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Items: 1 to 20 of 243

1.

A switch in hepatic cortisol metabolism across the spectrum of non alcoholic fatty liver disease.

Ahmed A, Rabbitt E, Brady T, Brown C, Guest P, Bujalska IJ, Doig C, Newsome PN, Hubscher S, Elias E, Adams DH, Tomlinson JW, Stewart PM.

PLoS One. 2012;7(2):e29531. doi: 10.1371/journal.pone.0029531. Epub 2012 Feb 20.

2.

Hepatic 11beta-HSD1 mRNA expression in fatty liver and nonalcoholic steatohepatitis.

Konopelska S, Kienitz T, Hughes B, Pirlich M, Bauditz J, Lochs H, Strasburger CJ, Stewart PM, Quinkler M.

Clin Endocrinol (Oxf). 2009 Apr;70(4):554-60. doi: 10.1111/j.1365-2265.2008.03358.x.

PMID:
18665910
3.

Overexpression of hepatic 5α-reductase and 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue is associated with hyperinsulinemia in morbidly obese patients.

Baudrand R, Domínguez JM, Carvajal CA, Riquelme A, Campino C, Macchiavello S, Bozinovic M, Morales M, Pizarro M, Solis N, Escalona A, Boza C, Arrese M, Fardella CE.

Metabolism. 2011 Dec;60(12):1775-80. doi: 10.1016/j.metabol.2011.05.001. Epub 2011 Jun 24.

PMID:
21704348
4.

Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.

Lavery GG, Zielinska AE, Gathercole LL, Hughes B, Semjonous N, Guest P, Saqib K, Sherlock M, Reynolds G, Morgan SA, Tomlinson JW, Walker EA, Rabbitt EH, Stewart PM.

Endocrinology. 2012 Jul;153(7):3236-48. doi: 10.1210/en.2012-1019. Epub 2012 May 3.

5.

Overexpression of 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue and portal hypercortisolism in non-alcoholic fatty liver disease.

Candia R, Riquelme A, Baudrand R, Carvajal CA, Morales M, Solís N, Pizarro M, Escalona A, Carrasco G, Boza C, Pérez G, Padilla O, Cerda J, Fardella CE, Arrese M.

Liver Int. 2012 Mar;32(3):392-9. doi: 10.1111/j.1478-3231.2011.02685.x. Epub 2011 Dec 4.

PMID:
22136330
6.

Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver.

Westerbacka J, Yki-Järvinen H, Vehkavaara S, Häkkinen AM, Andrew R, Wake DJ, Seckl JR, Walker BR.

J Clin Endocrinol Metab. 2003 Oct;88(10):4924-31.

PMID:
14557475
7.

Growth hormone, insulin-like growth factor-I and the cortisol-cortisone shuttle.

Stewart PM, Toogood AA, Tomlinson JW.

Horm Res. 2001;56 Suppl 1:1-6. Review.

PMID:
11786677
8.

Increased whole-body and sustained liver cortisol regeneration by 11beta-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target for enzyme inhibition.

Stimson RH, Andrew R, McAvoy NC, Tripathi D, Hayes PC, Walker BR.

Diabetes. 2011 Mar;60(3):720-5. doi: 10.2337/db10-0726. Epub 2011 Jan 24.

9.

In vivo activity of 11beta-hydroxysteroid dehydrogenase type 1 and free fatty acid-induced insulin resistance.

Mai K, Kullmann V, Bobbert T, Maser-Gluth C, Möhlig M, Bähr V, Pfeiffer AF, Spranger J, Diederich S.

Clin Endocrinol (Oxf). 2005 Oct;63(4):442-9.

PMID:
16181237
11.

Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism.

Sigurjonsdottir HA, Andrew R, Stimson RH, Johannsson G, Walker BR.

Eur J Endocrinol. 2009 Sep;161(3):375-80. doi: 10.1530/EJE-09-0315. Epub 2009 Jun 23.

12.
13.

In vivo activity of 11β-hydroxysteroid dehydrogenase type 1 in man: effects of prednisolone and chenodesoxycholic acid.

Diederich S, Quinkler M, Mai K, Schöneshöfer M, Baehr V, Pfeiffer A, Oelkers W, Eigendorff E.

Horm Metab Res. 2011 Jan;43(1):66-71. doi: 10.1055/s-0030-1267170. Epub 2010 Oct 5.

PMID:
20925019
14.

Liver upregulation of genes involved in cortisol production and action is associated with metabolic syndrome in morbidly obese patients.

Torrecilla E, Fernández-Vázquez G, Vicent D, Sánchez-Franco F, Barabash A, Cabrerizo L, Sánchez-Pernaute A, Torres AJ, Rubio MA.

Obes Surg. 2012 Mar;22(3):478-86. doi: 10.1007/s11695-011-0524-9.

PMID:
21964795
15.

Tissue-specific dysregulation of cortisol metabolism in human obesity.

Rask E, Olsson T, Söderberg S, Andrew R, Livingstone DE, Johnson O, Walker BR.

J Clin Endocrinol Metab. 2001 Mar;86(3):1418-21.

PMID:
11238541
16.

Induction of hepatic 11beta-hydroxysteroid dehydrogenase type 1 in patients with alcoholic liver disease.

Ahmed A, Saksena S, Sherlock M, Olliff SP, Elias E, Stewart PM.

Clin Endocrinol (Oxf). 2008 Jun;68(6):898-903. Epub 2007 Nov 19.

PMID:
18031327
17.

11beta-hydroxysteroid dehydrogenase type 1 and obesity.

Morton NM, Seckl JR.

Front Horm Res. 2008;36:146-64. doi: 10.1159/0000115363. Review.

PMID:
18230901
18.

Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.

Wake DJ, Stimson RH, Tan GD, Homer NZ, Andrew R, Karpe F, Walker BR.

J Clin Endocrinol Metab. 2007 May;92(5):1848-56. Epub 2007 Feb 27.

PMID:
17327378
19.

Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11beta-hydroxysteroid dehydrogenase type 1) gene.

Iwasaki Y, Takayasu S, Nishiyama M, Tsugita M, Taguchi T, Asai M, Yoshida M, Kambayashi M, Hashimoto K.

Mol Cell Endocrinol. 2008 Mar 26;285(1-2):10-8. doi: 10.1016/j.mce.2008.01.012. Epub 2008 Feb 2.

PMID:
18313835
20.

Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in patients with chronic rhinosinusitis and their possible contribution to local glucocorticoid activation in sinus mucosa.

Jun YJ, Park SJ, Kim TH, Lee SH, Lee KJ, Hwang SM, Lee SH.

J Allergy Clin Immunol. 2014 Oct;134(4):926-934.e6. doi: 10.1016/j.jaci.2014.03.033. Epub 2014 May 5.

PMID:
24810847

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