

FASEB J. 2016 Mar;30(3):1207-17. doi: 10.1096/fj.15-271999. Epub 2015 Dec 7.

6.

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice.

Yu XX, Murray SF, Pandey SK, Booten SL, Bao D, Song XZ, Kelly S, Chen S, McKay R, Monia BP, Bhanot S.

Hepatology. 2005 Aug;42(2):362-71.

PMID:
16001399
7.

Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression.

Imai Y, Boyle S, Varela GM, Caron E, Yin X, Dhir R, Dhir R, Graham MJ, Ahima RS.

Physiol Genomics. 2012 Nov 15;44(22):1125-31. doi: 10.1152/physiolgenomics.00045.2012. Epub 2012 Sep 25.

8.

Perilipin discerns chronic from acute hepatocellular steatosis.

Pawella LM, Hashani M, Eiteneuer E, Renner M, Bartenschlager R, Schirmacher P, Straub BK.

J Hepatol. 2014 Mar;60(3):633-42. doi: 10.1016/j.jhep.2013.11.007. Epub 2013 Nov 19.

PMID:
24269473
9.

Reduced adiposity and improved insulin sensitivity in obese mice with antisense suppression of 4E-BP2 expression.

Yu XX, Pandey SK, Booten SL, Murray SF, Monia BP, Bhanot S.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E530-9. doi: 10.1152/ajpendo.00350.2007. Epub 2008 Jan 15.

10.

Reversion of steatosis by SREBP-1c antisense oligonucleotide did not improve hepatic insulin action in diet-induced obesity mice.

Vitto MF, Luz G, Luciano TF, Marques SO, Souza DR, Pinho RA, Lira FS, Cintra DE, De Souza CT.

Horm Metab Res. 2012 Nov;44(12):885-90. doi: 10.1055/s-0032-1321819. Epub 2012 Aug 29.

PMID:
22932913
11.

Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance.

Choi CS, Savage DB, Kulkarni A, Yu XX, Liu ZX, Morino K, Kim S, Distefano A, Samuel VT, Neschen S, Zhang D, Wang A, Zhang XM, Kahn M, Cline GW, Pandey SK, Geisler JG, Bhanot S, Monia BP, Shulman GI.

J Biol Chem. 2007 Aug 3;282(31):22678-88. Epub 2007 May 27.

12.

Fructus Xanthii attenuates hepatic steatosis in rats fed on high-fat diet.

Li X, Li Z, Xue M, Ou Z, Liu M, Yang M, Liu S, Yang S, Li X.

PLoS One. 2013 Apr 9;8(4):e61499. doi: 10.1371/journal.pone.0061499. Print 2013.

13.

CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance.

Brown JM, Betters JL, Lord C, Ma Y, Han X, Yang K, Alger HM, Melchior J, Sawyer J, Shah R, Wilson MD, Liu X, Graham MJ, Lee R, Crooke R, Shulman GI, Xue B, Shi H, Yu L.

J Lipid Res. 2010 Nov;51(11):3306-15. doi: 10.1194/jlr.M010256. Epub 2010 Aug 27.

14.

Angiopoietin-like proteinĀ 4 improves glucose tolerance and insulin resistance but induces liver steatosis in high-fat-diet mice.

Wang Y, Liu LM, Wei L, Ye WW, Meng XY, Chen F, Xiao Q, Chen JY, Zhou Y.

Mol Med Rep. 2016 Oct;14(4):3293-300. doi: 10.3892/mmr.2016.5637. Epub 2016 Aug 18.

PMID:
27573470
15.

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, Pandey SK, Bhanot S, Monia BP, Li YX, Diehl AM.

Hepatology. 2007 Jun;45(6):1366-74.

PMID:
17476695
16.
17.

Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance.

Wiedemann MS, Wueest S, Item F, Schoenle EJ, Konrad D.

Am J Physiol Endocrinol Metab. 2013 Aug 1;305(3):E388-95. doi: 10.1152/ajpendo.00179.2013. Epub 2013 Jun 4.

18.

Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.

Liu LF, Purushotham A, Wendel AA, Belury MA.

Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1671-82. Epub 2007 Feb 22.

19.

Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.

20.

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.

PMID:
23928105

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