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Items: 1 to 20 of 125

1.

Human O-sulfated metabolites of (-)-epicatechin and methyl-(-)-epicatechin are poor substrates for commercial aryl-sulfatases: implications for studies concerned with quantifying epicatechin bioavailability.

Saha S, Hollands W, Needs PW, Ostertag LM, de Roos B, Duthie GG, Kroon PA.

Pharmacol Res. 2012 Jun;65(6):592-602. doi: 10.1016/j.phrs.2012.02.005. Epub 2012 Feb 25.

PMID:
22373658
2.

Identification of O-methyl-(-)-epicatechin-O-sulphate metabolites by mass-spectrometry after O-methylation with trimethylsilyldiazomethane.

Actis-Goretta L, Lévèques A, Giuffrida F, Destaillats F, Nagy K.

J Chromatogr A. 2012 Jul 6;1245:150-7. doi: 10.1016/j.chroma.2012.05.042. Epub 2012 May 17.

PMID:
22663977
3.

Elucidation of (-)-epicatechin metabolites after ingestion of chocolate by healthy humans.

Actis-Goretta L, Lévèques A, Giuffrida F, Romanov-Michailidis F, Viton F, Barron D, Duenas-Paton M, Gonzalez-Manzano S, Santos-Buelga C, Williamson G, Dionisi F.

Free Radic Biol Med. 2012 Aug 15;53(4):787-95. doi: 10.1016/j.freeradbiomed.2012.05.023. Epub 2012 Jun 1.

PMID:
22664313
4.

Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: differences between human and rat.

Natsume M, Osakabe N, Oyama M, Sasaki M, Baba S, Nakamura Y, Osawa T, Terao J.

Free Radic Biol Med. 2003 Apr 1;34(7):840-9.

PMID:
12654472
5.

Bioavailability of (-)-epicatechin upon intake of chocolate and cocoa in human volunteers.

Baba S, Osakabe N, Yasuda A, Natsume M, Takizawa T, Nakamura T, Terao J.

Free Radic Res. 2000 Nov;33(5):635-41.

PMID:
11200094
6.

In vivo comparison of the bioavailability of (+)-catechin, (-)-epicatechin and their mixture in orally administered rats.

Baba S, Osakabe N, Natsume M, Muto Y, Takizawa T, Terao J.

J Nutr. 2001 Nov;131(11):2885-91.

PMID:
11694613
7.

Uptake and metabolism of epicatechin and its access to the brain after oral ingestion.

Abd El Mohsen MM, Kuhnle G, Rechner AR, Schroeter H, Rose S, Jenner P, Rice-Evans CA.

Free Radic Biol Med. 2002 Dec 15;33(12):1693-702.

PMID:
12488137
8.

The effects of milk as a food matrix for polyphenols on the excretion profile of cocoa (-)-epicatechin metabolites in healthy human subjects.

Roura E, Andrés-Lacueva C, Estruch R, Lourdes Mata Bilbao M, Izquierdo-Pulido M, Lamuela-Raventós RM.

Br J Nutr. 2008 Oct;100(4):846-51. doi: 10.1017/S0007114508922534. Epub 2008 Feb 7.

PMID:
18257943
9.

Chemical synthesis and characterization of epicatechin glucuronides and sulfates: bioanalytical standards for epicatechin metabolite identification.

Zhang M, Jagdmann GE Jr, Van Zandt M, Sheeler R, Beckett P, Schroeter H.

J Nat Prod. 2013 Feb 22;76(2):157-69. doi: 10.1021/np300568m. Epub 2013 Jan 28.

10.

Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat.

Kohri T, Suzuki M, Nanjo F.

J Agric Food Chem. 2003 Aug 27;51(18):5561-6.

PMID:
12926915
11.

Human urine: epicatechin metabolites and antioxidant activity after cocoa beverage intake.

Roura E, Almajano MP, Bilbao ML, Andrés-Lacueva C, Estruch R, Lamuela-Raventós RM.

Free Radic Res. 2007 Aug;41(8):943-9.

PMID:
17654051
12.

Analysis of urinary metabolites of tea catechins by liquid chromatography/electrospray ionization mass spectrometry.

Li C, Meng X, Winnik B, Lee MJ, Lu H, Sheng S, Buckley B, Yang CS.

Chem Res Toxicol. 2001 Jun;14(6):702-7.

PMID:
11409941
13.

Milk decreases urinary excretion but not plasma pharmacokinetics of cocoa flavan-3-ol metabolites in humans.

Mullen W, Borges G, Donovan JL, Edwards CA, Serafini M, Lean ME, Crozier A.

Am J Clin Nutr. 2009 Jun;89(6):1784-91. doi: 10.3945/ajcn.2008.27339. Epub 2009 Apr 29.

PMID:
19403635
14.

Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.

Chow HH, Hakim IA, Vining DR, Crowell JA, Ranger-Moore J, Chew WM, Celaya CA, Rodney SR, Hara Y, Alberts DS.

Clin Cancer Res. 2005 Jun 15;11(12):4627-33.

15.

Identification of (-)-epicatechin metabolites and their metabolic fate in the rat.

Okushio K, Suzuki M, Matsumoto N, Nanjo F, Hara Y.

Drug Metab Dispos. 1999 Feb;27(2):309-16.

16.

Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects.

Rodriguez-Mateos A, Cifuentes-Gomez T, Gonzalez-Salvador I, Ottaviani JI, Schroeter H, Kelm M, Heiss C, Spencer JP.

Mol Nutr Food Res. 2015 Aug;59(8):1504-12. doi: 10.1002/mnfr.201500091. Epub 2015 Jun 12.

PMID:
25981347
17.

Glucuronidation and methylation of procyanidin dimers b2 and 3,3″-di-o-galloyl-b2 and corresponding monomers epicatechin and 3-o-galloyl-epicatechin in mouse liver.

Shrestha SP, Thompson JA, Wempe MF, Gu M, Agarwal R, Agarwal C.

Pharm Res. 2012 Mar;29(3):856-65. doi: 10.1007/s11095-011-0614-3. Epub 2011 Nov 9.

18.

Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy.

Stalmach A, Mullen W, Steiling H, Williamson G, Lean ME, Crozier A.

Mol Nutr Food Res. 2010 Mar;54(3):323-34. doi: 10.1002/mnfr.200900194.

PMID:
19937856
19.

A comprehensive evaluation of the [2-14C](-)-epicatechin metabolome in rats.

Borges G, van der Hooft JJJ, Crozier A.

Free Radic Biol Med. 2016 Oct;99:128-138. doi: 10.1016/j.freeradbiomed.2016.08.001. Epub 2016 Aug 3.

PMID:
27495388
20.

Simultaneous determination of catechin, epicatechin and epicatechin gallate in rat plasma by LC-ESI-MS/MS for pharmacokinetic studies after oral administration of Cynomorium songaricum extract.

Zhang QH, Wang WB, Li J, Chang YX, Wang YF, Zhang J, Zhang BL, Gao XM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jan 1;880(1):168-71. doi: 10.1016/j.jchromb.2011.11.021. Epub 2011 Nov 20.

PMID:
22153330

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