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Items: 1 to 20 of 125

1.

Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks.

Newman AM, Gallo NB, Hancox LS, Miller NJ, Radeke CM, Maloney MA, Cooper JB, Hageman GS, Anderson DH, Johnson LV, Radeke MJ.

Genome Med. 2012 Feb 24;4(2):16. doi: 10.1186/gm315.

2.

Pathway activation profiling reveals new insights into age-related macular degeneration and provides avenues for therapeutic interventions.

Makarev E, Cantor C, Zhavoronkov A, Buzdin A, Aliper A, Csoka AB.

Aging (Albany NY). 2014 Dec;6(12):1064-75.

3.

Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration.

Bennis A, Gorgels TG, Ten Brink JB, van der Spek PJ, Bossers K, Heine VM, Bergen AA.

PLoS One. 2015 Oct 30;10(10):e0141597. doi: 10.1371/journal.pone.0141597. eCollection 2015.

4.

Altered gene expression in dry age-related macular degeneration suggests early loss of choroidal endothelial cells.

Whitmore SS, Braun TA, Skeie JM, Haas CM, Sohn EH, Stone EM, Scheetz TE, Mullins RF.

Mol Vis. 2013 Nov 16;19:2274-97. eCollection 2013.

5.

Transcriptomic analysis across nasal, temporal, and macular regions of human neural retina and RPE/choroid by RNA-Seq.

Whitmore SS, Wagner AH, DeLuca AP, Drack AV, Stone EM, Tucker BA, Zeng S, Braun TA, Mullins RF, Scheetz TE.

Exp Eye Res. 2014 Dec;129:93-106. doi: 10.1016/j.exer.2014.11.001. Epub 2014 Nov 5.

6.

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration.

Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF.

Prog Retin Eye Res. 2001 Nov;20(6):705-32. Review.

PMID:
11587915
7.

Restoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degeneration.

Radeke MJ, Radeke CM, Shih YH, Hu J, Bok D, Johnson LV, Coffey PJ.

Genome Med. 2015 Jun 19;7(1):58. doi: 10.1186/s13073-015-0183-x. eCollection 2015.

8.

Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD.

Ma W, Zhao L, Fontainhas AM, Fariss RN, Wong WT.

PLoS One. 2009 Nov 20;4(11):e7945. doi: 10.1371/journal.pone.0007945.

10.

Stem cell based therapies for age-related macular degeneration: The promises and the challenges.

Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rowland T, Clegg DO, Kashani AH, Hinton DR, Humayun MS.

Prog Retin Eye Res. 2015 Sep;48:1-39. doi: 10.1016/j.preteyeres.2015.06.004. Epub 2015 Jun 23. Review.

PMID:
26113213
11.

Systems Biology Profiling of AMD on the Basis of Gene Expression.

Abu-Asab MS, Salazar J, Tuo J, Chan CC.

J Ophthalmol. 2013;2013:453934. doi: 10.1155/2013/453934. Epub 2013 Nov 14.

12.

Optical coherence tomography for age-related macular degeneration and diabetic macular edema: an evidence-based analysis.

Health Quality Ontario.

Ont Health Technol Assess Ser. 2009;9(13):1-22. Epub 2009 Sep 1.

13.

Extreme retinal remodeling triggered by light damage: implications for age related macular degeneration.

Marc RE, Jones BW, Watt CB, Vazquez-Chona F, Vaughan DK, Organisciak DT.

Mol Vis. 2008 Apr 25;14:782-806.

14.

Reduced zinc and copper in the retinal pigment epithelium and choroid in age-related macular degeneration.

Erie JC, Good JA, Butz JA, Pulido JS.

Am J Ophthalmol. 2009 Feb;147(2):276-282.e1. doi: 10.1016/j.ajo.2008.08.014. Epub 2008 Oct 9.

PMID:
18848316
15.

Immunological factors in the pathogenesis and treatment of age-related macular degeneration.

Kijlstra A, La Heij E, Hendrikse F.

Ocul Immunol Inflamm. 2005 Feb;13(1):3-11. Review.

PMID:
15804763
17.

Excess lead in the neural retina in age-related macular degeneration.

Erie JC, Good JA, Butz JA.

Am J Ophthalmol. 2009 Dec;148(6):890-4. doi: 10.1016/j.ajo.2009.07.001. Epub 2009 Sep 5.

PMID:
19733830
18.

Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degeneration.

Mullins RF, Johnson MN, Faidley EA, Skeie JM, Huang J.

Invest Ophthalmol Vis Sci. 2011 Mar 1;52(3):1606-12. doi: 10.1167/iovs.10-6476.

19.

Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration.

Saini JS, Corneo B, Miller JD, Kiehl TR, Wang Q, Boles NC, Blenkinsop TA, Stern JH, Temple S.

Cell Stem Cell. 2017 May 4;20(5):635-647.e7. doi: 10.1016/j.stem.2016.12.015. Epub 2017 Jan 26.

PMID:
28132833
20.

Outer retinal corrugations in age-related macular degeneration.

Ooto S, Vongkulsiri S, Sato T, Suzuki M, Curcio CA, Spaide RF.

JAMA Ophthalmol. 2014 Jul;132(7):806-13. doi: 10.1001/jamaophthalmol.2014.1871.

PMID:
24801396

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